STRINGSTRING
ENSVURP00010031295 ENSVURP00010031295 ENSVURP00010003212 ENSVURP00010003212 ENSVURP00010003223 ENSVURP00010003223 TP53 TP53 LEF1 LEF1 HRAS HRAS GADD45G GADD45G RXRA RXRA TCF7 TCF7 MAPK3 MAPK3 CSDE1 CSDE1 NRAS NRAS DDB2 DDB2 LOC114030664 LOC114030664 TPR TPR TCF7L1 TCF7L1 TFG TFG BAX BAX PPARG PPARG GADD45A GADD45A ENSVURP00010017759 ENSVURP00010017759 NTRK1 NTRK1 BRAF BRAF RET RET RXRB RXRB ENSVURP00010019760 ENSVURP00010019760 ENSVURP00010019784 ENSVURP00010019784 KRAS KRAS BAK1 BAK1 NCOA4 NCOA4 GADD45B GADD45B POLK POLK TPM3 TPM3 MAP2K1 MAP2K1 CDKN1A CDKN1A PAX8 PAX8 CTNNB1 CTNNB1 MAPK1 MAPK1 ENSVURP00010031297 ENSVURP00010031297 CCND1 CCND1 ENSVURP00010032288 ENSVURP00010032288 ENSVURP00010032290 ENSVURP00010032290 MAP2K2 MAP2K2 TCF7L2 TCF7L2 CCDC6 CCDC6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSVURP00010031295Uncharacterized protein. (75 aa)
ENSVURP00010003212Uncharacterized protein. (340 aa)
ENSVURP00010003223Nuc_recep-AF1 domain-containing protein. (117 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (370 aa)
LEF1HMG box domain-containing protein. (417 aa)
HRASUncharacterized protein. (189 aa)
GADD45GRibosomal_L7Ae domain-containing protein. (159 aa)
RXRAUncharacterized protein. (483 aa)
TCF7HMG box domain-containing protein. (430 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
CSDE1Uncharacterized protein. (847 aa)
NRASUncharacterized protein. (189 aa)
DDB2Damage specific DNA binding protein 2. (454 aa)
LOC114030664Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (448 aa)
TPRTranslocated promoter region, nuclear basket protein. (2318 aa)
TCF7L1Transcription factor 7 like 1. (597 aa)
TFGPB1 domain-containing protein. (396 aa)
BAXUncharacterized protein. (200 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (539 aa)
GADD45ARibosomal_L7Ae domain-containing protein. (166 aa)
ENSVURP00010017759annotation not available (448 aa)
NTRK1Tyrosine-protein kinase receptor. (743 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (741 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1105 aa)
RXRBRetinoid X receptor beta. (472 aa)
ENSVURP00010019760Uncharacterized protein. (152 aa)
ENSVURP00010019784Uncharacterized protein. (218 aa)
KRASUncharacterized protein. (189 aa)
BAK1Uncharacterized protein. (204 aa)
NCOA4Uncharacterized protein. (619 aa)
GADD45BRibosomal_L7Ae domain-containing protein. (160 aa)
POLKUmuC domain-containing protein. (865 aa)
TPM3Uncharacterized protein; Belongs to the tropomyosin family. (285 aa)
MAP2K1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (393 aa)
CDKN1AUncharacterized protein. (164 aa)
PAX8Paired box 8. (451 aa)
CTNNB1Catenin beta 1. (744 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (349 aa)
ENSVURP00010031297annotation not available (75 aa)
CCND1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (292 aa)
ENSVURP00010032288annotation not available (75 aa)
ENSVURP00010032290annotation not available (75 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
TCF7L2HMG box domain-containing protein. (605 aa)
CCDC6Coiled-coil domain containing 6. (463 aa)
Your Current Organism:
Vombatus ursinus
NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat
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