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STH3153 STH3153 STH3167 STH3167 STH3174 STH3174 STH3176 STH3176 STH3217 STH3217 STH2751 STH2751 STH2752 STH2752 nuoM2 nuoM2 nuoK2 nuoK2 nuoI2 nuoI2 nuoD2 nuoD2 nuoC2 nuoC2 nuoB2 nuoB2 STH2841 STH2841 STH2945 STH2945 ecfA2 ecfA2 ecfA1 ecfA1 STH3103 STH3103 STH3147 STH3147 STH998 STH998 STH934 STH934 atpC atpC atpD atpD atpG atpG atpA atpA atpH atpH STH875 STH875 atpF atpF atpE atpE STH855 STH855 atpB atpB STH83 STH83 STH758 STH758 STH678 STH678 STH653 STH653 STH607 STH607 STH548 STH548 argH-2 argH-2 potA-2 potA-2 STH382 STH382 STH38 STH38 STH3293 STH3293 STH3275 STH3275 STH3218 STH3218 STH1094 STH1094 tatC tatC STH1066 STH1066 STH3186 STH3186 STH3207 STH3207 STH3209 STH3209 STH3211 STH3211 STH1096 STH1096 mutS2 mutS2 potA potA STH1147 STH1147 STH1155 STH1155 STH1156 STH1156 STH1226 STH1226 tatA tatA STH1235 STH1235 STH1283 STH1283 STH1507 STH1507 nuoB1 nuoB1 nuoC1 nuoC1 argH argH nuoD1 nuoD1 nuoE1 nuoE1 nuoF1 nuoF1 nuoI1 nuoI1 nuoK1 nuoK1 STH1652 STH1652 STH1659 STH1659 STH166 STH166 STH1782 STH1782 STH1809 STH1809 STH1879 STH1879 STH1880 STH1880 tatA-2 tatA-2 STH1933 STH1933 STH1971 STH1971 STH2158 STH2158 STH2159 STH2159 STH2171 STH2171 STH2385 STH2385 STH3148 STH3148 STH2516 STH2516 STH2627 STH2627 STH3152 STH3152 STH2632 STH2632 STH2637 STH2637 STH2640 STH2640
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STH3153Cytochrome C oxidase heme b and copper-binding subunit. (467 aa)
STH3167Pyruvate flavodoxin dehydrogenase. (1183 aa)
STH3174Succinate dehydrogenase iron-sulfur protein. (251 aa)
STH3176Succinate dehydrogenase cytochrome b558 subunit. (211 aa)
STH3217ABC transporter ATP-binding protein; Belongs to the ABC transporter superfamily. (348 aa)
STH2751ABC transporter permease protein. (567 aa)
STH2752ABC transporter ATP-binding protein; Belongs to the ABC transporter superfamily. (370 aa)
nuoM2NADH dehydrogenase I subunit M. (508 aa)
nuoK2NADH dehydrogenase I subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (107 aa)
nuoI2NADH dehydrogenase I subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (240 aa)
nuoD2NADH dehydrogenase I subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family. (384 aa)
nuoC2NADH dehydrogenase I subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 30 kDa subunit family. (156 aa)
nuoB2NADH dehydrogenase I subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (182 aa)
STH2841Na+/H+ antiporter; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (622 aa)
STH2945Conserved hypothetical protein. (439 aa)
ecfA2ABC-type cobalt transport system ATPase component; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (288 aa)
ecfA1ABC-type cobalt transport system ATPase component; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (287 aa)
STH3103NADH dehydrogenase subunit. (394 aa)
STH3147Putative menaquinol-cytochrome C reductase. (253 aa)
STH998Molybdenum ABC transporter ATP-binding protein; Belongs to the ABC transporter superfamily. (359 aa)
STH934Ferredoxin. (96 aa)
atpCATP synthase epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (139 aa)
atpDATP synthase beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (472 aa)
atpGATP synthase gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (288 aa)
atpAATP synthase alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (506 aa)
atpHATP synthase delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (186 aa)
STH875ABC transporter permease protein. (253 aa)
atpFATP synthase B subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (162 aa)
atpEATP synthase C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (77 aa)
STH855ABC transporter permease protein. (403 aa)
atpBATP synthase A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (257 aa)
STH83Conserved domain protein. (89 aa)
STH758ABC transporter permease protein. (258 aa)
STH678ABC transporter permease protein. (852 aa)
STH653Iron ABC transporter ATP-binding protein. (257 aa)
STH607Putative ABC transporter permease protein. (367 aa)
