STRINGSTRING
EDN1 EDN1 LOC114035332 LOC114035332 LOC114035345 LOC114035345 LOC114039876 LOC114039876 MAP2K7 MAP2K7 ENSVURP00010032356 ENSVURP00010032356 LOC114038853 LOC114038853 PIAS4 PIAS4 IFNG IFNG PIK3CD PIK3CD ENSVURP00010031279 ENSVURP00010031279 SDC1 SDC1 PRKCZ PRKCZ CALML6 CALML6 ENSVURP00010029937 ENSVURP00010029937 NPPC NPPC MAPK10 MAPK10 ENSVURP00010028522 ENSVURP00010028522 CTNNB1 CTNNB1 ENSVURP00010028392 ENSVURP00010028392 ENSVURP00010028376 ENSVURP00010028376 ENSVURP00010028310 ENSVURP00010028310 IL1R1 IL1R1 NFKB1 NFKB1 CYBA CYBA NQO1 NQO1 AKT2 AKT2 CAV1 CAV1 CAV2 CAV2 MMP2 MMP2 ENSVURP00010025906 ENSVURP00010025906 MAPK9 MAPK9 SQSTM1 SQSTM1 PIK3R1 PIK3R1 ENSVURP00010025478 ENSVURP00010025478 MAPK13 MAPK13 MAPK14 MAPK14 NFE2L2 NFE2L2 IKBKG IKBKG ENSVURP00010024793 ENSVURP00010024793 ENSVURP00010024679 ENSVURP00010024679 ENSVURP00010024670 ENSVURP00010024670 ENSVURP00010024661 ENSVURP00010024661 ENSVURP00010024482 ENSVURP00010024482 ENSVURP00010024477 ENSVURP00010024477 ENSVURP00010024452 ENSVURP00010024452 TNFRSF1A TNFRSF1A ENSVURP00010023958 ENSVURP00010023958 ACTB ACTB RHOA RHOA ENSVURP00010023750 ENSVURP00010023750 ENSVURP00010023731 ENSVURP00010023731 FOS FOS ITGAV ITGAV ENSVURP00010023342 ENSVURP00010023342 CALML4 CALML4 MEF2C MEF2C RAC1 RAC1 MAP2K5 MAP2K5 LOC114051918 LOC114051918 LOC114024909 LOC114024909 ENSVURP00010022479 ENSVURP00010022479 MGST1 MGST1 ENSVURP00010022183 ENSVURP00010022183 MMP9 MMP9 ENSVURP00010021078 ENSVURP00010021078 BMPR1A BMPR1A MAPK8 MAPK8 MAP2K4 MAP2K4 LOC114049642-2 LOC114049642-2 LOC114045927 LOC114045927 PECAM1 PECAM1 CHUK CHUK CALM1-3 CALM1-3 ENSVURP00010019798 ENSVURP00010019798 ENSVURP00010019792 ENSVURP00010019792 PIK3R2 PIK3R2 ARHGEF2 ARHGEF2 ENSVURP00010019032 ENSVURP00010019032 ENSVURP00010019014 ENSVURP00010019014 ENSVURP00010018782 ENSVURP00010018782 ENSVURP00010018546 ENSVURP00010018546 ENSVURP00010018401 ENSVURP00010018401 ACVR2B ACVR2B CALM1 CALM1 SRC SRC GSTM3 GSTM3 BCL2 BCL2 ASS1 ASS1 PIK3CA PIK3CA ENSVURP00010016302 ENSVURP00010016302 LOC114037805 LOC114037805 MAP2K6 MAP2K6 SUMO2 SUMO2 LOC114043334 LOC114043334 LOC114040352 LOC114040352 LOC114040349 LOC114040349 NOX1 NOX1 KLF2 KLF2 KDR KDR ENSVURP00010013304 ENSVURP00010013304 NCF2 NCF2 ENSVURP00010012954 ENSVURP00010012954 MGST2 MGST2 PLAT PLAT LOC114027891 LOC114027891 CAV3 CAV3 ENSVURP00010012149 ENSVURP00010012149 PVALEF PVALEF LOC114036481 LOC114036481 LOC114036452 LOC114036452 ENSVURP00010012091 ENSVURP00010012091 LOC114036383 LOC114036383 LOC114043289 LOC114043289 CALML3 CALML3 IKBKB IKBKB ACTG1 ACTG1 LOC114052255 LOC114052255 LOC114052254 LOC114052254 MEF2A MEF2A PIK3CB PIK3CB IL1B IL1B ITGA2B ITGA2B LOC114031332 LOC114031332 TXNDC8 TXNDC8 TXN TXN LOC114035871 LOC114035871 JUN JUN LOC114049642 LOC114049642 PRKAA2 PRKAA2 TRPV4 TRPV4 NOS3 NOS3 MAP3K7 MAP3K7 SUMO1 SUMO1 SDC2 SDC2 ENSVURP00010008190 ENSVURP00010008190 MAPK7 MAPK7 BMPR2 BMPR2 CALM1-2 CALM1-2 HSP90B1 HSP90B1 THBD THBD AKT1 AKT1 ACVR2A ACVR2A VEGFA VEGFA HSP90AB1 HSP90AB1 HMOX1 HMOX1 NCF1 NCF1 TXN2 TXN2 HSP90AA1 HSP90AA1 RAC2 RAC2 ENSVURP00010004556 ENSVURP00010004556 ENSVURP00010004518 ENSVURP00010004518 MAP3K5 MAP3K5 TP53 TP53 ENSVURP00010003961 ENSVURP00010003961 PDGFB PDGFB GPC1 GPC1 ENSVURP00010003580 ENSVURP00010003580 ENSVURP00010003565 ENSVURP00010003565 ENSVURP00010003385 ENSVURP00010003385 MGST3 MGST3 BMPR1B BMPR1B SDC4 SDC4 TNF TNF MAPK11 MAPK11 MAPK12 MAPK12 PRKAA1 PRKAA1 RELA RELA VCAM1 VCAM1 DUSP1 DUSP1 ENSVURP00010001026 ENSVURP00010001026 ENSVURP00010000685 ENSVURP00010000685
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EDN1Uncharacterized protein. (214 aa)
LOC114035332Uncharacterized protein; Belongs to the GST superfamily. (241 aa)
LOC114035345Uncharacterized protein; Belongs to the GST superfamily. (242 aa)
LOC114039876Uncharacterized protein. (546 aa)
MAP2K7Protein kinase domain-containing protein. (462 aa)
ENSVURP00010032356Uncharacterized protein; Belongs to the GST superfamily. (239 aa)
LOC114038853Uncharacterized protein; Belongs to the GST superfamily. (267 aa)
PIAS4Protein inhibitor of activated STAT 4. (535 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (164 aa)
PIK3CDUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1075 aa)
ENSVURP00010031279Uncharacterized protein. (392 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (304 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
