STRINGSTRING
MAPK12 MAPK12 MAPK11 MAPK11 LCP2 LCP2 TNF TNF PTPN6 PTPN6 LOC114043698 LOC114043698 GRAP2 GRAP2 ENSVURP00010004342 ENSVURP00010004342 LOC114046276 LOC114046276 RELA RELA CD247 CD247 CD4 CD4 SOS1 SOS1 MAP2K7 MAP2K7 ZAP70 ZAP70 MAP2K2 MAP2K2 DLG1 DLG1 MAP3K8 MAP3K8 VAV1 VAV1 IFNG IFNG PIK3CD PIK3CD ENSVURP00010031546 ENSVURP00010031546 CDC42 CDC42 PAK4 PAK4 NFKBIB NFKBIB CDK4 CDK4 FYN FYN ENSVURP00010029556 ENSVURP00010029556 ENSVURP00010029551 ENSVURP00010029551 MAPK10 MAPK10 MAPK1 MAPK1 PDCD1 PDCD1 NFATC3 NFATC3 NFKB1 NFKB1 PPP3CA PPP3CA PAK3 PAK3 ENSVURP00010026737 ENSVURP00010026737 NFKBIA NFKBIA ENSVURP00010026635 ENSVURP00010026635 ENSVURP00010026623 ENSVURP00010026623 NFATC1 NFATC1 AKT2 AKT2 MAPK9 MAPK9 PIK3R1 PIK3R1 MAPK13 MAPK13 MAPK14 MAPK14 CARD11 CARD11 IKBKG IKBKG NFATC2 NFATC2 RHOA RHOA FOS FOS ENSVURP00010022993 ENSVURP00010022993 MAP2K1 MAP2K1 LOC114024909 LOC114024909 PAK1 PAK1 CD40LG CD40LG ENSVURP00010021023 ENSVURP00010021023 VAV3 VAV3 MAPK8 MAPK8 LOC114049642-2 LOC114049642-2 CHUK CHUK KRAS KRAS ENSVURP00010019784 ENSVURP00010019784 ENSVURP00010019760 ENSVURP00010019760 GSK3B GSK3B PRKCQ PRKCQ PIK3R2 PIK3R2 PTK6 PTK6 SRMS SRMS PPP3CC PPP3CC IL2 IL2 PLCG1 PLCG1 ENSVURP00010017930 ENSVURP00010017930 PPP3CB PPP3CB RAF1 RAF1 ENSVURP00010016607 ENSVURP00010016607 PPP3R1 PPP3R1 PIK3CA PIK3CA IL10 IL10 GRB2 GRB2 MALT1 MALT1 CD8B CD8B ENSVURP00010013628 ENSVURP00010013628 VAV2 VAV2 TEC TEC BCL10 BCL10 NRAS NRAS CSDE1 CSDE1 SOS2 SOS2 IKBKB IKBKB MAP3K14 MAP3K14 PIK3CB PIK3CB MAPK3 MAPK3 NCK1 NCK1 RASGRP1 RASGRP1 PAK6 PAK6 PAK2 PAK2 LOC114042481 LOC114042481 JUN JUN LOC114049642 LOC114049642 ENSVURP00010009759 ENSVURP00010009759 ENSVURP00010009758 ENSVURP00010009758 LOC114026713 LOC114026713 ENSVURP00010009713 ENSVURP00010009713 ENSVURP00010009260 ENSVURP00010009260 MAP3K7 MAP3K7 IL5 IL5 PTPRC PTPRC NFKBIE NFKBIE ITK ITK HRAS HRAS CD3D CD3D CD3G CD3G CD3E CD3E AKT1 AKT1 ICOS ICOS CTLA4 CTLA4 CD28 CD28
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK12Mitogen-activated protein kinase. (365 aa)
MAPK11Mitogen-activated protein kinase. (362 aa)
LCP2Lymphocyte cytosolic protein 2. (460 aa)
TNFTNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (232 aa)
PTPN6Protein tyrosine phosphatase non-receptor type 6. (578 aa)
LOC114043698Protein kinase domain-containing protein. (683 aa)
GRAP2GRB2 related adaptor protein 2. (336 aa)
ENSVURP00010004342Uncharacterized protein. (891 aa)
LOC114046276Cytoplasmic protein. (380 aa)
RELARHD domain-containing protein. (538 aa)
CD247Uncharacterized protein. (165 aa)
CD4Uncharacterized protein. (466 aa)
SOS1Uncharacterized protein. (1332 aa)
MAP2K7Protein kinase domain-containing protein. (462 aa)
ZAP70Tyrosine-protein kinase. (617 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (908 aa)
MAP3K8Protein kinase domain-containing protein. (467 aa)
VAV1Uncharacterized protein. (846 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (164 aa)
PIK3CDUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1075 aa)
ENSVURP00010031546CARD domain-containing protein. (217 aa)
CDC42Uncharacterized protein. (191 aa)
PAK4Non-specific serine/threonine protein kinase. (606 aa)
NFKBIBANK_REP_REGION domain-containing protein. (315 aa)
CDK4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (338 aa)
FYNTyrosine-protein kinase. (537 aa)
ENSVURP00010029556Ig-like domain-containing protein. (161 aa)
ENSVURP00010029551Ig-like domain-containing protein. (203 aa)
MAPK10Mitogen-activated protein kinase. (449 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (349 aa)
PDCD1Ig-like domain-containing protein. (266 aa)
NFATC3RHD domain-containing protein. (1087 aa)
NFKB1Uncharacterized protein. (1007 aa)
PPP3CASerine/threonine-protein phosphatase. (511 aa)
PAK3Uncharacterized protein. (576 aa)
ENSVURP00010026737DUF1968 domain-containing protein. (185 aa)
NFKBIAANK_REP_REGION domain-containing protein. (321 aa)
ENSVURP00010026635Ig-like domain-containing protein. (147 aa)
