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| | CD943_12765 | Unannotated protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (364 aa) |
| | ilvE | Unannotated protein; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (247 aa) |
| | cysK | Unannotated protein. (329 aa) |
| | pyk | Unannotated protein; Belongs to the pyruvate kinase family. (487 aa) |
| | CD943_08330 | Unannotated protein. (451 aa) |
| | fbp | Unannotated protein; Belongs to the FBPase class 1 family. (322 aa) |
| | GcvT | Unannotated protein. (370 aa) |
| | gcvH | Unannotated protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (121 aa) |
| | gcvPA | Unannotated protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (448 aa) |
| | CD943_11890 | Unannotated protein. (525 aa) |
| | CD943_11800 | Unannotated protein. (482 aa) |
| | thrB | Unannotated protein; Belongs to the pseudomonas-type ThrB family. (320 aa) |
| | CD943_11785 | Unannotated protein. (578 aa) |
| | metXS | Unannotated protein; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. (369 aa) |
| | metB | Unannotated protein. (392 aa) |
| | CD943_11635 | Unannotated protein. (399 aa) |
| | CD943_11615 | Unannotated protein. (244 aa) |
| | lhyD | Unannotated protein. (445 aa) |
| | CD943_04060 | Unannotated protein; Belongs to the PEP-utilizing enzyme family. (896 aa) |
| | CD943_04015 | Unannotated protein. (164 aa) |
| | CD943_03675 | Unannotated protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (386 aa) |
| | purA | Unannotated protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (431 aa) |
| | CD943_03645 | Unannotated protein; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa) |
| | pgk | Unannotated protein; Belongs to the phosphoglycerate kinase family. (398 aa) |
| | gap | Unannotated protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa) |
| | purT | Unannotated protein; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (397 aa) |
| | tkt | Unannotated protein; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (664 aa) |
| | purL | Unannotated protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the amm [...] (736 aa) |
| | purQ | Unannotated protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the amm [...] (220 aa) |
| | yexA | Unannotated protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the amm [...] (79 aa) |
| | purC | Unannotated protein; Belongs to the SAICAR synthetase family. (252 aa) |
| | CD943_03495 | Unannotated protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (433 aa) |
| | cysS | Unannotated protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (468 aa) |
| | AceA | Unannotated protein. (425 aa) |
| | CD943_03185 | Unannotated protein; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (629 aa) |
| | purK | Unannotated protein; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (357 aa) |
| | purE | Unannotated protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (168 aa) |
| | glcB | Unannotated protein; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (725 aa) |
| | glyA | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (427 aa) |
| | rpiA | Unannotated protein; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (227 aa) |
| | glmU | Unannotated protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (450 aa) |
| | folD | Unannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (307 aa) |
| | CD943_15250 | Unannotated protein. (401 aa) |
| | CD943_15210 | Unannotated protein. (320 aa) |
| | metF | Unannotated protein; Belongs to the methylenetetrahydrofolate reductase family. (315 aa) |
| | CD943_15200 | Unannotated protein. (358 aa) |
| | CD943_15195 | Unannotated protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (888 aa) |
| | metC | Unannotated protein. (397 aa) |
| | pyrB | Unannotated protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (327 aa) |
| | CD943_15085 | Unannotated protein. (432 aa) |
| | tpiA | Unannotated protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (249 aa) |
| | trpE | Unannotated protein; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. (507 aa) |
| | CD943_15015 | Unannotated protein. (196 aa) |
| | trpD | Unannotated protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (344 aa) |
| | trpC | Unannotated protein; Belongs to the TrpC family. (267 aa) |
| | gltA | Unannotated protein; Belongs to the citrate synthase family. (433 aa) |
| | CD943_14470 | Unannotated protein. (477 aa) |
| | CD943_14465 | Unannotated protein. (1508 aa) |
| | guaA | Unannotated protein; Catalyzes the synthesis of GMP from XMP. (520 aa) |
| | CD943_14380 | Unannotated protein. (231 aa) |
| | guaB | Unannotated protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (486 aa) |
| | cysE | Unannotated protein. (273 aa) |
| | CD943_14195 | Unannotated protein. (387 aa) |
| | CD943_14190 | Unannotated protein. (467 aa) |
