STRINGSTRING
TPH2 TPH2 SLC18A2 SLC18A2 ENSVURP00010031806 ENSVURP00010031806 PRKACA PRKACA CACNA1A CACNA1A CACNA1C CACNA1C KCND2 KCND2 GNB1 GNB1 HTR2A HTR2A HTR1D HTR1D ENSVURP00010030047 ENSVURP00010030047 LOC114052660 LOC114052660 ENSVURP00010030017 ENSVURP00010030017 LOC114040557 LOC114040557 ENSVURP00010029953 ENSVURP00010029953 ENSVURP00010029911 ENSVURP00010029911 HTR2B HTR2B LOC114045933 LOC114045933 KCNJ5 KCNJ5 MAPK1 MAPK1 ENSVURP00010028323 ENSVURP00010028323 CACNA1F CACNA1F HTR1A HTR1A ENSVURP00010025348 ENSVURP00010025348 LOC114023260 LOC114023260 GNGT1 GNGT1 HTR3B HTR3B HTR7 HTR7 HTR3A HTR3A PRKACG PRKACG GNAO1 GNAO1 GNAI2 GNAI2 ENSVURP00010022954 ENSVURP00010022954 LOC114024845 LOC114024845 ENSVURP00010022760 ENSVURP00010022760 MAP2K1 MAP2K1 LOC114052448 LOC114052448 PRKCB PRKCB ENSVURP00010022084 ENSVURP00010022084 ENSVURP00010021955 ENSVURP00010021955 GNG7 GNG7 ENSVURP00010021292 ENSVURP00010021292 ITPR3 ITPR3 ENSVURP00010020809 ENSVURP00010020809 ALOX5 ALOX5 KRAS KRAS ITPR2 ITPR2 GNG13 GNG13 ENSVURP00010019784 ENSVURP00010019784 ENSVURP00010019760 ENSVURP00010019760 HTR1F HTR1F PRKCA PRKCA BRAF BRAF GNAI3 GNAI3 PLA2G4C PLA2G4C HTR1B HTR1B DDC DDC CACNA1B CACNA1B GNG12 GNG12 RAF1 RAF1 ENSVURP00010017251 ENSVURP00010017251 LOC114023950 LOC114023950 GNAI1 GNAI1 ENSVURP00010016702 ENSVURP00010016702 CACNA1D CACNA1D GNB4 GNB4 ENSVURP00010016157 ENSVURP00010016157 PLA2G4A PLA2G4A PTGS2 PTGS2 PRKCG PRKCG LOC114037772 LOC114037772 TRPC1 TRPC1 GABRB3 GABRB3 PRKACB PRKACB GNG5 GNG5 NRAS NRAS CSDE1 CSDE1 ENSVURP00010012330 ENSVURP00010012330 SLC6A4 SLC6A4 ITPR1 ITPR1 GABRB1 GABRB1 HTR5A HTR5A ENSVURP00010011493 ENSVURP00010011493 MAPK3 MAPK3 LOC114047083 LOC114047083 SLC18A1 SLC18A1 PLCB2 PLCB2 LOC114036289 LOC114036289 ENSVURP00010010400 ENSVURP00010010400 LOC114036300 LOC114036300 GNGT2 GNGT2 PLCB1 PLCB1 PLCB4 PLCB4 JMJD7 JMJD7 PLA2G4B PLA2G4B PLA2G4E PLA2G4E PLA2G4D PLA2G4D PLA2G4F PLA2G4F ENSVURP00010008908 ENSVURP00010008908 ADCY5 ADCY5 TPH1 TPH1 APP APP KCNN2 KCNN2 HTR1E HTR1E LOC114031031 LOC114031031 RAPGEF3 RAPGEF3 GNG10 GNG10 KCNJ6 KCNJ6 HRAS HRAS GNB5 GNB5 PLCB3 PLCB3 ENSVURP00010005288 ENSVURP00010005288 CACNA1S CACNA1S ALOX12B ALOX12B ENSVURP00010004981 ENSVURP00010004981 LOC114050080 LOC114050080 GABRB2 GABRB2 ENSVURP00010004112 ENSVURP00010004112 MAOB MAOB MAOA MAOA ALOX12 ALOX12 ALOX15 ALOX15 KCNJ9 KCNJ9 GNG3 GNG3 GNB3 GNB3 DUSP1 DUSP1 GNB2 GNB2 HTR4 HTR4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TPH2Uncharacterized protein. (485 aa)
SLC18A2MFS domain-containing protein. (514 aa)
ENSVURP00010031806Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PRKACAUncharacterized protein; Belongs to the protein kinase superfamily. (352 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2485 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2052 aa)
KCND2BTB domain-containing protein; Belongs to the potassium channel family. (631 aa)
GNB1WD_REPEATS_REGION domain-containing protein. (340 aa)
HTR2AG_PROTEIN_RECEP_F1_2 domain-containing protein. (469 aa)
HTR1DG_PROTEIN_RECEP_F1_2 domain-containing protein. (379 aa)
ENSVURP00010030047Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (444 aa)
LOC114052660Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (453 aa)
ENSVURP00010030017Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (471 aa)
LOC114040557Uncharacterized protein; Belongs to the peptidase C14A family. (276 aa)
ENSVURP00010029953Uncharacterized protein; Belongs to the peptidase C14A family. (274 aa)
ENSVURP00010029911Uncharacterized protein; Belongs to the cytochrome P450 family. (493 aa)
HTR2BG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (496 aa)
LOC114045933Uncharacterized protein. (505 aa)
KCNJ5Uncharacterized protein. (418 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (349 aa)
ENSVURP00010028323annotation not available (70 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1862 aa)
HTR1AG_PROTEIN_RECEP_F1_2 domain-containing protein. (418 aa)
ENSVURP00010025348annotation not available (498 aa)
LOC114023260G protein gamma domain-containing protein. (121 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
HTR3B5-hydroxytryptamine receptor 3B; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (475 aa)
HTR7G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (454 aa)
HTR3A5-hydroxytryptamine receptor 3A; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (493 aa)
PRKACGUncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
GNAO1Uncharacterized protein. (354 aa)
GNAI2Uncharacterized protein. (355 aa)
ENSVURP00010022954Uncharacterized protein; Belongs to the cytochrome P450 family. (511 aa)
LOC114024845Uncharacterized protein; Belongs to the cytochrome P450 family. (515 aa)
ENSVURP00010022760Uncharacterized protein. (125 aa)
MAP2K1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (393 aa)
