STRINGSTRING
SKAP2 SKAP2 MEFV MEFV ENSVURP00010000072 ENSVURP00010000072 RAC1 RAC1 MAP2K3 MAP2K3 FOS FOS RHOA RHOA ACTB ACTB ITGA4 ITGA4 ENSVURP00010024480 ENSVURP00010024480 ARHGEF28 ARHGEF28 NFATC2 NFATC2 ENSVURP00010024579 ENSVURP00010024579 ENSVURP00010024661 ENSVURP00010024661 ENSVURP00010024670 ENSVURP00010024670 ENSVURP00010024679 ENSVURP00010024679 IKBKG IKBKG MAPK14 MAPK14 MAPK13 MAPK13 WIPF1 WIPF1 LOC114032095 LOC114032095 IL18 IL18 PIK3R1 PIK3R1 SKAP2-2 SKAP2-2 MAPK9 MAPK9 ENSVURP00010025860 ENSVURP00010025860 ENSVURP00010025906 ENSVURP00010025906 ENSVURP00010026056 ENSVURP00010026056 AKT2 AKT2 ENSVURP00010026384 ENSVURP00010026384 NFATC1 NFATC1 ENSVURP00010026623 ENSVURP00010026623 ENSVURP00010026635 ENSVURP00010026635 ELMO2 ELMO2 NFKBIA NFKBIA ENSVURP00010026737 ENSVURP00010026737 NFKB1 NFKB1 NFATC3 NFATC3 IRAK1 IRAK1 CRKL CRKL MAPK1 MAPK1 RHOG RHOG MAPK10 MAPK10 ENSVURP00010029551 ENSVURP00010029551 ENSVURP00010029556 ENSVURP00010029556 BCAR1 BCAR1 ENSVURP00010030137 ENSVURP00010030137 LOC114031801 LOC114031801 CDC42 CDC42 WASL WASL ITGB1 ITGB1 PIK3CD PIK3CD TBK1 TBK1 PKN1 PKN1 DOCK1 DOCK1 VAV1 VAV1 TICAM1 TICAM1 MAP2K2 MAP2K2 ENSVURP00010032428 ENSVURP00010032428 ZAP70 ZAP70 MAP2K7 MAP2K7 LOC114039754 LOC114039754 ENSVURP00010032616 ENSVURP00010032616 LOC114024909 LOC114024909 MAP2K1 MAP2K1 ENSVURP00010022993 ENSVURP00010022993 ENSVURP00010021078 ENSVURP00010021078 ELMO1 ELMO1 VAV3 VAV3 MAPK8 MAPK8 MAP2K4 MAP2K4 LOC114049642-2 LOC114049642-2 CHUK CHUK LOC114047389-2 LOC114047389-2 ENSVURP00010020166 ENSVURP00010020166 ENSVURP00010019798 ENSVURP00010019798 GSK3B GSK3B PIK3R2 PIK3R2 IL2 IL2 ENSVURP00010019098 ENSVURP00010019098 LOC114043178 LOC114043178 LOC114030733 LOC114030733 LPXN LPXN PLCG1 PLCG1 ENSVURP00010017927 ENSVURP00010017927 ENSVURP00010017912 ENSVURP00010017912 IRF3 IRF3 ENSVURP00010017823 ENSVURP00010017823 SRC SRC ACTR2 ACTR2 RPS6KA6 RPS6KA6 ENSVURP00010016607 ENSVURP00010016607 PIK3CA PIK3CA LOC114040382-2 LOC114040382-2 LOC114040382 LOC114040382 ROCK2 ROCK2 IFNB1 IFNB1 LOC114023983 LOC114023983 MAP2K6 MAP2K6 IL10 IL10 LOC114043334 LOC114043334 MYD88 MYD88 RPS6KA3 RPS6KA3 TRAF6 TRAF6 LOC114030683 LOC114030683 LOC114040819 LOC114040819 LOC114040884 LOC114040884 PYDC1 PYDC1 RPS6KA2 RPS6KA2 CD8B CD8B ENSVURP00010013628 ENSVURP00010013628 VAV2 VAV2 WAS WAS ENSVURP00010013359 ENSVURP00010013359 CXCL8 CXCL8 BAIAP2 BAIAP2 ARF6 ARF6 ARHGEF1 ARHGEF1 IKBKB IKBKB ACTG1 ACTG1 PIK3CB PIK3CB IL1B IL1B MAPK3 MAPK3 LOC114031332 LOC114031332 ACTR3B ACTR3B ITGA5 ITGA5 JUN JUN GIT2 GIT2 LOC114049642 LOC114049642 ACTR3 ACTR3 ENSVURP00010009713 ENSVURP00010009713 PIP5K1B PIP5K1B WASF2 WASF2 ENSVURP00010009260 ENSVURP00010009260 RPS6KA1 RPS6KA1 MAP3K7 MAP3K7 PXN PXN TRAF2 TRAF2 AKT1 AKT1 WIPF2 WIPF2 LOC114047389 LOC114047389 ENSVURP00010005671 ENSVURP00010005671 RAC2 RAC2 LIMK1 LIMK1 IRAK4 IRAK4 ARHGEF12 ARHGEF12 FN1 FN1 TAB1 TAB1 LOC114050566 LOC114050566 TAB2 TAB2 TNF TNF LCP2 LCP2 MAPK11 MAPK11 MAPK12 MAPK12 ENSVURP00010002225 ENSVURP00010002225 CD4 CD4 RELA RELA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SKAP2PH domain-containing protein. (377 aa)
MEFVUncharacterized protein. (841 aa)
ENSVURP00010000072Ig-like domain-containing protein. (117 aa)
RAC1Uncharacterized protein. (211 aa)
MAP2K3Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (337 aa)
FOSBZIP domain-containing protein. (378 aa)
RHOAUncharacterized protein. (193 aa)
ACTBUncharacterized protein. (375 aa)
ITGA4Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1029 aa)
ENSVURP00010024480Uncharacterized protein. (198 aa)
ARHGEF28Uncharacterized protein. (1718 aa)
NFATC2RHD domain-containing protein. (924 aa)
ENSVURP00010024579annotation not available (577 aa)
ENSVURP00010024661FERM domain-containing protein. (121 aa)
ENSVURP00010024670Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (455 aa)
