STRINGSTRING
CSF1R CSF1R MITF MITF JUN JUN LOC114049642 LOC114049642 ENSVURP00010009787 ENSVURP00010009787 ENSVURP00010009777 ENSVURP00010009777 SYK SYK MAP3K7 MAP3K7 CAMK4 CAMK4 ENSVURP00010008190 ENSVURP00010008190 TRAF2 TRAF2 ENSVURP00010007417 ENSVURP00010007417 LOC114034206 LOC114034206 AKT1 AKT1 CREB1 CREB1 NCF1 NCF1 NCF4 NCF4 SPIB SPIB ENSVURP00010005272 ENSVURP00010005272 ENSVURP00010004801 ENSVURP00010004801 IFNGR2 IFNGR2 IFNAR1 IFNAR1 IFNAR2 IFNAR2 ENSVURP00010004532 ENSVURP00010004532 ENSVURP00010004522 ENSVURP00010004522 IFNGR1 IFNGR1 TGFB1 TGFB1 LOC114047099 LOC114047099 TAB1 TAB1 BTK BTK TAB2 TAB2 LOC114047681 LOC114047681 TNF TNF LOC114047683 LOC114047683 LCP2 LCP2 MAPK11 MAPK11 MAPK12 MAPK12 ENSVURP00010002081 ENSVURP00010002081 NFKB2 NFKB2 RELA RELA FOSL1 FOSL1 LOC114042161 LOC114042161 BLNK BLNK RELB RELB MAP2K7 MAP2K7 IFNG IFNG PIK3CD PIK3CD STAT2 STAT2 TYROBP TYROBP FYN FYN IRF9 IRF9 TGFBR2 TGFBR2 ENSVURP00010029447 ENSVURP00010029447 ENSVURP00010029419 ENSVURP00010029419 MAPK10 MAPK10 MAPK1 MAPK1 ENSVURP00010028243 ENSVURP00010028243 ENSVURP00010027685 ENSVURP00010027685 IL1R1 IL1R1 NFKB1 NFKB1 PPP3CA PPP3CA CYBA CYBA NFKBIA NFKBIA FOSL2 FOSL2 NFATC1 NFATC1 RELCH RELCH AKT2 AKT2 LOC114053487 LOC114053487 CYLD CYLD MAPK9 MAPK9 SQSTM1 SQSTM1 PIK3R1 PIK3R1 MAPK13 MAPK13 CALCR CALCR MAPK14 MAPK14 IKBKG IKBKG NFATC2 NFATC2 TNFRSF1A TNFRSF1A ENSVURP00010023958 ENSVURP00010023958 FOS FOS STAT1 STAT1 MAP2K1 MAP2K1 LOC114024909 LOC114024909 ENSVURP00010022479 ENSVURP00010022479 ENSVURP00010022363 ENSVURP00010022363 TNFRSF11B TNFRSF11B ENSVURP00010021762 ENSVURP00010021762 LOC114048474 LOC114048474 GAB2 GAB2 PLCG2 PLCG2 MAPK8 MAPK8 LOC114049642-2 LOC114049642-2 CHUK CHUK TNFRSF11A TNFRSF11A ENSVURP00010019693 ENSVURP00010019693 JUND JUND PIK3R2 PIK3R2 PTK6 PTK6 SRMS SRMS PPP3CC PPP3CC ENSVURP00010019380 ENSVURP00010019380 ENSVURP00010018742 ENSVURP00010018742 PPP3CB PPP3CB CSF1 CSF1 PPARG PPARG PPP3R1 PPP3R1 PIK3CA PIK3CA JUNB JUNB IFNB1 IFNB1 MAP2K6 MAP2K6 ACP5 ACP5 ENSVURP00010015483 ENSVURP00010015483 GRB2 GRB2 ENSVURP00010015465 ENSVURP00010015465 ENSVURP00010015457 ENSVURP00010015457 TRAF6 TRAF6 NOX1 NOX1 LOC114051561 LOC114051561 SOCS3 SOCS3 TGFB2 TGFB2 NCF2 NCF2 SPI1 SPI1 TEC TEC TNFSF11 TNFSF11 ENSVURP00010012149 ENSVURP00010012149 IKBKB IKBKB MAP3K14 MAP3K14 PIK3CB PIK3CB IL1B IL1B MAPK3 MAPK3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CSF1RUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (959 aa)
MITFBHLH domain-containing protein. (526 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (321 aa)
LOC114049642Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ENSVURP00010009787annotation not available (171 aa)
ENSVURP00010009777annotation not available (68 aa)
SYKUncharacterized protein. (639 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (607 aa)
CAMK4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (441 aa)
ENSVURP00010008190TPR_REGION domain-containing protein. (257 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (633 aa)
ENSVURP00010007417annotation not available (665 aa)
LOC114034206Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (665 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
CREB1Uncharacterized protein. (327 aa)
NCF1Uncharacterized protein. (390 aa)
NCF4Uncharacterized protein. (340 aa)
SPIBETS domain-containing protein. (288 aa)
ENSVURP00010005272ETS domain-containing protein. (271 aa)
ENSVURP00010004801Ig-like domain-containing protein. (237 aa)
IFNGR2Fibronectin type-III domain-containing protein. (357 aa)
IFNAR1Uncharacterized protein. (555 aa)
IFNAR2Uncharacterized protein. (509 aa)
ENSVURP00010004532Uncharacterized protein. (171 aa)
ENSVURP00010004522Uncharacterized protein. (68 aa)
IFNGR1Uncharacterized protein. (492 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
LOC114047099Uncharacterized protein. (406 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (535 aa)
BTKTyrosine-protein kinase. (659 aa)
TAB2Uncharacterized protein. (694 aa)
LOC114047681Ig-like domain-containing protein. (286 aa)
TNFTNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (232 aa)
LOC114047683Uncharacterized protein. (237 aa)
LCP2Lymphocyte cytosolic protein 2. (460 aa)
MAPK11Mitogen-activated protein kinase. (362 aa)
MAPK12Mitogen-activated protein kinase. (365 aa)
ENSVURP00010002081Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
NFKB2Uncharacterized protein. (929 aa)
RELARHD domain-containing protein. (538 aa)
FOSL1BZIP domain-containing protein. (311 aa)
LOC114042161Ig-like domain-containing protein. (238 aa)
BLNKSH2 domain-containing protein. (488 aa)