| | pckG | Unannotated protein; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (614 aa) |
| | CD943_11055 | Unannotated protein. (734 aa) |
| | argB | Unannotated protein; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (352 aa) |
| | CD943_11045 | Unannotated protein. (237 aa) |
| | dapD | Unannotated protein; Belongs to the transferase hexapeptide repeat family. (289 aa) |
| | PutA | Unannotated protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1036 aa) |
| | aroC | Unannotated protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (361 aa) |
| | glnA | Unannotated protein. (469 aa) |
| | dapA | Unannotated protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (294 aa) |
| | eno | Unannotated protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (425 aa) |
| | acoA | Unannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (342 aa) |
| | CD943_16275 | Unannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (449 aa) |
| | CD943_16285 | Unannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (418 aa) |
| | lpdA | Unannotated protein. (468 aa) |
| | CD943_16300 | Unannotated protein. (334 aa) |
| | aroB | Unannotated protein; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (368 aa) |
| | aroK | Unannotated protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (189 aa) |
| | CD943_00885 | Unannotated protein. (338 aa) |
| | SseA | Unannotated protein. (281 aa) |
| | argC | Unannotated protein; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (311 aa) |
| | CD943_01445 | Unannotated protein. (253 aa) |
| | CD943_01450 | Unannotated protein. (188 aa) |
| | CD943_01530 | Unannotated protein. (502 aa) |
| | pyrE | Unannotated protein; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (194 aa) |
| | aroQ | Unannotated protein; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (151 aa) |
| | purM | Unannotated protein. (345 aa) |
| | purN | Unannotated protein; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (194 aa) |
| | purF | Unannotated protein; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (501 aa) |
| | CD943_10045 | Unannotated protein. (352 aa) |
| | argJ | Unannotated protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (460 aa) |
| | CD943_10365 | Unannotated protein; Belongs to the aspartokinase family. (429 aa) |
| | CD943_10490 | Unannotated protein. (400 aa) |
| | prs | Unannotated protein; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (311 aa) |
| | CD943_02445 | Unannotated protein. (423 aa) |
| | leuB | Unannotated protein; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (370 aa) |
| | CD943_02720 | Unannotated protein. (428 aa) |
| | purD | Unannotated protein; Belongs to the GARS family. (425 aa) |
| | CD943_05225 | Unannotated protein; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (345 aa) |
| | aroA | Unannotated protein; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (444 aa) |
| | gabD | Unannotated protein; Belongs to the aldehyde dehydrogenase family. (481 aa) |
| | CD943_05510 | Unannotated protein. (1127 aa) |
| | CD943_05565 | Unannotated protein; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (406 aa) |
| | carA | Unannotated protein; Belongs to the CarA family. (386 aa) |
| | carB | Unannotated protein; Belongs to the CarB family. (1099 aa) |
| | ilvA | Unannotated protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (534 aa) |
| | CD943_06125 | Unannotated protein. (94 aa) |
| | hisG | Unannotated protein; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (293 aa) |
| | hisD | Unannotated protein; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (435 aa) |
| | hisB | Unannotated protein. (477 aa) |
| | hisH | Unannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (199 aa) |
| | hisA | Unannotated protein. (252 aa) |
| | hisF | Unannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (255 aa) |
| | hisI | Unannotated protein; In the N-terminal section; belongs to the PRA-CH family. (213 aa) |
| | zwf | Unannotated protein; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (484 aa) |
| | pgl | Unannotated protein; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (233 aa) |
| | edd | Unannotated protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (629 aa) |
| | glk | Unannotated protein; Belongs to the bacterial glucokinase family. (322 aa) |
| | CD943_06185 | Unannotated protein. (100 aa) |
| | CD943_06225 | Unannotated protein. (223 aa) |
| | glyA-2 | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (422 aa) |
| | CD943_06500 | Unannotated protein; Belongs to the TPP enzyme family. (554 aa) |
| | hpaIIM_1 | Unannotated protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (382 aa) |
| | argH | Unannotated protein. (441 aa) |
| | lysA | Unannotated protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (424 aa) |
| | CD943_06635 | Unannotated protein. (179 aa) |