ENSVURP00010024679Focal_AT domain-containing protein. (115 aa)
IKBKGCCHC NOA-type domain-containing protein. (575 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAPK13Mitogen-activated protein kinase. (356 aa)
WIPF1WH2 domain-containing protein. (506 aa)
LOC114032095Uncharacterized protein. (208 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (198 aa)
PIK3R1Uncharacterized protein. (725 aa)
SKAP2-2Uncharacterized protein. (371 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
ENSVURP00010025860Ig-like domain-containing protein. (154 aa)
ENSVURP00010025906annotation not available (211 aa)
ENSVURP00010026056annotation not available (983 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ENSVURP00010026384annotation not available (215 aa)
NFATC1Nuclear factor of activated T cells 1. (814 aa)
ENSVURP00010026623Ig-like domain-containing protein. (132 aa)
ENSVURP00010026635Ig-like domain-containing protein. (147 aa)
ELMO2ELMO domain-containing protein. (722 aa)
NFKBIAANK_REP_REGION domain-containing protein. (321 aa)
ENSVURP00010026737DUF1968 domain-containing protein. (185 aa)
NFKB1Uncharacterized protein. (1007 aa)
NFATC3RHD domain-containing protein. (1087 aa)
IRAK1Protein kinase domain-containing protein. (727 aa)
CRKLUncharacterized protein. (303 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (349 aa)
RHOGUncharacterized protein. (191 aa)
MAPK10Mitogen-activated protein kinase. (449 aa)
ENSVURP00010029551Ig-like domain-containing protein. (203 aa)
ENSVURP00010029556Ig-like domain-containing protein. (161 aa)
BCAR1SH3 domain-containing protein. (928 aa)
ENSVURP00010030137Uncharacterized protein. (245 aa)
LOC114031801Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1355 aa)
CDC42Uncharacterized protein. (191 aa)
WASLWASP like actin nucleation promoting factor. (462 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (799 aa)
PIK3CDUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1075 aa)
TBK1Protein kinase domain-containing protein. (729 aa)
PKN1Uncharacterized protein. (1023 aa)
DOCK1Uncharacterized protein; Belongs to the DOCK family. (1772 aa)
VAV1Uncharacterized protein. (846 aa)
TICAM1TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (702 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
ENSVURP00010032428PIPK domain-containing protein. (604 aa)
ZAP70Tyrosine-protein kinase. (617 aa)
MAP2K7Protein kinase domain-containing protein. (462 aa)
LOC114039754Ig-like domain-containing protein. (283 aa)
ENSVURP00010032616Ig-like domain-containing protein. (137 aa)
LOC114024909Uncharacterized protein. (464 aa)
MAP2K1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (393 aa)
ENSVURP00010022993Ig-like domain-containing protein. (152 aa)
ENSVURP00010021078annotation not available (192 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
VAV3Uncharacterized protein. (873 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
MAP2K4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (402 aa)
LOC114049642-2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (730 aa)
LOC114047389-2TIR domain-containing protein; Belongs to the Toll-like receptor family. (881 aa)
ENSVURP00010020166Ig-like domain-containing protein. (154 aa)
ENSVURP00010019798annotation not available (145 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (389 aa)
PIK3R2Uncharacterized protein. (738 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (141 aa)
ENSVURP00010019098Ig-like domain-containing protein. (154 aa)
LOC114043178PIPK domain-containing protein. (577 aa)
LOC114030733Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1043 aa)
LPXNUncharacterized protein. (382 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1279 aa)
ENSVURP00010017927Uncharacterized protein. (377 aa)
ENSVURP00010017912Ig-like domain-containing protein. (189 aa)
