STRINGSTRING
MAP2K2 MAP2K2 ENSVURP00010000102 ENSVURP00010000102 ENSVURP00010000112 ENSVURP00010000112 CLDN6 CLDN6 ENSVURP00010000671 ENSVURP00010000671 LOC114050697 LOC114050697 ENSVURP00010001316 ENSVURP00010001316 LOC114039318 LOC114039318 FIS1 FIS1 CASP9 CASP9 RELA RELA PPP2R2A PPP2R2A E2F3 E2F3 YWHAB YWHAB LOC114026424 LOC114026424 SOS1 SOS1 TNF TNF CLDN7 CLDN7 YWHAG YWHAG TP53 TP53 IFNAR2 IFNAR2 IFNAR1 IFNAR1 ENSVURP00010004866 ENSVURP00010004866 OAS1 OAS1 CLDN3 CLDN3 CLDN4 CLDN4 ENSVURP00010005502 ENSVURP00010005502 TRAF3 TRAF3 OAS2 OAS2 RIPK1 RIPK1 BAD BAD ENSVURP00010006355 ENSVURP00010006355 HRAS HRAS ENSVURP00010006520 ENSVURP00010006520 EGF EGF ENSVURP00010006971 ENSVURP00010006971 AKT1 AKT1 LOC114048347 LOC114048347 LOC114048343 LOC114048343 LOC114048351 LOC114048351 LOC114034206 LOC114034206 FASLG FASLG ENSVURP00010007417 ENSVURP00010007417 TRAF2 TRAF2 DDX58 DDX58 TLR3 TLR3 CLDN14 CLDN14 CLDN17 CLDN17 ENSVURP00010008800 ENSVURP00010008800 CLDN8 CLDN8 ENSVURP00010008908 ENSVURP00010008908 YWHAZ YWHAZ LOC114024560 LOC114024560 LOC114024333 LOC114024333 ENSVURP00010009165 ENSVURP00010009165 RXRA RXRA PPP2CA PPP2CA LOC114049642 LOC114049642 LOC114034312 LOC114034312 EIF2AK3 EIF2AK3 LOC114037676 LOC114037676 EIF3E EIF3E ENSVURP00010010742 ENSVURP00010010742 ENSVURP00010010745 ENSVURP00010010745 YWHAE YWHAE EIF2AK4 EIF2AK4 ENSVURP00010010935 ENSVURP00010010935 CLDN18 CLDN18 PPP2R2B PPP2R2B MAPK3 MAPK3 CASP8 CASP8 CFLAR CFLAR PIK3CB PIK3CB PPP2R1A PPP2R1A IKBKB IKBKB SOS2 SOS2 LDLR LDLR CSDE1 CSDE1 NRAS NRAS ENSVURP00010012903 ENSVURP00010012903 RNASEL RNASEL ENSVURP00010013115 ENSVURP00010013115 NR1H3 NR1H3 ENSVURP00010013232 ENSVURP00010013232 RSAD2 RSAD2 SOCS3 SOCS3 PPP2R2D PPP2R2D ENSVURP00010015181 ENSVURP00010015181 LOC114030664 LOC114030664 TRAF6 TRAF6 LOC114040367 LOC114040367 GRB2 GRB2 PPP2CB PPP2CB ENSVURP00010015764 ENSVURP00010015764 CD81 CD81 CLDN23 CLDN23 MAVS MAVS IKBKE IKBKE LOC114040899 LOC114040899 IFNB1 IFNB1 ENSVURP00010016304 ENSVURP00010016304 ENSVURP00010016345 ENSVURP00010016345 PIK3CA PIK3CA LOC114023950 LOC114023950 BAX BAX CLDN11 CLDN11 RAF1 RAF1 ENSVURP00010017685 ENSVURP00010017685 ENSVURP00010017759 ENSVURP00010017759 IRF3 IRF3 EGFR EGFR CLDN2 CLDN2 BRAF BRAF ENSVURP00010019348 ENSVURP00010019348 PIK3R2 PIK3R2 GSK3B GSK3B ENSVURP00010019760 ENSVURP00010019760 ENSVURP00010019784 ENSVURP00010019784 ENSVURP00010019921 ENSVURP00010019921 KRAS KRAS CHUK CHUK LOC114049642-2 LOC114049642-2 YWHAQ YWHAQ BAK1 BAK1 EIF2AK2 EIF2AK2 LOC114024909 LOC114024909 MAP2K1 MAP2K1 ENSVURP00010022786 ENSVURP00010022786 STAT1 STAT1 LOC114052230 LOC114052230 PIAS1 PIAS1 ENSVURP00010023494 ENSVURP00010023494 TNFRSF1A TNFRSF1A OCLN OCLN LOC114031473 LOC114031473 LOC114026201 LOC114026201 ENSVURP00010024490 ENSVURP00010024490 LOC114026200 LOC114026200 LOC114026146 LOC114026146 CLDN25 CLDN25 IKBKG IKBKG E2F1 E2F1 CDKN1A CDKN1A PIK3R1 PIK3R1 PPP2R1B PPP2R1B ENSVURP00010025815 ENSVURP00010025815 ENSVURP00010025884 ENSVURP00010025884 AKT2 AKT2 NFKBIA NFKBIA NFKB1 NFKB1 ENSVURP00010028091 ENSVURP00010028091 PSME3 PSME3 TRADD TRADD CTNNB1 CTNNB1 MAPK1 MAPK1 STAT3 STAT3 PPP2R2C PPP2R2C ENSVURP00010029419 ENSVURP00010029419 ENSVURP00010029447 ENSVURP00010029447 CDK6 CDK6 IRF9 IRF9 ENSVURP00010029953 ENSVURP00010029953 LOC114040557 LOC114040557 CDK4 CDK4 E2F2 E2F2 CLDN1 CLDN1 CLDN16 CLDN16 EIF2S1 EIF2S1 RB1 RB1 STAT2 STAT2 CDK2 CDK2 CLDN10 CLDN10 BID BID APAF1 APAF1 PIK3CD PIK3CD IFNG IFNG TBK1 TBK1 PPARA PPARA LOC114038574 LOC114038574 ENSVURP00010031982 ENSVURP00010031982 FADD FADD ENSVURP00010032211 ENSVURP00010032211 CCND1 CCND1 TICAM1 TICAM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