ENSVURP00010026623Ig-like domain-containing protein. (132 aa)
NFATC1Nuclear factor of activated T cells 1. (814 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
PIK3R1Uncharacterized protein. (725 aa)
MAPK13Mitogen-activated protein kinase. (356 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
CARD11Uncharacterized protein. (1151 aa)
IKBKGCCHC NOA-type domain-containing protein. (575 aa)
NFATC2RHD domain-containing protein. (924 aa)
RHOAUncharacterized protein. (193 aa)
FOSBZIP domain-containing protein. (378 aa)
ENSVURP00010022993Ig-like domain-containing protein. (152 aa)
MAP2K1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (393 aa)
LOC114024909Uncharacterized protein. (464 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (253 aa)
ENSVURP00010021023annotation not available (683 aa)
VAV3Uncharacterized protein. (873 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
LOC114049642-2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (730 aa)
KRASUncharacterized protein. (189 aa)
ENSVURP00010019784Uncharacterized protein. (218 aa)
ENSVURP00010019760Uncharacterized protein. (152 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (389 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (686 aa)
PIK3R2Uncharacterized protein. (738 aa)
PTK6Tyrosine-protein kinase. (453 aa)
SRMSTyrosine-protein kinase. (514 aa)
PPP3CCSerine/threonine-protein phosphatase. (517 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (141 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1279 aa)
ENSVURP00010017930Uncharacterized protein. (876 aa)
PPP3CBSerine/threonine-protein phosphatase. (520 aa)
RAF1Uncharacterized protein. (667 aa)
ENSVURP00010016607Ig-like domain-containing protein. (136 aa)
PPP3R1Uncharacterized protein. (170 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
IL10Uncharacterized protein. (206 aa)
GRB2Uncharacterized protein. (217 aa)
MALT1Uncharacterized protein. (820 aa)
CD8BIg-like domain-containing protein. (212 aa)
ENSVURP00010013628Ig-like domain-containing protein. (282 aa)
VAV2Vav guanine nucleotide exchange factor 2. (758 aa)
TECTyrosine-protein kinase. (633 aa)
BCL10CARD domain-containing protein. (238 aa)
NRASUncharacterized protein. (189 aa)
CSDE1Uncharacterized protein. (847 aa)
SOS2Uncharacterized protein. (1329 aa)
IKBKBProtein kinase domain-containing protein. (757 aa)
MAP3K14Protein kinase domain-containing protein. (932 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1052 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
NCK1Cytoplasmic protein. (377 aa)
RASGRP1RAS guanyl releasing protein 1. (761 aa)
PAK6Non-specific serine/threonine protein kinase. (730 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
LOC114042481CRIB domain-containing protein. (221 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (321 aa)
LOC114049642Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ENSVURP00010009759annotation not available (380 aa)
ENSVURP00010009758Protein kinase domain-containing protein. (364 aa)
LOC114026713Protein kinase domain-containing protein. (653 aa)
ENSVURP00010009713Uncharacterized protein. (252 aa)
ENSVURP00010009260Calponin-homology (CH) domain-containing protein. (88 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (607 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (138 aa)
PTPRCUncharacterized protein. (1300 aa)
NFKBIEANK_REP_REGION domain-containing protein. (360 aa)
ITKTyrosine-protein kinase. (620 aa)
HRASUncharacterized protein. (189 aa)
CD3DIg_4 domain-containing protein. (191 aa)
CD3GIg_4 domain-containing protein. (186 aa)
CD3EIGc2 domain-containing protein. (204 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ICOSIGv domain-containing protein. (203 aa)
CTLA4IGv domain-containing protein. (223 aa)
CD28IGv domain-containing protein. (221 aa)
Your Current Organism:
Vombatus ursinus
NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat
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