CALML6Calmodulin like 6. (155 aa)
ENSVURP00010029937Small ubiquitin-related modifier. (95 aa)
NPPCNatriuretic peptide C. (125 aa)
MAPK10Mitogen-activated protein kinase. (449 aa)
ENSVURP00010028522annotation not available (511 aa)
CTNNB1Catenin beta 1. (744 aa)
ENSVURP00010028392annotation not available (94 aa)
ENSVURP00010028376annotation not available (145 aa)
ENSVURP00010028310annotation not available (195 aa)
IL1R1Uncharacterized protein. (561 aa)
NFKB1Uncharacterized protein. (1007 aa)
CYBACytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (191 aa)
NQO1Flavodoxin_2 domain-containing protein. (274 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
MMP2Uncharacterized protein. (664 aa)
ENSVURP00010025906annotation not available (211 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
SQSTM1Uncharacterized protein. (445 aa)
PIK3R1Uncharacterized protein. (725 aa)
ENSVURP00010025478annotation not available (211 aa)
MAPK13Mitogen-activated protein kinase. (356 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
NFE2L2BZIP domain-containing protein. (597 aa)
IKBKGCCHC NOA-type domain-containing protein. (575 aa)
ENSVURP00010024793Ubiquitin-like domain-containing protein. (205 aa)
ENSVURP00010024679Focal_AT domain-containing protein. (115 aa)
ENSVURP00010024670Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (455 aa)
ENSVURP00010024661FERM domain-containing protein. (121 aa)
ENSVURP00010024482annotation not available (87 aa)
ENSVURP00010024477Thioredoxin domain-containing protein. (87 aa)
ENSVURP00010024452annotation not available (224 aa)
TNFRSF1AUncharacterized protein. (459 aa)
ENSVURP00010023958annotation not available (114 aa)
ACTBUncharacterized protein. (375 aa)
RHOAUncharacterized protein. (193 aa)
ENSVURP00010023750Small ubiquitin-related modifier. (92 aa)
ENSVURP00010023731Ubiquitin-like domain-containing protein. (52 aa)
FOSBZIP domain-containing protein. (378 aa)
ITGAVIntegrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1063 aa)
ENSVURP00010023342Thioredoxin domain-containing protein. (145 aa)
CALML4Uncharacterized protein. (153 aa)
MEF2CMADS-box domain-containing protein. (483 aa)
RAC1Uncharacterized protein. (211 aa)
MAP2K5Uncharacterized protein; Belongs to the protein kinase superfamily. (448 aa)
LOC114051918PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (211 aa)
LOC114024909Uncharacterized protein. (464 aa)
ENSVURP00010022479Uncharacterized protein. (114 aa)
MGST1Microsomal glutathione S-transferase 1. (178 aa)
ENSVURP00010022183Uncharacterized protein. (271 aa)
MMP9Uncharacterized protein. (702 aa)
ENSVURP00010021078annotation not available (192 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
MAP2K4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (402 aa)
LOC114049642-2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LOC114045927Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (511 aa)
PECAM1Uncharacterized protein. (729 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (730 aa)
CALM1-3Uncharacterized protein; Belongs to the calmodulin family. (149 aa)
ENSVURP00010019798annotation not available (145 aa)
ENSVURP00010019792Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (299 aa)
PIK3R2Uncharacterized protein. (738 aa)
ARHGEF2Uncharacterized protein. (1230 aa)
ENSVURP00010019032Uncharacterized protein; Belongs to the GST superfamily. (245 aa)
ENSVURP00010019014Uncharacterized protein; Belongs to the calmodulin family. (136 aa)
ENSVURP00010018782Uncharacterized protein; Belongs to the GST superfamily. (244 aa)
ENSVURP00010018546Glutathione S-transferase. (237 aa)
ENSVURP00010018401Uncharacterized protein. (335 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (511 aa)
CALM1Uncharacterized protein; Belongs to the calmodulin family. (150 aa)
SRCTyrosine-protein kinase. (532 aa)
GSTM3Uncharacterized protein. (220 aa)
BCL2BCL2 apoptosis regulator. (256 aa)
ASS1Uncharacterized protein. (438 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ENSVURP00010016302annotation not available (95 aa)
LOC114037805Small ubiquitin-related modifier. (95 aa)
MAP2K6Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (334 aa)
SUMO2Small ubiquitin-related modifier. (95 aa)
LOC114043334C-C motif chemokine. (145 aa)
LOC114040352BTB domain-containing protein. (623 aa)