ENSVURP0001000010214_3_3 domain-containing protein; Belongs to the 14-3-3 family. (231 aa)
ENSVURP00010000112annotation not available (231 aa)
CLDN6Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (281 aa)
ENSVURP00010000671Uncharacterized protein. (588 aa)
LOC114050697Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ENSVURP00010001316Uncharacterized protein. (192 aa)
LOC114039318Uncharacterized protein. (186 aa)
FIS1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
CASP9Uncharacterized protein; Belongs to the peptidase C14A family. (424 aa)
RELARHD domain-containing protein. (538 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (446 aa)
E2F3E2F_TDP domain-containing protein. (460 aa)
YWHAB14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (263 aa)
LOC114026424Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
SOS1Uncharacterized protein. (1332 aa)
TNFTNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (232 aa)
CLDN7Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
YWHAG14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (247 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (370 aa)
IFNAR2Uncharacterized protein. (509 aa)
IFNAR1Uncharacterized protein. (555 aa)
ENSVURP0001000486614_3_3 domain-containing protein; Belongs to the 14-3-3 family. (125 aa)
OAS125A_SYNTH_3 domain-containing protein. (344 aa)
CLDN3Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (221 aa)
CLDN4Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
ENSVURP0001000550225A_SYNTH_3 domain-containing protein. (450 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa)
OAS2Uncharacterized protein. (711 aa)
RIPK1Uncharacterized protein. (719 aa)
BADUncharacterized protein. (180 aa)
ENSVURP00010006355Uncharacterized protein. (66 aa)
HRASUncharacterized protein. (189 aa)
ENSVURP00010006520IRF tryptophan pentad repeat domain-containing protein. (490 aa)
EGFUncharacterized protein. (1191 aa)
ENSVURP00010006971Uncharacterized protein. (180 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
LOC114048347Uncharacterized protein. (186 aa)
LOC114048343Uncharacterized protein. (182 aa)
LOC114048351Uncharacterized protein. (187 aa)
LOC114034206Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (665 aa)
FASLGTNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (280 aa)
ENSVURP00010007417annotation not available (665 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (633 aa)
DDX58Uncharacterized protein. (931 aa)
TLR3TIR domain-containing protein; Belongs to the Toll-like receptor family. (905 aa)
CLDN14Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (235 aa)
CLDN17Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (223 aa)
ENSVURP00010008800Uncharacterized protein. (186 aa)
CLDN8Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa)
ENSVURP00010008908CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. (190 aa)
YWHAZ14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa)
LOC114024560Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
LOC114024333Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
ENSVURP0001000916514_3_3 domain-containing protein; Belongs to the 14-3-3 family. (212 aa)
RXRAUncharacterized protein. (483 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
LOC114049642Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
LOC114034312Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
