STRINGSTRING
ABF65618.1 ABF65618.1 rbsK rbsK coaE coaE ABF65575.1 ABF65575.1 regB regB ABF65543.1 ABF65543.1 ABF65522.1 ABF65522.1 ABF65510.1 ABF65510.1 pleC pleC gpmI gpmI ABF65485.1 ABF65485.1 ABF65478.1 ABF65478.1 Transketolase Transketolase ABF65466.1 ABF65466.1 ABF65456.1 ABF65456.1 lpxK lpxK ABF65342.1 ABF65342.1 ABF65299.1 ABF65299.1 ABF65248.1 ABF65248.1 ABF65184.1 ABF65184.1 ABF65172.1 ABF65172.1 ABF65171.1 ABF65171.1 ABF65169.1 ABF65169.1 ABF65145.1 ABF65145.1 ABF65041.1 ABF65041.1 ABF65022.1 ABF65022.1 ABF64961.1 ABF64961.1 cheR5 cheR5 ABF64915.1 ABF64915.1 ABF64888.1 ABF64888.1 prs prs ABF64803.1 ABF64803.1 ABF64742.1 ABF64742.1 ABF64729.1 ABF64729.1 ABF64708.1 ABF64708.1 ABF64698.1 ABF64698.1 ABF64683.1 ABF64683.1 ABF64667.1 ABF64667.1 ABF64666.1 ABF64666.1 ABF64587.1 ABF64587.1 ABF64548.1 ABF64548.1 nadK nadK ABF64294.1 ABF64294.1 ABF64240.1 ABF64240.1 adk-2 adk-2 ABF64212.1 ABF64212.1 ABF64195.1 ABF64195.1 ABF64183.1 ABF64183.1 aroK aroK pyrH pyrH ABF64114.1 ABF64114.1 ABF64095.1 ABF64095.1 ABF64093.1 ABF64093.1 ABF64071.1 ABF64071.1 gmk gmk ABF63996.1 ABF63996.1 cckA cckA ABF63949.1 ABF63949.1 ABF63939.1 ABF63939.1 proB proB ABF63927.1 ABF63927.1 ABF63926.1 ABF63926.1 pgk pgk pdhA pdhA ABF63811.1 ABF63811.1 ABF63764.1 ABF63764.1 cheR4 cheR4 hik-2 hik-2 ndk ndk eno eno anmK anmK ABF63610.1 ABF63610.1 ABF63589.1 ABF63589.1 aphA aphA tpiA tpiA coaX coaX ABF63403.1 ABF63403.1 tdk tdk cysC cysC ABF63287.1 ABF63287.1 ABF63273.1 ABF63273.1 cheR3 cheR3 ABF63188.1 ABF63188.1 ABF63187.1 ABF63187.1 ABF63139.1 ABF63139.1 pgi pgi ABF63104.1 ABF63104.1 ABF63096.1 ABF63096.1 ABF63094.1 ABF63094.1 arcB arcB ABF63049.1 ABF63049.1 ABF63041.1 ABF63041.1 argB argB adk adk hik hik cmk cmk ABF62872.1 ABF62872.1 ABF62871.1 ABF62871.1 ABF62845.1 ABF62845.1 ABF62800.1 ABF62800.1 ABF62798.1 ABF62798.1 ABF62789.1 ABF62789.1 xylB xylB ABF65759.1 ABF65759.1 ABF65758.1 ABF65758.1 ABF65711.1 ABF65711.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABF65618.1Hpt protein. (118 aa)
rbsKPfkB; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (290 aa)
coaEDephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (197 aa)
ABF65575.1Aminoglycoside phosphotransferase. (332 aa)
regBTwo component sensor kinase. (465 aa)
ABF65543.1Hypothetical protein. (173 aa)
ABF65522.1Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (367 aa)
ABF65510.1Branched-chain alpha-keto acid dehydrogenase E1 component. (413 aa)
pleCHistidine kinase. (761 aa)
gpmIPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (506 aa)
ABF65485.1PfkB. (308 aa)
ABF65478.1Multi-sensor hybrid histidine kinase. (1096 aa)
TransketolaseTransketolase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (794 aa)
ABF65466.1Periplasmic sensor signal transduction histidine kinase. (461 aa)
ABF65456.1Signal transduction histidine kinase. (613 aa)
lpxKlipid-A-disaccharide synthase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (333 aa)
ABF65342.1Hypothetical protein. (336 aa)
ABF65299.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (189 aa)
ABF65248.1Pyruvate kinase; Belongs to the pyruvate kinase family. (481 aa)
ABF65184.1PfkB. (330 aa)
ABF65172.1Periplasmic sensor signal transduction histidine kinase. (577 aa)
ABF65171.1Hpr(Ser) kinase/phosphatase. (162 aa)
ABF65169.1PTS system fructose subfamily IIA component. (134 aa)
ABF65145.1Hypothetical protein. (268 aa)
ABF65041.1Pyruvate phosphate dikinase. (854 aa)
ABF65022.1Histidine triad (HIT) protein. (139 aa)
ABF64961.1Diguanylate cyclase/phosphodiesterase. (582 aa)
cheR5MCP methyltransferase, CheR-type. (824 aa)
ABF64915.1Hypothetical protein. (68 aa)
ABF64888.1Diguanylate cyclase/phosphodiesterase. (904 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (340 aa)
ABF64803.1FMN adenylyltransferase / riboflavin kinase; Belongs to the ribF family. (310 aa)
ABF64742.1Histidine kinase. (354 aa)
ABF64729.1Periplasmic sensor signal transduction histidine kinase. (592 aa)
ABF64708.1Fructose-bisphosphate aldolase. (300 aa)
ABF64698.1Thiamine pyrophosphokinase. (223 aa)
ABF64683.1Transcriptional regulator, Crp/Fnr family. (222 aa)
ABF64667.1Aspartate kinase; Belongs to the aspartokinase family. (412 aa)
ABF64666.1PTSINtr with GAF domain, PtsP; Belongs to the PEP-utilizing enzyme family. (746 aa)
