STRINGSTRING
PRKCG PRKCG MMP15 MMP15 CREB3L3 CREB3L3 ENSVURP00010032261 ENSVURP00010032261 PRKACA PRKACA LOC114037940 LOC114037940 LOC114050683-2 LOC114050683-2 CYP27B1 CYP27B1 ADCY4 ADCY4 TRPV5 TRPV5 ENSVURP00010029204 ENSVURP00010029204 LOC114045957-2 LOC114045957-2 MAPK1 MAPK1 SOST SOST ADCY2 ADCY2 PDE4D PDE4D MMP14 MMP14 ADCY7 ADCY7 KL KL LOC114050683 LOC114050683 CDKN1A CDKN1A ATF2 ATF2 GNA12 GNA12 CYP24A1 CYP24A1 PRKACG PRKACG RHOA RHOA FOS FOS GNAI2 GNAI2 MEF2C MEF2C ADCY9 ADCY9 ENSVURP00010022760 ENSVURP00010022760 MAP2K1 MAP2K1 PRKCB PRKCB ARRB1 ARRB1 LOC114049993 LOC114049993 ENSVURP00010021961 ENSVURP00010021961 ENSVURP00010021899 ENSVURP00010021899 ENSVURP00010021504 ENSVURP00010021504 ENSVURP00010021274 ENSVURP00010021274 ENSVURP00010021107 ENSVURP00010021107 ITPR3 ITPR3 LOC114045957 LOC114045957 ITPR2 ITPR2 JUND JUND PDE4C PDE4C RXRB RXRB ADCY1 ADCY1 PRKCA PRKCA BGLAP BGLAP GATA3 GATA3 BRAF BRAF MEF2D MEF2D GNAI3 GNAI3 GNA11 GNA11 PDE4B PDE4B CREB3L2 CREB3L2 ENSVURP00010018147 ENSVURP00010018147 ARHGEF11 ARHGEF11 MAFB MAFB EGFR EGFR MMP13 MMP13 RAF1 RAF1 BCL2 BCL2 LOC114023950 LOC114023950 GNAI1 GNAI1 PLD1 PLD1 ENSVURP00010016693 ENSVURP00010016693 GNA13 GNA13 ADCY8 ADCY8 SLC9A3R1 SLC9A3R1 PTH1R PTH1R SP1 SP1 CREB3L1 CREB3L1 PRKACB PRKACB FGFR1 FGFR1 HBEGF HBEGF TNFSF11 TNFSF11 ARHGEF1 ARHGEF1 EGR1 EGR1 ITPR1 ITPR1 MEF2A MEF2A MAPK3 MAPK3 PLCB2 PLCB2 AKAP13 AKAP13 PLCB1 PLCB1 FGF23 FGF23 PLCB4 PLCB4 LRP6 LRP6 RXRA RXRA ADCY5 ADCY5 SLC34A3 SLC34A3 ADCY6 ADCY6 CASR CASR VDR VDR MMP16 MMP16 ATF6B ATF6B PTHLH PTHLH LOC114023785 LOC114023785 PLCB3 PLCB3 LOC114023431 LOC114023431 CREB1 CREB1 RUNX2 RUNX2 PTH PTH ENSVURP00010004294 ENSVURP00010004294 GCM2 GCM2 ATF4 ATF4 ENSVURP00010003223 ENSVURP00010003223 ENSVURP00010003212 ENSVURP00010003212 ARRB2 ARRB2 PLD2 PLD2 PTRHD1 PTRHD1 ADCY3 ADCY3 GNAQ GNAQ MMP25 MMP25 SLC34A1 SLC34A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (703 aa)
MMP15Matrix metallopeptidase 15. (649 aa)
CREB3L3BZIP domain-containing protein. (468 aa)
ENSVURP00010032261Uncharacterized protein. (450 aa)
PRKACAUncharacterized protein; Belongs to the protein kinase superfamily. (352 aa)
LOC114037940NAC-A/B domain-containing protein. (215 aa)
LOC114050683-2Uncharacterized protein. (506 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (518 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1073 aa)
TRPV5Transient receptor potential cation channel subfamily V member 5; Belongs to the transient receptor (TC 1.A.4) family. (729 aa)
ENSVURP00010029204annotation not available (389 aa)
LOC114045957-2Uncharacterized protein. (630 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (349 aa)
SOSTCTCK domain-containing protein. (214 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1100 aa)
PDE4DPhosphodiesterase. (521 aa)
MMP14ZnMc domain-containing protein. (580 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1081 aa)
KLKlotho. (1052 aa)
LOC114050683BZIP domain-containing protein. (398 aa)
CDKN1AUncharacterized protein. (164 aa)
ATF2Uncharacterized protein. (577 aa)
GNA12Uncharacterized protein. (387 aa)
CYP24A1Uncharacterized protein; Belongs to the cytochrome P450 family. (514 aa)
PRKACGUncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
RHOAUncharacterized protein. (193 aa)
FOSBZIP domain-containing protein. (378 aa)
GNAI2Uncharacterized protein. (355 aa)
MEF2CMADS-box domain-containing protein. (483 aa)
ADCY9Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1359 aa)
ENSVURP00010022760Uncharacterized protein. (125 aa)
MAP2K1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (393 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (613 aa)
ARRB1Arrestin beta 1. (415 aa)
LOC114049993BZIP domain-containing protein. (389 aa)
ENSVURP00010021961G_PROTEIN_RECEP_F3_4 domain-containing protein. (849 aa)
ENSVURP00010021899G_PROTEIN_RECEP_F3_4 domain-containing protein. (799 aa)
ENSVURP00010021504Uncharacterized protein. (67 aa)
