STRINGSTRING
Tbd_0570 Tbd_0570 Tbd_0572 Tbd_0572 ppc ppc Tbd_0640 Tbd_0640 Tbd_1970 Tbd_1970 Tbd_1998 Tbd_1998 Tbd_2119 Tbd_2119 Tbd_2174 Tbd_2174 Tbd_2282 Tbd_2282 Tbd_2350 Tbd_2350 Tbd_2474 Tbd_2474 Tbd_2475 Tbd_2475 Tbd_2655 Tbd_2655 Tbd_2758 Tbd_2758 Tbd_0823 Tbd_0823 sucD sucD sucC sucC Tbd_0643 Tbd_0643 nuoM nuoM nuoL nuoL nuoK nuoK nuoI nuoI nuoH nuoH nuoG nuoG nuoE nuoE Tbd_1107 Tbd_1107 Tbd_1029 Tbd_1029 Tbd_0891 Tbd_0891 Tbd_0872 Tbd_0872 Tbd_0854 Tbd_0854 Tbd_0139 Tbd_0139 Tbd_0137 Tbd_0137 nuoN nuoN Tbd_1182 Tbd_1182 Tbd_1183 Tbd_1183 Tbd_1184 Tbd_1184 Tbd_1185 Tbd_1185 Tbd_1187 Tbd_1187 Tbd_1188 Tbd_1188 Tbd_1189 Tbd_1189 Tbd_1263 Tbd_1263 Tbd_1375 Tbd_1375 Tbd_1378 Tbd_1378 Tbd_1404 Tbd_1404 Tbd_1648 Tbd_1648 Tbd_1739 Tbd_1739 Tbd_1740 Tbd_1740 Tbd_1741 Tbd_1741 Tbd_1755 Tbd_1755 Tbd_1832 Tbd_1832 Tbd_0047 Tbd_0047 ubiE ubiE Tbd_0326 Tbd_0326 Tbd_0330 Tbd_0330 Tbd_0338 Tbd_0338 Tbd_0341 Tbd_0341 Tbd_0495 Tbd_0495 Tbd_0560 Tbd_0560 Tbd_0561 Tbd_0561 Tbd_0571 Tbd_0571
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Tbd_0570DMSO reductase chain A; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (958 aa)
Tbd_0572DMSO reductase chain C. (312 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (939 aa)
Tbd_0640Cytochrome c oxidase cbb3-type, subunit III; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex. (317 aa)
Tbd_1970Putative denitrification protein NorE. (201 aa)
Tbd_1998Oxidoreductase, FAD-binding. (460 aa)
Tbd_2119Aspartate ammonia-lyase. (466 aa)
Tbd_2174Putative membrane protein. (426 aa)
Tbd_2282Adenylylsulfate reductase, alpha subunit. (622 aa)
Tbd_2350Conserved hypothetical protein. (280 aa)
Tbd_2474Molybdopterin oxidoreductase, membrane subunit. (400 aa)
Tbd_2475Iron-sulfur cluster protein. (259 aa)
Tbd_2655NADH dehydrogenase. (559 aa)
Tbd_2758Methyltransferase. (256 aa)
Tbd_0823Nitric-oxide reductase subunit B. (456 aa)
sucDsuccinyl-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (297 aa)
sucCsuccinyl-CoA synthase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (386 aa)
Tbd_0643Cytochrome c oxidase cbb3-type, subunit I; Belongs to the heme-copper respiratory oxidase family. (473 aa)
nuoMNADH dehydrogenase I chain M. (494 aa)
nuoLNADH dehydrogenase I chain L. (669 aa)
nuoKNADH dehydrogenase I chain K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (101 aa)
nuoINADH-quinone oxidoreductase chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (162 aa)
nuoHNADH dehydrogenase I chain H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. (343 aa)
nuoGNADH-quinone oxidoreductase, chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (784 aa)
nuoENADH dehydrogenase I chain E. (168 aa)
Tbd_1107Putative ferredoxin. (442 aa)
Tbd_1029Probable cytochrome b561. (181 aa)
Tbd_0891Aconitate hydratase 1. (939 aa)
Tbd_0872Adenylylsulfate reductase, alpha subunit. (673 aa)
Tbd_0854Isocitrate dehydrogenase (NADP). (413 aa)
Tbd_0139Cytochrome b, putative. (218 aa)
Tbd_0137Diheme cytochrome c. (177 aa)
nuoNNADH dehydrogenase I chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (483 aa)
Tbd_1182Succinate dehydrogenase cytochrome b-556 subunit. (126 aa)
Tbd_1183Succinate dehydrogenase, cytochrome b subunit. (119 aa)
Tbd_1184Succinate dehydrogenase; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (584 aa)
Tbd_1185Succinate dehydrogenase; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (231 aa)
Tbd_1187Citrate synthase I; Belongs to the citrate synthase family. (431 aa)
Tbd_11882-oxoglutarate dehydrogenase, E1 component. (897 aa)
Tbd_1189Dihydrolipoamide succinyltransferase. (379 aa)
Tbd_1263Conserved hypothetical protein. (433 aa)
Tbd_1375Ni-Fe hydrogenase large chain; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (596 aa)
Tbd_1378Ni-Fe hydrogenase, small subunit. (360 aa)
Tbd_1404Nitrate reductase, beta subunit. (522 aa)
Tbd_1648Heterodisulfide reductase, subunit A. (427 aa)
Tbd_1739Putative tetrathionate reductase subunit B. (245 aa)
Tbd_1740Putative tetrathionate reductase subunit C. (361 aa)
Tbd_1741Putative tetrathionate reductase, subunit A; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1038 aa)
Tbd_1755Conserved hypothetical protein. (144 aa)
Tbd_1832Cytochrome B subunit of cytochrome bc1; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (410 aa)
Tbd_0047Glycolate oxidase, subunit GlcD. (483 aa)
ubiEUbiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (244 aa)
Tbd_0326Cytochrome c oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (526 aa)
Tbd_0330Cytochrome c oxidase, subunit III. (288 aa)
Tbd_0338Cytochrome c oxidase cbb3-type, subunit I; Belongs to the heme-copper respiratory oxidase family. (484 aa)
Tbd_0341Cytochrome c oxidase cbb3-type, subunit III; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex. (306 aa)
Tbd_0495NADH dehydrogenase (quinone). (504 aa)
Tbd_0560Putative additional subunit of nitric oxide reductase (Nor) complex, membrane protein. (197 aa)
Tbd_0561Nitric-oxide reductase subunit B; Belongs to the heme-copper respiratory oxidase family. (467 aa)
Tbd_0571DMSO reductase chain B. (231 aa)
Your Current Organism:
Thiobacillus denitrificans ATCC 25259
NCBI taxonomy Id: 292415
Other names: T. denitrificans ATCC 25259, Thiobacillus denitrificans str. ATCC 25259, Thiobacillus denitrificans strain ATCC 25259
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.