ABF64587.1GAF sensor hybrid histidine kinase. (579 aa)
ABF64548.1Periplasmic sensor signal transduction histidine kinase. (583 aa)
nadKNAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (251 aa)
ABF64294.1Acetyl-CoA C-acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)
ABF64240.1Periplasmic sensor signal transduction histidine kinase. (896 aa)
adk-2Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (227 aa)
ABF64212.1Periplasmic sensor signal transduction histidine kinase. (442 aa)
ABF64195.1Periplasmic sensor signal transduction histidine kinase. (600 aa)
ABF64183.1Protein of unknown function DUF1321. (159 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (196 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (249 aa)
ABF64114.1Protein of unknown function DUF344. (289 aa)
ABF64095.1Signal transduction histidine kinase, nitrogen specific, NtrB. (362 aa)
ABF64093.1Multi-sensor signal transduction histidine kinase. (759 aa)
ABF64071.1PfkB. (302 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (217 aa)
ABF63996.1Histidine kinase. (346 aa)
cckAMulti-sensor hybrid histidine kinase. (769 aa)
ABF63949.1Multi-sensor signal transduction histidine kinase. (769 aa)
ABF63939.1Hypothetical protein. (198 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (368 aa)
ABF63927.1Carbohydrate kinase FGGY; Belongs to the FGGY kinase family. (503 aa)
ABF63926.1Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase. (278 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (396 aa)
pdhAPyruvate dehydrogenase (lipoamide); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (337 aa)
ABF63811.1Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (458 aa)
ABF63764.1Response regulator receiver protein. (131 aa)
cheR4Signal transduction histidine kinase with CheB and CheR activity. (1248 aa)
hik-2PAS/PAC sensor hybrid histidine kinase. (823 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (425 aa)
anmKProtein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (375 aa)
ABF63610.1Periplasmic sensor signal transduction histidine kinase. (474 aa)
ABF63589.1Phosphoglycerate mutase. (191 aa)
aphAPAS/PAC sensor signal transduction histidine kinase. (394 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (246 aa)
coaXPantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (260 aa)
ABF63403.1LAO/AO transport system ATPase. (333 aa)
tdkThymidine kinase. (200 aa)
cysCAdenylylsulfate kinase / sulfate adenylyltransferase; Catalyzes the synthesis of activated sulfate. (572 aa)
ABF63287.1Aspartate kinase. (478 aa)
ABF63273.1Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. (193 aa)
cheR3MCP methyltransferase, CheR-type. (837 aa)
ABF63188.1Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (206 aa)
ABF63187.1Phosphoglycerate mutase. (193 aa)
ABF63139.1Periplasmic sensor signal transduction histidine kinase. (658 aa)
pgiGlucose-6-phosphate isomerase. (536 aa)
ABF63104.1Fructokinase. (207 aa)
ABF63096.1Glucokinase; Belongs to the bacterial glucokinase family. (320 aa)
ABF63094.1Acetyl-CoA C-acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
arcBMulti-sensor hybrid histidine kinase. (827 aa)
ABF63049.1Periplasmic sensor signal transduction histidine kinase. (461 aa)
ABF63041.1Diguanylate cyclase/phosphodiesterase. (499 aa)
argBN-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (286 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (193 aa)
hikHistidine kinase. (476 aa)
cmkCytidylate kinase. (203 aa)
ABF62872.1Putative anti-sigma regulatory factor serine/threonine protein kinase. (140 aa)
ABF62871.1Hypothetical protein. (214 aa)
ABF62845.1PAS/PAC sensor hybrid histidine kinase. (634 aa)
ABF62800.1Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
ABF62798.1Putative anti-sigma regulatory factor serine/threonine protein kinase. (146 aa)
ABF62789.1Protein of unknown function DUF343; Belongs to the UPF0434 family. (61 aa)
xylBXylulokinase. (483 aa)
ABF65759.12-octaprenylphenol hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily. (508 aa)
ABF65758.1Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
ABF65711.1Aminoglycoside phosphotransferase. (282 aa)
Your Current Organism:
Ruegeria sp. TM1040
NCBI taxonomy Id: 292414
Other names: R. sp. TM1040, Silicibacter sp. TM1040
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