ENSVURP00010021274G_PROTEIN_RECEP_F3_4 domain-containing protein. (819 aa)
ENSVURP00010021107G_PROTEIN_RECEP_F3_4 domain-containing protein. (806 aa)
ITPR3Uncharacterized protein. (2668 aa)
LOC114045957Uncharacterized protein. (598 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2705 aa)
JUNDJunD proto-oncogene, AP-1 transcription factor subunit. (307 aa)
PDE4CPhosphodiesterase. (752 aa)
RXRBRetinoid X receptor beta. (472 aa)
ADCY1Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1129 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
BGLAPOsteocalcin; Binds strongly to apatite and calcium. (99 aa)
GATA3Uncharacterized protein. (444 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (741 aa)
MEF2DMADS-box domain-containing protein. (523 aa)
GNAI3Uncharacterized protein. (354 aa)
GNA11Uncharacterized protein. (359 aa)
PDE4BPhosphodiesterase. (560 aa)
CREB3L2BZIP domain-containing protein. (518 aa)
ENSVURP00010018147annotation not available (1253 aa)
ARHGEF11Uncharacterized protein. (1555 aa)
MAFBBZIP domain-containing protein. (311 aa)
EGFRReceptor protein-tyrosine kinase. (1214 aa)
MMP13ZnMc domain-containing protein. (480 aa)
RAF1Uncharacterized protein. (667 aa)
BCL2BCL2 apoptosis regulator. (256 aa)
LOC114023950Uncharacterized protein. (203 aa)
GNAI1Uncharacterized protein. (359 aa)
PLD1Phospholipase. (1035 aa)
ENSVURP00010016693Arrestin_N domain-containing protein. (260 aa)
GNA13Uncharacterized protein. (377 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1253 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (366 aa)
PTH1RUncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (584 aa)
SP1Sp1 transcription factor. (779 aa)
CREB3L1BZIP domain-containing protein. (526 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (422 aa)
FGFR1Fibroblast growth factor receptor. (822 aa)
HBEGFEGF-like domain-containing protein. (208 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (314 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (930 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (559 aa)
ITPR1Uncharacterized protein. (2710 aa)
MEF2AMADS-box domain-containing protein. (488 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1187 aa)
AKAP13A-kinase anchoring protein 13. (2880 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1117 aa)
FGF23Uncharacterized protein; Belongs to the heparin-binding growth factors family. (245 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
RXRAUncharacterized protein. (483 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1256 aa)
SLC34A3Solute carrier family 34 member 3. (567 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1158 aa)
CASRG_PROTEIN_RECEP_F3_4 domain-containing protein. (1070 aa)
VDRVitamin D receptor. (424 aa)
MMP16ZnMc domain-containing protein. (607 aa)
ATF6BActivating transcription factor 6 beta. (731 aa)
PTHLHUncharacterized protein. (185 aa)
LOC114023785Uncharacterized protein. (638 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1208 aa)
LOC114023431Uncharacterized protein. (692 aa)
CREB1Uncharacterized protein. (327 aa)
RUNX2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (494 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. (115 aa)
ENSVURP00010004294Uncharacterized protein. (136 aa)
GCM2GCM domain-containing protein. (484 aa)
ATF4BZIP domain-containing protein. (349 aa)
ENSVURP00010003223Nuc_recep-AF1 domain-containing protein. (117 aa)
ENSVURP00010003212Uncharacterized protein. (340 aa)
ARRB2Arrestin_C domain-containing protein. (436 aa)
PLD2Phospholipase. (934 aa)
PTRHD1Uncharacterized protein. (126 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1150 aa)
GNAQG protein subunit alpha q. (343 aa)
MMP25ZnMc domain-containing protein. (569 aa)
SLC34A1Uncharacterized protein. (642 aa)
Your Current Organism:
Vombatus ursinus
NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat
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