| | hisC | Unannotated protein; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (371 aa) |
| | CD943_06715 | Unannotated protein. (409 aa) |
| | CD943_06720 | Unannotated protein. (367 aa) |
| | CD943_06725 | Unannotated protein. (548 aa) |
| | lpdA-2 | Unannotated protein. (465 aa) |
| | ahcY | Unannotated protein; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (487 aa) |
| | tal | Unannotated protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (217 aa) |
| | lpdA-3 | Unannotated protein. (470 aa) |
| | argF | Unannotated protein; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (305 aa) |
| | CD943_07315 | Unannotated protein. (396 aa) |
| | dapE | Unannotated protein; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (397 aa) |
| | CD943_07450 | Unannotated protein. (442 aa) |
| | CD943_07530 | Unannotated protein; Belongs to the folylpolyglutamate synthase family. (428 aa) |
| | trpA | Unannotated protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (280 aa) |
| | trpB | Unannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (404 aa) |
| | trpF | Unannotated protein; Belongs to the TrpF family. (212 aa) |
| | gpmA | Unannotated protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (237 aa) |
| | CD943_07715 | Unannotated protein. (499 aa) |
| | CD943_07725 | Unannotated protein. (428 aa) |
| | glmM | Unannotated protein; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (449 aa) |
| | glmS | Unannotated protein; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (604 aa) |
| | galU | Unannotated protein. (292 aa) |
| | CD943_07835 | Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (328 aa) |
| | OdhB | Unannotated protein; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (501 aa) |
| | CD943_07885 | Unannotated protein. (1006 aa) |
| | sucD | Unannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (300 aa) |
| | sucC | Unannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (396 aa) |
| | CD943_07935 | Unannotated protein; Belongs to the ribulose-phosphate 3-epimerase family. (227 aa) |
| | purH | Unannotated protein. (534 aa) |
| | pgi | Unannotated protein; Belongs to the GPI family. (534 aa) |
| | asd | Unannotated protein; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (348 aa) |
| | mdh | Unannotated protein; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa) |
| | sdhC | Unannotated protein. (153 aa) |
| | CD943_08180 | Unannotated protein. (131 aa) |
| | CD943_08185 | Unannotated protein; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (594 aa) |
| | CD943_08190 | Unannotated protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (265 aa) |
| | CD943_08205 | Unannotated protein. (284 aa) |
| | dapF | Unannotated protein; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (295 aa) |
| | CD943_08260 | Unannotated protein. (768 aa) |
| | acnA | Unannotated protein; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (901 aa) |
| | CD943_08655 | Unannotated protein. (1620 aa) |
| | aroE | Unannotated protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (279 aa) |
| | argG | Unannotated protein; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (409 aa) |
| | CD943_08935 | Unannotated protein; Belongs to the AdoMet synthase family. (399 aa) |
| | CD943_08940 | Unannotated protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (420 aa) |
| | CD943_09105 | Unannotated protein. (324 aa) |
| | pyrF | Unannotated protein; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (240 aa) |
| | GCA_000988015_02772 | Unannotated protein. (323 aa) |
| | thyA | Unannotated protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (285 aa) |
| | CD943_00505 | Unannotated protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (175 aa) |
| | fumC | Unannotated protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa) |
| | dapB | Unannotated protein; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (249 aa) |
| | ppc | Unannotated protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (901 aa) |
| | CD943_09540 | Unannotated protein. (813 aa) |
| | proA | Unannotated protein; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (424 aa) |
| | proB | Unannotated protein; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (389 aa) |
| | leuB-2 | Unannotated protein; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (371 aa) |
| | leuD | Unannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (200 aa) |
| | leuC | Unannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (486 aa) |
| | ilvE_2 | Unannotated protein; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (324 aa) |
| | CD943_09595 | Unannotated protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (415 aa) |
| | CD943_09600 | Unannotated protein. (85 aa) |
| | CD943_09605 | Unannotated protein. (568 aa) |
| | ilvC | Unannotated protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (294 aa) |