STH548ABC transporter ATP-binding protein. (351 aa)
argH-2Argininosuccinate lyase. (461 aa)
potA-2Spermidine/putrescine ABC transporter ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (348 aa)
STH382Tungstate ABC transporter ATP binding protein. (256 aa)
STH38Lysine 5,6-aminomutase beta subunit. (245 aa)
STH3293Iron hydrogenase. (456 aa)
STH3275Putative membrane efflux protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (359 aa)
STH3218ABC transporter permease protein. (556 aa)
STH1094Potassium uptake system protein. (216 aa)
tatCConserved hypothetical protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Belongs to the TatC family. (238 aa)
STH1066UDP-N-acetylmuramyl tripeptide synthase. (464 aa)
STH31862-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (175 aa)
STH3207Putative iron hydrogenase small subunit gamma. (186 aa)
STH3209Iron hydrogenase. (596 aa)
STH3211ABC transporter permease protein. (643 aa)
STH1096Potassium uptake system protein. (221 aa)
mutS2DNA mismatch repair protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (793 aa)
potAABC transporter ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (350 aa)
STH1147ABC transporter permease protein. (559 aa)
STH1155ABC transporter permease protein. (552 aa)
STH1156ABC transporter ATP-binding protein; Belongs to the ABC transporter superfamily. (347 aa)
STH1226Conserved hypothetical protein. (300 aa)
tatAPutative Sec-independent protein translocase; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. Belongs to the TatA/E family. (67 aa)
STH1235Sugar ABC transporter ATP-binding protein. (500 aa)
STH1283Iron-siderophore uptake ABC system ATP-binding component. (562 aa)
STH1507ABC transporter ATP-binding protein. (265 aa)
nuoB1NADH dehydrogenase I subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (153 aa)
nuoC1NADH dehydrogenase I subunit C. (200 aa)
argHArgininosuccinate lyase. (538 aa)
nuoD1NADH dehydrogenase I subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family. (404 aa)
nuoE1NADH dehydrogenase I subunit E. (274 aa)
nuoF1NADH dehydrogenase I subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (425 aa)
nuoI1NADH dehydrogenase I subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (162 aa)
nuoK1NADH dehydrogenase I subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (102 aa)
STH1652ABC transporter permease protein. (255 aa)
STH1659Na+/H+ antiporter subunit. (159 aa)
STH166Conserved domain protein. (194 aa)
STH1782Sugar ABC transportor ATP-binding protein; Belongs to the ABC transporter superfamily. (364 aa)
STH1809Conserved hypothetical protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (529 aa)
STH1879ABC transporter permease protein. (266 aa)
STH1880ABC transporter ATP-binding protein. (250 aa)
tatA-2Putative Sec-independent protein translocase; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. Belongs to the TatA/E family. (71 aa)
STH1933Iron ABC transporter ATP-binding protein. (274 aa)
STH1971ABC transporter permease protein. (249 aa)
STH2158Cobalt ABC transporter ATP-binding protein. (284 aa)
STH2159Cobalt ABC transporter ATP-binding protein. (274 aa)
STH2171Conserved hypothetical protein. (349 aa)
STH2385Conserved hypothetical protein. (367 aa)
STH3148Menaquinol-cytochrome C reductase. (258 aa)
STH2516ABC transporter permease protein. (253 aa)
STH2627Glycine betaine/carnitine/choline ABC transporter substrate-binding protein. (304 aa)
STH3152Cytochrome C oxidase mono-heme subunit. (320 aa)
STH2632ABC transporter permease protein. (681 aa)
STH2637Succinate dehydrogenase membrane subunit. (140 aa)
STH2640Succinate dehydrogenase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (243 aa)
Your Current Organism:
Symbiobacterium thermophilum
NCBI taxonomy Id: 292459
Other names: S. thermophilum IAM 14863, Symbiobacterium thermophilum IAM 14863, Symbiobacterium thermophilum str. IAM 14863, Symbiobacterium thermophilum strain IAM 14863
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