(12 nodes) Signaling, and Glycosyltransferase subfamily 4-like, N-terminal domain network (Rickettsia canadensis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A1E_00340	Preprotein translocase subunit SecB; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (237 aa)
	A1E_01325	COG0642 Signal transduction histidine kinase. (497 aa)
	pleD	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain. (450 aa)
	A1E_01705	Nitrogen regulation protein ntrY; COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation. (600 aa)
	A1E_02110	Nitrogen assimilation regulatory protein NtrX; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. (475 aa)
	A1E_02460	Alkaline phosphatase synthesis sensor protein phor (phor). (93 aa)
	A1E_03220	petR protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (226 aa)
	A1E_03225	Osmolarity sensor protein EnvZ. (468 aa)
	A1E_03285	Hypothetical protein. (67 aa)
	A1E_03290	Hypothetical protein; COG0253 Diaminopimelate epimerase. (26 aa)
	A1E_03295	capM protein; COG0438 Glycosyltransferase. (387 aa)
	A1E_03300	RND efflux system, outer membrane protein. (50 aa)

Your Current Organism:

Rickettsia canadensis

NCBI taxonomy Id: 293613
Other names: R. canadensis str. McKiel, Rickettsia canadensis str. McKiel, Rickettsia canadensis strain McKiel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A1E_00340	A1E_01325	A1E_00340	A1E_01325	Preprotein translocase subunit SecB; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	COG0642 Signal transduction histidine kinase.	0.937
A1E_00340	A1E_01705	A1E_00340	A1E_01705	Preprotein translocase subunit SecB; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	Nitrogen regulation protein ntrY; COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation.	0.782
A1E_00340	A1E_02110	A1E_00340	A1E_02110	Preprotein translocase subunit SecB; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	Nitrogen assimilation regulatory protein NtrX; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.	0.406
A1E_00340	A1E_03225	A1E_00340	A1E_03225	Preprotein translocase subunit SecB; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	Osmolarity sensor protein EnvZ.	0.917
A1E_01325	A1E_00340	A1E_01325	A1E_00340	COG0642 Signal transduction histidine kinase.	Preprotein translocase subunit SecB; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	0.937
A1E_01325	A1E_01705	A1E_01325	A1E_01705	COG0642 Signal transduction histidine kinase.	Nitrogen regulation protein ntrY; COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation.	0.423
A1E_01325	A1E_02110	A1E_01325	A1E_02110	COG0642 Signal transduction histidine kinase.	Nitrogen assimilation regulatory protein NtrX; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.	0.656
A1E_01325	A1E_02460	A1E_01325	A1E_02460	COG0642 Signal transduction histidine kinase.	Alkaline phosphatase synthesis sensor protein phor (phor).	0.526
A1E_01325	A1E_03220	A1E_01325	A1E_03220	COG0642 Signal transduction histidine kinase.	petR protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	0.963
A1E_01325	A1E_03225	A1E_01325	A1E_03225	COG0642 Signal transduction histidine kinase.	Osmolarity sensor protein EnvZ.	0.697
A1E_01325	pleD	A1E_01325	A1E_01370	COG0642 Signal transduction histidine kinase.	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain.	0.998
A1E_01705	A1E_00340	A1E_01705	A1E_00340	Nitrogen regulation protein ntrY; COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation.	Preprotein translocase subunit SecB; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	0.782
A1E_01705	A1E_01325	A1E_01705	A1E_01325	Nitrogen regulation protein ntrY; COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation.	COG0642 Signal transduction histidine kinase.	0.423
A1E_01705	A1E_02110	A1E_01705	A1E_02110	Nitrogen regulation protein ntrY; COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation.	Nitrogen assimilation regulatory protein NtrX; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.	0.985
A1E_01705	A1E_03220	A1E_01705	A1E_03220	Nitrogen regulation protein ntrY; COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation.	petR protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	0.783
A1E_01705	A1E_03225	A1E_01705	A1E_03225	Nitrogen regulation protein ntrY; COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation.	Osmolarity sensor protein EnvZ.	0.491
A1E_01705	pleD	A1E_01705	A1E_01370	Nitrogen regulation protein ntrY; COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation.	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain.	0.411
A1E_02110	A1E_00340	A1E_02110	A1E_00340	Nitrogen assimilation regulatory protein NtrX; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.	Preprotein translocase subunit SecB; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	0.406
A1E_02110	A1E_01325	A1E_02110	A1E_01325	Nitrogen assimilation regulatory protein NtrX; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.	COG0642 Signal transduction histidine kinase.	0.656
A1E_02110	A1E_01705	A1E_02110	A1E_01705	Nitrogen assimilation regulatory protein NtrX; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.	Nitrogen regulation protein ntrY; COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation.	0.985