(6 nodes) Mixed, incl. Zinc-binding ribosomal protein, and Methylation network (Rickettsia akari)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rpsR	30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (95 aa)
	rplS	50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (138 aa)
	rpsL	30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. (129 aa)
	rpsO	30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. (91 aa)
	rpsK	30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (127 aa)
	rpmF	COG0333 Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. (66 aa)

Your Current Organism:

Rickettsia akari

NCBI taxonomy Id: 293614
Other names: R. akari str. Hartford, Rickettsia akari str. Hartford, Rickettsia akari strain Hartford

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
rplS	rpmF	A1C_00845	A1C_06020	50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	COG0333 Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.	0.999
rplS	rpsK	A1C_00845	A1C_04990	50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.	0.999
rplS	rpsL	A1C_00845	A1C_00965	50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.	0.999
rplS	rpsO	A1C_00845	A1C_03565	50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.	0.999
rplS	rpsR	A1C_00845	A1C_00345	50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.	0.999
rpmF	rplS	A1C_06020	A1C_00845	COG0333 Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.	50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.999
rpmF	rpsK	A1C_06020	A1C_04990	COG0333 Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.	30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.	0.999
rpmF	rpsL	A1C_06020	A1C_00965	COG0333 Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.	30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.	0.999
rpmF	rpsO	A1C_06020	A1C_03565	COG0333 Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.	30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.	0.999
rpmF	rpsR	A1C_06020	A1C_00345	COG0333 Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.	30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.	0.999
rpsK	rplS	A1C_04990	A1C_00845	30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.	50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.999
rpsK	rpmF	A1C_04990	A1C_06020	30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.	COG0333 Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.	0.999
rpsK	rpsL	A1C_04990	A1C_00965	30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.	30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.	0.999
rpsK	rpsO	A1C_04990	A1C_03565	30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.	30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.	0.999
rpsK	rpsR	A1C_04990	A1C_00345	30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.	30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.	0.999
rpsL	rplS	A1C_00965	A1C_00845	30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.	50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.999
rpsL	rpmF	A1C_00965	A1C_06020	30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.	COG0333 Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.	0.999
rpsL	rpsK	A1C_00965	A1C_04990	30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.	30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.	0.999
rpsL	rpsO	A1C_00965	A1C_03565	30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.	30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.	0.999
rpsL	rpsR	A1C_00965	A1C_00345	30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.	30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.	0.999