EIF2AK3Protein kinase domain-containing protein. (1005 aa)
LOC114037676Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
EIF3EEukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (352 aa)
ENSVURP00010010742Uncharacterized protein. (153 aa)
ENSVURP00010010745eIF3_N domain-containing protein. (55 aa)
YWHAE14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (255 aa)
EIF2AK4Uncharacterized protein. (1530 aa)
ENSVURP00010010935RWD domain-containing protein. (146 aa)
CLDN18Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (253 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (443 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
CASP8Uncharacterized protein; Belongs to the peptidase C14A family. (471 aa)
CFLARUncharacterized protein; Belongs to the peptidase C14A family. (485 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1052 aa)
PPP2R1AUncharacterized protein. (589 aa)
IKBKBProtein kinase domain-containing protein. (757 aa)
SOS2Uncharacterized protein. (1329 aa)
LDLRUncharacterized protein. (864 aa)
CSDE1Uncharacterized protein. (847 aa)
NRASUncharacterized protein. (189 aa)
ENSVURP00010012903SCY domain-containing protein. (105 aa)
RNASELUncharacterized protein. (713 aa)
ENSVURP00010013115Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (103 aa)
NR1H3Uncharacterized protein. (459 aa)
ENSVURP00010013232MARVEL domain-containing protein. (487 aa)
RSAD2Elp3 domain-containing protein. (363 aa)
SOCS3Uncharacterized protein. (226 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (443 aa)
ENSVURP00010015181Uncharacterized protein. (100 aa)
LOC114030664Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (448 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (540 aa)
LOC114040367Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
GRB2Uncharacterized protein. (217 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
ENSVURP00010015764annotation not available (211 aa)
CD81Uncharacterized protein; Belongs to the tetraspanin (TM4SF) family. (299 aa)
CLDN23Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (277 aa)
MAVSCARD_2 domain-containing protein. (488 aa)
IKBKEProtein kinase domain-containing protein. (793 aa)
LOC114040899Uncharacterized protein. (179 aa)
IFNB1Uncharacterized protein. (190 aa)
ENSVURP00010016304Uncharacterized protein; Belongs to the CD36 family. (379 aa)
ENSVURP00010016345annotation not available (379 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC114023950Uncharacterized protein. (203 aa)
BAXUncharacterized protein. (200 aa)
CLDN11Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa)
RAF1Uncharacterized protein. (667 aa)
ENSVURP00010017685Uncharacterized protein. (102 aa)
ENSVURP00010017759annotation not available (448 aa)
IRF3IRF tryptophan pentad repeat domain-containing protein. (412 aa)
EGFRReceptor protein-tyrosine kinase. (1214 aa)
CLDN2Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (231 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (741 aa)
ENSVURP00010019348Uncharacterized protein. (196 aa)
PIK3R2Uncharacterized protein. (738 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (389 aa)
ENSVURP00010019760Uncharacterized protein. (152 aa)
ENSVURP00010019784Uncharacterized protein. (218 aa)
ENSVURP0001001992114_3_3 domain-containing protein; Belongs to the 14-3-3 family. (96 aa)
KRASUncharacterized protein. (189 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (730 aa)
LOC114049642-2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
YWHAQ14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa)