IRF3IRF tryptophan pentad repeat domain-containing protein. (412 aa)
ENSVURP00010017823Ig-like domain-containing protein. (154 aa)
SRCTyrosine-protein kinase. (532 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (398 aa)
RPS6KA6Non-specific serine/threonine protein kinase. (714 aa)
ENSVURP00010016607Ig-like domain-containing protein. (136 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC114040382-2Uncharacterized protein. (162 aa)
LOC114040382Uncharacterized protein. (140 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
IFNB1Uncharacterized protein. (190 aa)
LOC114023983Uncharacterized protein. (191 aa)
MAP2K6Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (334 aa)
IL10Uncharacterized protein. (206 aa)
LOC114043334C-C motif chemokine. (145 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (318 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (540 aa)
LOC114030683Uncharacterized protein. (983 aa)
LOC114040819Uncharacterized protein. (200 aa)
LOC114040884Uncharacterized protein. (196 aa)
PYDC1Pyrin domain-containing protein. (89 aa)
RPS6KA2Ribosomal protein S6 kinase. (733 aa)
CD8BIg-like domain-containing protein. (212 aa)
ENSVURP00010013628Ig-like domain-containing protein. (282 aa)
VAV2Vav guanine nucleotide exchange factor 2. (758 aa)
WASUncharacterized protein. (494 aa)
ENSVURP00010013359Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1296 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (145 aa)
BAIAP2Uncharacterized protein. (543 aa)
ARF6Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (175 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (930 aa)
IKBKBProtein kinase domain-containing protein. (757 aa)
ACTG1Uncharacterized protein. (375 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1052 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (299 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
LOC114031332Uncharacterized protein. (192 aa)
ACTR3BUncharacterized protein; Belongs to the actin family. (418 aa)
ITGA5Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1106 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (321 aa)
GIT2Uncharacterized protein. (759 aa)
LOC114049642Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ACTR3Uncharacterized protein; Belongs to the actin family. (418 aa)
ENSVURP00010009713Uncharacterized protein. (252 aa)
PIP5K1BPIPK domain-containing protein. (539 aa)
WASF2WH2 domain-containing protein. (499 aa)
ENSVURP00010009260Calponin-homology (CH) domain-containing protein. (88 aa)
RPS6KA1Ribosomal protein S6 kinase. (753 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (607 aa)
PXNUncharacterized protein; Belongs to the paxillin family. (559 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (633 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
WIPF2WH2 domain-containing protein. (350 aa)
LOC114047389TIR domain-containing protein; Belongs to the Toll-like receptor family. (832 aa)
ENSVURP00010005671Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (757 aa)
RAC2Uncharacterized protein. (306 aa)
LIMK1Uncharacterized protein. (655 aa)
IRAK4Protein kinase domain-containing protein. (460 aa)
ARHGEF12Uncharacterized protein. (1539 aa)
FN1Uncharacterized protein. (2476 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (535 aa)
LOC114050566Uncharacterized protein. (215 aa)
TAB2Uncharacterized protein. (694 aa)
TNFTNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (232 aa)
LCP2Lymphocyte cytosolic protein 2. (460 aa)
MAPK11Mitogen-activated protein kinase. (362 aa)
MAPK12Mitogen-activated protein kinase. (365 aa)
ENSVURP00010002225Uncharacterized protein. (414 aa)
CD4Uncharacterized protein. (466 aa)
RELARHD domain-containing protein. (538 aa)
Your Current Organism:
Vombatus ursinus
NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat
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