RELBRHD domain-containing protein. (511 aa)
MAP2K7Protein kinase domain-containing protein. (462 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (164 aa)
PIK3CDUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1075 aa)
STAT2Signal transducer and activator of transcription. (806 aa)
TYROBPTYRO protein tyrosine kinase binding protein. (105 aa)
FYNTyrosine-protein kinase. (537 aa)
IRF9Interferon regulatory factor 9. (411 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (565 aa)
ENSVURP00010029447Tyrosine-protein kinase. (1149 aa)
ENSVURP00010029419Tyrosine-protein kinase. (1180 aa)
MAPK10Mitogen-activated protein kinase. (449 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (349 aa)
ENSVURP00010028243annotation not available (232 aa)
ENSVURP00010027685annotation not available (288 aa)
IL1R1Uncharacterized protein. (561 aa)
NFKB1Uncharacterized protein. (1007 aa)
PPP3CASerine/threonine-protein phosphatase. (511 aa)
CYBACytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (191 aa)
NFKBIAANK_REP_REGION domain-containing protein. (321 aa)
FOSL2BZIP domain-containing protein. (325 aa)
NFATC1Nuclear factor of activated T cells 1. (814 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1212 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
LOC114053487IG domain-containing protein. (232 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (892 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
SQSTM1Uncharacterized protein. (445 aa)
PIK3R1Uncharacterized protein. (725 aa)
MAPK13Mitogen-activated protein kinase. (356 aa)
CALCRUncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (466 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
IKBKGCCHC NOA-type domain-containing protein. (575 aa)
NFATC2RHD domain-containing protein. (924 aa)
TNFRSF1AUncharacterized protein. (459 aa)
ENSVURP00010023958annotation not available (114 aa)
FOSBZIP domain-containing protein. (378 aa)
STAT1Signal transducer and activator of transcription. (750 aa)
MAP2K1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (393 aa)
LOC114024909Uncharacterized protein. (464 aa)
ENSVURP00010022479Uncharacterized protein. (114 aa)
ENSVURP00010022363annotation not available (408 aa)
TNFRSF11BTumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. (401 aa)
ENSVURP00010021762annotation not available (509 aa)
LOC114048474Uncharacterized protein. (502 aa)
GAB2PH domain-containing protein. (682 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1264 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
LOC114049642-2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (730 aa)
TNFRSF11ATNFR-Cys domain-containing protein. (671 aa)
ENSVURP00010019693Ig-like domain-containing protein. (124 aa)
JUNDJunD proto-oncogene, AP-1 transcription factor subunit. (307 aa)
PIK3R2Uncharacterized protein. (738 aa)
PTK6Tyrosine-protein kinase. (453 aa)
SRMSTyrosine-protein kinase. (514 aa)
PPP3CCSerine/threonine-protein phosphatase. (517 aa)
ENSVURP00010019380annotation not available (406 aa)
ENSVURP00010018742Ig-like domain-containing protein. (259 aa)
PPP3CBSerine/threonine-protein phosphatase. (520 aa)
CSF1Uncharacterized protein. (561 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (539 aa)
PPP3R1Uncharacterized protein. (170 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
JUNBBZIP domain-containing protein. (360 aa)
IFNB1Uncharacterized protein. (190 aa)
MAP2K6Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (334 aa)
ACP5Tartrate-resistant acid phosphatase type 5. (326 aa)
ENSVURP00010015483Uncharacterized protein. (422 aa)
GRB2Uncharacterized protein. (217 aa)
ENSVURP00010015465Ig-like domain-containing protein. (319 aa)
ENSVURP00010015457Uncharacterized protein. (268 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (540 aa)
NOX1NADPH oxidase 1. (587 aa)
LOC114051561Uncharacterized protein. (258 aa)
SOCS3Uncharacterized protein. (226 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
NCF2Uncharacterized protein. (526 aa)
SPI1ETS domain-containing protein. (341 aa)
TECTyrosine-protein kinase. (633 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (314 aa)
ENSVURP00010012149Integrin beta; Belongs to the integrin beta chain family. (761 aa)
IKBKBProtein kinase domain-containing protein. (757 aa)
MAP3K14Protein kinase domain-containing protein. (932 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1052 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (299 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
Your Current Organism:
Vombatus ursinus
NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat
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