BAK1Uncharacterized protein. (204 aa)
EIF2AK2Uncharacterized protein. (652 aa)
LOC114024909Uncharacterized protein. (464 aa)
MAP2K1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (393 aa)
ENSVURP00010022786Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (135 aa)
STAT1Signal transducer and activator of transcription. (750 aa)
LOC114052230Protein kinase domain-containing protein. (715 aa)
PIAS1Uncharacterized protein. (651 aa)
ENSVURP00010023494eIF3_N domain-containing protein; Belongs to the eIF-3 subunit E family. (187 aa)
TNFRSF1AUncharacterized protein. (459 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (515 aa)
LOC114031473Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa)
LOC114026201Uncharacterized protein. (432 aa)
ENSVURP00010024490Uncharacterized protein. (485 aa)
LOC114026200Uncharacterized protein. (480 aa)
LOC114026146Uncharacterized protein. (481 aa)
CLDN25Uncharacterized protein. (229 aa)
IKBKGCCHC NOA-type domain-containing protein. (575 aa)
E2F1E2F transcription factor 1. (431 aa)
CDKN1AUncharacterized protein. (164 aa)
PIK3R1Uncharacterized protein. (725 aa)
PPP2R1BUncharacterized protein. (662 aa)
ENSVURP00010025815annotation not available (715 aa)
ENSVURP00010025884annotation not available (588 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
NFKBIAANK_REP_REGION domain-containing protein. (321 aa)
NFKB1Uncharacterized protein. (1007 aa)
ENSVURP00010028091eIF3_N domain-containing protein; Belongs to the eIF-3 subunit E family. (228 aa)
PSME3Proteasome activator subunit 3. (265 aa)
TRADDDeath domain-containing protein. (313 aa)
CTNNB1Catenin beta 1. (744 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (349 aa)
STAT3Signal transducer and activator of transcription. (771 aa)
PPP2R2CSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa)
ENSVURP00010029419Tyrosine-protein kinase. (1180 aa)
ENSVURP00010029447Tyrosine-protein kinase. (1149 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (294 aa)
IRF9Interferon regulatory factor 9. (411 aa)
ENSVURP00010029953Uncharacterized protein; Belongs to the peptidase C14A family. (274 aa)
LOC114040557Uncharacterized protein; Belongs to the peptidase C14A family. (276 aa)
CDK4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (338 aa)
E2F2E2F transcription factor 2. (431 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
CLDN16Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (235 aa)
EIF2S1S1 motif domain-containing protein. (315 aa)
RB1Uncharacterized protein. (927 aa)
STAT2Signal transducer and activator of transcription. (806 aa)
CDK2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (346 aa)
CLDN10Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (231 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (191 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1251 aa)
PIK3CDUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1075 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (164 aa)
TBK1Protein kinase domain-containing protein. (729 aa)
PPARAUncharacterized protein. (468 aa)
LOC114038574Uncharacterized protein. (548 aa)
ENSVURP00010031982Uncharacterized protein. (335 aa)
FADDUncharacterized protein. (193 aa)
ENSVURP00010032211Serine/threonine-protein phosphatase. (309 aa)
CCND1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (292 aa)
TICAM1TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (702 aa)
Your Current Organism:
Vombatus ursinus
NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat
Server load: low (20%) [HD]