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| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1264 aa) |
| | ENSVURP00010021023 | annotation not available (683 aa) |
| | LOC114049642-2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | KRAS | Uncharacterized protein. (189 aa) |
| | ENSVURP00010019971 | PAS domain-containing protein. (1382 aa) |
| | ENSVURP00010019784 | Uncharacterized protein. (218 aa) |
| | ENSVURP00010019760 | Uncharacterized protein. (152 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (389 aa) |
| | ATP1B4 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (324 aa) |
| | RXRB | Retinoid X receptor beta. (472 aa) |
| | PIK3R2 | Uncharacterized protein. (738 aa) |
| | ENSVURP00010019160 | Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (124 aa) |
| | ENSVURP00010019151 | Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (135 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1279 aa) |
| | ENSVURP00010017759 | annotation not available (448 aa) |
| | ENSVURP00010017722 | SWIB domain-containing protein. (173 aa) |
| | SRC | Tyrosine-protein kinase. (532 aa) |
| | RAF1 | Uncharacterized protein. (667 aa) |
| | MED12 | Mediator complex subunit 12. (2158 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | MED27 | Mediator complex subunit 27. (172 aa) |
| | MED13 | Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2175 aa) |
| | SIN3A | HDAC_interact domain-containing protein. (1274 aa) |
| | PFKFB2 | 6PF2K domain-containing protein. (516 aa) |
| | ENSVURP00010015570 | MFS domain-containing protein. (201 aa) |
| | ENSVURP00010015561 | Uncharacterized protein. (304 aa) |
| | LOC114030664 | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (448 aa) |
| | MYH3 | Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa) |
| | LOC114034445 | Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (703 aa) |
| | MED12L | Mediator complex subunit 12 like. (1812 aa) |
| | LOC114034439 | Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1934 aa) |
| | MYH4 | Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1940 aa) |
| | MYH8 | Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa) |
| | ENSVURP00010014291 | annotation not available (318 aa) |
| | ENSVURP00010014276 | Uncharacterized protein. (318 aa) |
| | TSC2 | Rap-GAP domain-containing protein. (1807 aa) |
| | SIN3B | HDAC_interact domain-containing protein. (1097 aa) |
| | MED17 | Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (649 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (422 aa) |
| | NOTCH1 | Uncharacterized protein. (2538 aa) |
| | SLC9A1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (807 aa) |
| | ENSVURP00010009072 | Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (120 aa) |
| | RXRA | Uncharacterized protein. (483 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa) |
| | ATP2A1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1005 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1117 aa) |
| | LOC114049642 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | GATA4 | GATA binding protein 4. (450 aa) |
| | NOTCH2 | Uncharacterized protein. (2477 aa) |
| | RHEB | Uncharacterized protein. (184 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1187 aa) |
| | ATP1A1 | Sodium/potassium-transporting ATPase subunit alpha. (1021 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1052 aa) |
| | PLCD3 | Phosphoinositide phospholipase C. (819 aa) |
| | ACTG1 | Uncharacterized protein. (375 aa) |
| | ATP1B3 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (278 aa) |
| | HDAC3 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (428 aa) |
| | ENSVURP00010012149 | Integrin beta; Belongs to the integrin beta chain family. (761 aa) |
| | TBC1D4 | Rab-GAP TBC domain-containing protein. (1084 aa) |
| | ATP1A3 | Sodium/potassium-transporting ATPase subunit alpha. (1027 aa) |
| | CSDE1 | Uncharacterized protein. (847 aa) |
| | NRAS | Uncharacterized protein. (189 aa) |
| | HDAC1 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa) |
| | NCOA3 | Nuclear receptor coactivator. (1397 aa) |
| | NCOA1 | Nuclear receptor coactivator. (1444 aa) |
| | CASP9 | Uncharacterized protein; Belongs to the peptidase C14A family. (424 aa) |
| | ESR1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (589 aa) |
| | MED14 | Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1390 aa) |
| | EP300 | Uncharacterized protein. (2440 aa) |
| | ENSVURP00010002688 | Cation_ATPase_C domain-containing protein. (165 aa) |
| | PLCD4 | Phosphoinositide phospholipase C. (727 aa) |
| | ATP1A2 | Sodium/potassium-transporting ATPase subunit alpha. (1020 aa) |
| | LOC114043698 | Protein kinase domain-containing protein. (683 aa) |
| | ENSVURP00010003212 | Uncharacterized protein. (340 aa) |
| | ENSVURP00010003223 | Nuc_recep-AF1 domain-containing protein. (117 aa) |
| | ENSVURP00010003370 | Phosphoinositide phospholipase C. (1544 aa) |
| | ENSVURP00010004022 | Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (132 aa) |
| | ATP1B2 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (370 aa) |
| | ENSVURP00010005215 | annotation not available (1544 aa) |
| | ATP1B1 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (277 aa) |
| | RCAN2 | Uncharacterized protein. (198 aa) |
| | RCAN1 | Uncharacterized protein. (197 aa) |
| | ATP2A2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa) |
| | BAD | Uncharacterized protein. (180 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1208 aa) |
| | ENSVURP00010006355 | Uncharacterized protein. (66 aa) |
| | HRAS | Uncharacterized protein. (189 aa) |
| | MED13L | Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2218 aa) |
| | SLC16A2 | MFS domain-containing protein. (494 aa) |
| | THRA | Uncharacterized protein. (408 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | MED24 | Uncharacterized protein. (1016 aa) |
| | NOTCH4 | Uncharacterized protein. (1978 aa) |
| | PFKM | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (782 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1582 aa) |
| | NCOR1 | Nuclear receptor corepressor 1. (2462 aa) |
| | MED16 | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (831 aa) |
| | NOTCH3 | Uncharacterized protein. (2274 aa) |
| | MAP2K2 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa) |
| | CCND1 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (292 aa) |
| | ENSVURP00010032159 | FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (98 aa) |
| | ATP2A3 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (948 aa) |
| | PRKACA | Uncharacterized protein; Belongs to the protein kinase superfamily. (352 aa) |
| | PIK3CD | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1075 aa) |
| | MDM2 | Uncharacterized protein. (534 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2521 aa) |
| | PFKP | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (811 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | MED4 | Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (271 aa) |
| | RCAN3 | Uncharacterized protein. (241 aa) |
| | PLN | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa) |
| | HDAC2 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa) |
| | MYH7 | Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1915 aa) |
| | THRB | Uncharacterized protein. (476 aa) |
| | KAT2B | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (824 aa) |
| | KAT2A | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (833 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (349 aa) |
| | CTNNB1 | Catenin beta 1. (744 aa) |
| | ENSVURP00010027358 | PAS domain-containing protein. (1356 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | PIK3R1 | Uncharacterized protein. (725 aa) |
| | SLC2A1 | MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (491 aa) |
| | PRKACG | Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa) |
| | ACTB | Uncharacterized protein. (375 aa) |
| | HIF1A | Hypoxia inducible factor 1 subunit alpha. (814 aa) |
| | ITGAV | Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1063 aa) |
| | CREBBP | Uncharacterized protein. (2453 aa) |
| | STAT1 | Signal transducer and activator of transcription. (750 aa) |
| | FOXO1 | Forkhead box O1. (655 aa) |
| | MAP2K1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (393 aa) |
| | LOC114024909 | Uncharacterized protein. (464 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (613 aa) |
| | MED30 | Uncharacterized protein. (179 aa) |
| | PFKL | Uncharacterized protein. (726 aa) |
| | SLCO1C1 | Solute carrier organic anion transporter family member. (605 aa) |
| | PLCD1 | Phosphoinositide phospholipase C. (784 aa) |
