(48 nodes) Carbohydrate digestion and absorption network (Vombatus ursinus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	SLC2A2	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (519 aa)
	ENSVURP00010017654	Uncharacterized protein. (290 aa)
	SI	Sucrase-isomaltase. (1797 aa)
	HK1	Uncharacterized protein. (919 aa)
	HKDC1	Uncharacterized protein. (917 aa)
	ENSVURP00010019031	Peptidase S1 domain-containing protein. (229 aa)
	MGAM	Maltase-glucoamylase. (1743 aa)
	PIK3R2	Uncharacterized protein. (738 aa)
	ATP1B4	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (324 aa)
	ENSVURP00010020425	Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (675 aa)
	LOC114049642-2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	LOC114039152	Alpha-amylase. (511 aa)
	PRKCB	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (613 aa)
	LOC114024909	Uncharacterized protein. (464 aa)
	PIK3R1	Uncharacterized protein. (725 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	G6PC2	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa)
	G6PC	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
	SLC2A9	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (553 aa)
	TAS1R3	Taste 1 receptor member 3. (704 aa)
	PIK3CD	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1075 aa)
	SLC2A5	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (503 aa)
	SLC2A7	Solute carrier family 2 member 7; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (481 aa)
	ENSVURP00010032159	FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (98 aa)
	ATP1A3	Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
	ATP1B3	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (278 aa)
	HK2	Uncharacterized protein. (917 aa)
	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1052 aa)
	ATP1A1	Sodium/potassium-transporting ATPase subunit alpha. (1021 aa)
	G6PC3	acidPPc domain-containing protein. (378 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1187 aa)
	SLC5A1	Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (665 aa)
	HK3	Uncharacterized protein. (913 aa)
	ENSVURP00010002688	Cation_ATPase_C domain-containing protein. (165 aa)
	ATP1A2	Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
	ATP1B2	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
	ATP1B1	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (277 aa)
	SLC37A4	MFS domain-containing protein. (451 aa)
	PLCB3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1208 aa)
	ENSVURP00010006648	G_PROTEIN_RECEP_F3_4 domain-containing protein. (842 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	PLCB4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1117 aa)
	LOC114049642	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	CACNA1D	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1962 aa)
	GNAT3	Uncharacterized protein. (354 aa)
	TNIK	Uncharacterized protein. (1716 aa)

Your Current Organism:

Vombatus ursinus

NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	LOC114024909	ENSVURP00010006980	ENSVURP00010022548	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.839
AKT1	PIK3CA	ENSVURP00010006980	ENSVURP00010016429	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.874
AKT1	PIK3CB	ENSVURP00010006980	ENSVURP00010011407	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.862
AKT1	PIK3CD	ENSVURP00010006980	ENSVURP00010031571	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.862
AKT1	PIK3R1	ENSVURP00010006980	ENSVURP00010025486	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.847
AKT1	PIK3R2	ENSVURP00010006980	ENSVURP00010019570	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.841
AKT2	LOC114024909	ENSVURP00010026377	ENSVURP00010022548	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.931
AKT2	PIK3CA	ENSVURP00010026377	ENSVURP00010016429	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.946
AKT2	PIK3CB	ENSVURP00010026377	ENSVURP00010011407	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.941
AKT2	PIK3CD	ENSVURP00010026377	ENSVURP00010031571	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.941
AKT2	PIK3R1	ENSVURP00010026377	ENSVURP00010025486	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.935
AKT2	PIK3R2	ENSVURP00010026377	ENSVURP00010019570	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.932
ATP1A1	ATP1A2	ENSVURP00010010983	ENSVURP00010002729	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.923
ATP1A1	ATP1A3	ENSVURP00010010983	ENSVURP00010012458	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.923
ATP1A1	ATP1B1	ENSVURP00010010983	ENSVURP00010005224	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.995
ATP1A1	ATP1B2	ENSVURP00010010983	ENSVURP00010004255	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.985
ATP1A1	ATP1B3	ENSVURP00010010983	ENSVURP00010011780	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.985
ATP1A1	ATP1B4	ENSVURP00010010983	ENSVURP00010019619	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.985
ATP1A1	ENSVURP00010032159	ENSVURP00010010983	ENSVURP00010032159	Sodium/potassium-transporting ATPase subunit alpha.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.991
ATP1A2	ATP1A1	ENSVURP00010002729	ENSVURP00010010983	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.923