LOC114040349BTB domain-containing protein. (592 aa)
NOX1NADPH oxidase 1. (587 aa)
KLF2Uncharacterized protein. (392 aa)
KDRUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1349 aa)
ENSVURP00010013304annotation not available (790 aa)
NCF2Uncharacterized protein. (526 aa)
ENSVURP00010012954Uncharacterized protein. (110 aa)
MGST2Microsomal glutathione S-transferase 2. (137 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (564 aa)
LOC114027891Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (790 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (150 aa)
ENSVURP00010012149Integrin beta; Belongs to the integrin beta chain family. (761 aa)
PVALEFParvalbumin like EF-hand containing. (123 aa)
LOC114036481Glutathione S-transferase. (230 aa)
LOC114036452Uncharacterized protein. (222 aa)
ENSVURP00010012091Uncharacterized protein; Belongs to the GST superfamily. (306 aa)
LOC114036383Uncharacterized protein; Belongs to the GST superfamily. (427 aa)
LOC114043289Uncharacterized protein; Belongs to the calmodulin family. (149 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (184 aa)
IKBKBProtein kinase domain-containing protein. (757 aa)
ACTG1Uncharacterized protein. (375 aa)
LOC114052255Uncharacterized protein; Belongs to the peptidase C1 family. (335 aa)
LOC114052254Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (139 aa)
MEF2AMADS-box domain-containing protein. (488 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1052 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (299 aa)
ITGA2BIntegrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1053 aa)
LOC114031332Uncharacterized protein. (192 aa)
TXNDC8Thioredoxin; Belongs to the thioredoxin family. (104 aa)
TXNThioredoxin domain-containing protein. (251 aa)
LOC114035871Uncharacterized protein; Belongs to the peptidase C1 family. (224 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (321 aa)
LOC114049642Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PRKAA2Non-specific serine/threonine protein kinase. (551 aa)
TRPV4ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1193 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (607 aa)
SUMO1Small ubiquitin-related modifier. (101 aa)
SDC2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa)
ENSVURP00010008190TPR_REGION domain-containing protein. (257 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (807 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1040 aa)
CALM1-2Uncharacterized protein; Belongs to the calmodulin family. (195 aa)
HSP90B1HATPase_c domain-containing protein. (800 aa)
THBDThrombomodulin. (567 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (400 aa)
HSP90AB1HATPase_c domain-containing protein. (723 aa)
HMOX1Uncharacterized protein. (290 aa)
NCF1Uncharacterized protein. (390 aa)
TXN2Thioredoxin domain-containing protein. (165 aa)
HSP90AA1HATPase_c domain-containing protein. (728 aa)
RAC2Uncharacterized protein. (306 aa)
ENSVURP00010004556Small ubiquitin-related modifier. (94 aa)
ENSVURP00010004518Small ubiquitin-related modifier. (86 aa)
MAP3K5Protein kinase domain-containing protein. (1387 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (370 aa)
ENSVURP00010003961Uncharacterized protein. (109 aa)
PDGFBPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (239 aa)
GPC1Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (556 aa)
ENSVURP00010003580EF-hand domain-containing protein; Belongs to the calmodulin family. (73 aa)
ENSVURP00010003565Uncharacterized protein. (123 aa)
ENSVURP00010003385Uncharacterized protein. (125 aa)
MGST3Microsomal glutathione S-transferase 3. (154 aa)
BMPR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (534 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (197 aa)
TNFTNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (232 aa)
MAPK11Mitogen-activated protein kinase. (362 aa)
MAPK12Mitogen-activated protein kinase. (365 aa)
PRKAA1Non-specific serine/threonine protein kinase. (559 aa)
RELARHD domain-containing protein. (538 aa)
VCAM1Uncharacterized protein. (739 aa)
DUSP1Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (339 aa)
ENSVURP00010001026Uncharacterized protein. (71 aa)
ENSVURP00010000685Uncharacterized protein. (224 aa)
Your Current Organism:
Vombatus ursinus
NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat
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