STRINGSTRING
iscS iscS selA selA ANU43044.2 ANU43044.2 ANU39645.1 ANU39645.1 ANU40054.1 ANU40054.1 serC serC ANU40301.1 ANU40301.1 hemL hemL ANU40323.1 ANU40323.1 ANU40546.1 ANU40546.1 ANU40881.1 ANU40881.1 ANU41038.1 ANU41038.1 ANU41223.1 ANU41223.1 ANU42960.2 ANU42960.2 ANU41281.1 ANU41281.1 ANU41367.1 ANU41367.1 glyA glyA ANU41455.1 ANU41455.1 ANU41460.1 ANU41460.1 hisC hisC argD argD ANU41595.1 ANU41595.1 ANU42073.1 ANU42073.1 ANU42094.1 ANU42094.1 ANU42269.1 ANU42269.1 gcvPA gcvPA ANU42298.1 ANU42298.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
iscSCysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. (398 aa)
selAL-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (443 aa)
ANU43044.2Amino acid decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (442 aa)
ANU39645.1Hemolysin; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
ANU40054.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa)
serC3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (361 aa)
ANU40301.1Threonine-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa)
hemLGlutamate-1-semialdehyde-2,1-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)
ANU40323.1Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
ANU40546.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
ANU40881.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (466 aa)
ANU41038.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
ANU41223.1Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
ANU42960.2Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
ANU41281.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (416 aa)
ANU41367.1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (408 aa)
ANU41455.1Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)
ANU41460.1O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. (429 aa)
hisCHistidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (351 aa)
argDAspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (392 aa)
ANU41595.1Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
ANU42073.1Catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
ANU42094.1O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. (427 aa)
ANU42269.1Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
gcvPAGlycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (435 aa)
ANU42298.1Glycine dehydrogenase (aminomethyl-transferring); Acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)
Your Current Organism:
Flavonifractor plautii
NCBI taxonomy Id: 292800
Other names: ATCC 29863, ATCC 49531 [[Clostridium orbiscindens]], Bacillus plauti, CCUG 28093, Clostridium orbiscindens, DSM 4000, DSM 6740 [[Clostridium orbiscindens]], DSM 6749 [[Clostridium orbiscindens]], Eubacterium plautii, F. plautii, Fusobacterium plautii, Fusocillus plauti, Pseudoflavonifractor sp. YL31, Zuberella plauti, strain Prevot S1
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