LOC114052448Uncharacterized protein; Belongs to the cytochrome P450 family. (498 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (613 aa)
ENSVURP00010022084annotation not available (572 aa)
ENSVURP00010021955annotation not available (594 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ENSVURP00010021292G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (459 aa)
ITPR3Uncharacterized protein. (2668 aa)
ENSVURP00010020809Uncharacterized protein. (238 aa)
ALOX5Uncharacterized protein. (674 aa)
KRASUncharacterized protein. (189 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2705 aa)
GNG13G protein subunit gamma 13. (69 aa)
ENSVURP00010019784Uncharacterized protein. (218 aa)
ENSVURP00010019760Uncharacterized protein. (152 aa)
HTR1F5-hydroxytryptamine receptor 1F. (366 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (741 aa)
GNAI3Uncharacterized protein. (354 aa)
PLA2G4CPLA2c domain-containing protein. (576 aa)
HTR1BG_PROTEIN_RECEP_F1_2 domain-containing protein. (386 aa)
DDCDopa decarboxylase. (490 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2353 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
RAF1Uncharacterized protein. (667 aa)
ENSVURP00010017251G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (420 aa)
LOC114023950Uncharacterized protein. (203 aa)
GNAI1Uncharacterized protein. (359 aa)
ENSVURP00010016702Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1962 aa)
GNB4WD_REPEATS_REGION domain-containing protein. (340 aa)
ENSVURP00010016157Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PLA2G4APhospholipase A2. (724 aa)
PTGS2EGF-like domain-containing protein. (608 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (703 aa)
LOC114037772G_PROTEIN_RECEP_F1_2 domain-containing protein. (372 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (786 aa)
GABRB3Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (473 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (422 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
NRASUncharacterized protein. (189 aa)
CSDE1Uncharacterized protein. (847 aa)
ENSVURP00010012330Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (630 aa)
ITPR1Uncharacterized protein. (2710 aa)
GABRB1Gamma-aminobutyric acid type A receptor beta1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (468 aa)
HTR5AG_PROTEIN_RECEP_F1_2 domain-containing protein. (357 aa)
ENSVURP00010011493EGF-like domain-containing protein. (572 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
LOC114047083EGF-like domain-containing protein. (594 aa)
SLC18A1MFS domain-containing protein. (522 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1187 aa)
LOC114036289Uncharacterized protein; Belongs to the cytochrome P450 family. (206 aa)
ENSVURP00010010400Uncharacterized protein. (378 aa)
LOC114036300Uncharacterized protein; Belongs to the cytochrome P450 family. (503 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1117 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
JMJD7JmjC domain-containing protein. (321 aa)
PLA2G4BPhospholipase A2. (786 aa)
PLA2G4EPhospholipase A2. (840 aa)
PLA2G4DPhospholipase A2. (811 aa)
PLA2G4FPhospholipase A2. (836 aa)
ENSVURP00010008908CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. (190 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1256 aa)
TPH1Uncharacterized protein. (444 aa)
APPBPTI/Kunitz inhibitor domain-containing protein. (751 aa)
KCNN2CaMBD domain-containing protein. (830 aa)
HTR1EG_PROTEIN_RECEP_F1_2 domain-containing protein. (365 aa)
LOC114031031Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
RAPGEF3Uncharacterized protein. (880 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (327 aa)
HRASUncharacterized protein. (189 aa)
GNB5WD_REPEATS_REGION domain-containing protein. (395 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1208 aa)
ENSVURP00010005288annotation not available (75 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1342 aa)
ALOX12BUncharacterized protein. (700 aa)
ENSVURP00010004981Lipoxygenase domain-containing protein. (116 aa)
LOC114050080Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GABRB2Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
ENSVURP00010004112Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
MAOBAmine oxidase. (520 aa)
MAOAAmine oxidase. (537 aa)
ALOX12Uncharacterized protein. (665 aa)
ALOX15Arachidonate 15-lipoxygenase. (618 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (393 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNB3WD_REPEATS_REGION domain-containing protein. (340 aa)
DUSP1Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (339 aa)
GNB2WD_REPEATS_REGION domain-containing protein. (340 aa)
HTR45-hydroxytryptamine receptor 4; Belongs to the G-protein coupled receptor 1 family. (375 aa)
Your Current Organism:
Vombatus ursinus
NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat
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