STRINGSTRING
GUCY1A2 GUCY1A2 ENSVURP00010018147 ENSVURP00010018147 PDGFD PDGFD EGFR EGFR SRC SRC RAF1 RAF1 PRKCA PRKCA LOC114051339 LOC114051339 GEM GEM ENSVURP00010000165 ENSVURP00010000165 DRD1 DRD1 CDK1 CDK1 GNAQ GNAQ ADCY3 ADCY3 PTRHD1 PTRHD1 GRM1 GRM1 TUBB TUBB SOS1 SOS1 LOC114046825 LOC114046825 PRKG1 PRKG1 ENSVURP00010003713 ENSVURP00010003713 PDGFB PDGFB TUBB2A TUBB2A PLCB3 PLCB3 HRAS HRAS EGF EGF ENSVURP00010007025 ENSVURP00010007025 MAPK7 MAPK7 ADCY6 ADCY6 TUBB4B TUBB4B ENSVURP00010008472 ENSVURP00010008472 ENSVURP00010008481 ENSVURP00010008481 ENSVURP00010008488 ENSVURP00010008488 ADCY5 ADCY5 PLCB4 PLCB4 PLCB1 PLCB1 PDGFRB PDGFRB PLCB2 PLCB2 LPAR1 LPAR1 MAPK3 MAPK3 GJD2 GJD2 ITPR1 ITPR1 SOS2 SOS2 CSDE1 CSDE1 NRAS NRAS LOC114027938 LOC114027938 PRKACB PRKACB ENSVURP00010013724 ENSVURP00010013724 PDGFRA PDGFRA ENSVURP00010014386 ENSVURP00010014386 ENSVURP00010014393 ENSVURP00010014393 GNAI1 GNAI1 PDGFC PDGFC GUCY1B1 GUCY1B1 GUCY1A1 GUCY1A1 ADCY8 ADCY8 MAP3K2 MAP3K2 GRB2 GRB2 PRKCG PRKCG ADRB1 ADRB1 MAP2K2 MAP2K2 TUBB4A TUBB4A PRKACA PRKACA TUBA8 TUBA8 HTR2A HTR2A GJA1 GJA1 ADCY4 ADCY4 PRKG2 PRKG2 HTR2B HTR2B ENSVURP00010028769 ENSVURP00010028769 ENSVURP00010028552 ENSVURP00010028552 MAPK1 MAPK1 ADCY2 ADCY2 LOC114032238 LOC114032238 TUBB3 TUBB3 ADCY7 ADCY7 ENSVURP00010025478 ENSVURP00010025478 DRD2 DRD2 ENSVURP00010024629 ENSVURP00010024629 PRKACG PRKACG TUBB1 TUBB1 ENSVURP00010023297 ENSVURP00010023297 GNAI2 GNAI2 MAP2K5 MAP2K5 ADCY9 ADCY9 ENSVURP00010022760 ENSVURP00010022760 LOC114051918 LOC114051918 MAP2K1 MAP2K1 PRKCB PRKCB LOC114031783 LOC114031783 ENSVURP00010021504 ENSVURP00010021504 ENSVURP00010021292 ENSVURP00010021292 ITPR3 ITPR3 KRAS KRAS ITPR2 ITPR2 TJP1 TJP1 ENSVURP00010019784 ENSVURP00010019784 ENSVURP00010019760 ENSVURP00010019760 ADCY1 ADCY1 GNAI3 GNAI3 GNA11 GNA11 ENSVURP00010018459 ENSVURP00010018459
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GUCY1A2Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (729 aa)
ENSVURP00010018147annotation not available (1253 aa)
PDGFDPlatelet derived growth factor D; Belongs to the PDGF/VEGF growth factor family. (345 aa)
EGFRReceptor protein-tyrosine kinase. (1214 aa)
SRCTyrosine-protein kinase. (532 aa)
RAF1Uncharacterized protein. (667 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
LOC114051339Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (452 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (296 aa)
ENSVURP00010000165Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (410 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (448 aa)
CDK1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa)
GNAQG protein subunit alpha q. (343 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1150 aa)
PTRHD1Uncharacterized protein. (126 aa)
GRM1G_PROTEIN_RECEP_F3_4 domain-containing protein. (1206 aa)
TUBBTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (456 aa)
SOS1Uncharacterized protein. (1332 aa)
LOC114046825GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (303 aa)
PRKG1Protein kinase cGMP-dependent 1. (523 aa)
ENSVURP00010003713Cyclic nucleotide-binding domain-containing protein. (204 aa)
PDGFBPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (239 aa)
TUBB2ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1208 aa)
HRASUncharacterized protein. (189 aa)
EGFUncharacterized protein. (1191 aa)
ENSVURP00010007025Protein kinase domain-containing protein. (224 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (807 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1158 aa)
TUBB4BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
ENSVURP00010008472Tubulin domain-containing protein. (133 aa)
ENSVURP00010008481Tubulin domain-containing protein. (84 aa)
ENSVURP00010008488Tubulin domain-containing protein. (127 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1256 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1117 aa)
PDGFRBUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1101 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1187 aa)
LPAR1G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (366 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
GJD2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (322 aa)
ITPR1Uncharacterized protein. (2710 aa)
SOS2Uncharacterized protein. (1329 aa)
CSDE1Uncharacterized protein. (847 aa)
NRASUncharacterized protein. (189 aa)
LOC114027938GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (305 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (422 aa)
ENSVURP00010013724annotation not available (305 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1086 aa)
ENSVURP00010014386Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (376 aa)
ENSVURP00010014393annotation not available (376 aa)
GNAI1Uncharacterized protein. (359 aa)
PDGFCUncharacterized protein; Belongs to the PDGF/VEGF growth factor family. (345 aa)
GUCY1B1Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (619 aa)
GUCY1A1Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1253 aa)
MAP3K2Uncharacterized protein. (619 aa)
GRB2Uncharacterized protein. (217 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (703 aa)
ADRB1Adrenoceptor beta 1. (414 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
TUBB4ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
PRKACAUncharacterized protein; Belongs to the protein kinase superfamily. (352 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
HTR2AG_PROTEIN_RECEP_F1_2 domain-containing protein. (469 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1073 aa)
PRKG2cGMP-dependent protein kinase. (759 aa)
HTR2BG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (496 aa)
ENSVURP00010028769annotation not available (446 aa)
ENSVURP00010028552annotation not available (449 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (349 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1100 aa)
LOC114032238Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
TUBB3Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1081 aa)
ENSVURP00010025478annotation not available (211 aa)
DRD2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (443 aa)
ENSVURP00010024629annotation not available (446 aa)
PRKACGUncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
ENSVURP00010023297Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (603 aa)
GNAI2Uncharacterized protein. (355 aa)
MAP2K5Uncharacterized protein; Belongs to the protein kinase superfamily. (448 aa)
ADCY9Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1359 aa)
ENSVURP00010022760Uncharacterized protein. (125 aa)
LOC114051918PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (211 aa)
MAP2K1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (393 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (613 aa)
LOC114031783Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
ENSVURP00010021504Uncharacterized protein. (67 aa)
ENSVURP00010021292G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (459 aa)
ITPR3Uncharacterized protein. (2668 aa)
KRASUncharacterized protein. (189 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2705 aa)
TJP1Uncharacterized protein; Belongs to the MAGUK family. (1772 aa)
ENSVURP00010019784Uncharacterized protein. (218 aa)
ENSVURP00010019760Uncharacterized protein. (152 aa)
ADCY1Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1129 aa)
GNAI3Uncharacterized protein. (354 aa)
GNA11Uncharacterized protein. (359 aa)
ENSVURP00010018459GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (322 aa)
Your Current Organism:
Vombatus ursinus
NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat
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