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| | miaA | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (323 aa) |
| | dmlR_30 | HTH-type transcriptional regulator DmlR. (308 aa) |
| | CEL32326.1 | HDOD domain protein. (466 aa) |
| | rpoZ | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (87 aa) |
| | CEL32314.1 | Hypothetical protein. (287 aa) |
| | rph | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (240 aa) |
| | gcvA_12 | Glycine cleavage system transcriptional activator; Belongs to the LysR transcriptional regulatory family. (306 aa) |
| | rnk | Regulator of nucleoside diphosphate kinase. (136 aa) |
| | rho | Hypothetical protein; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (419 aa) |
| | rppH_3 | RNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. (159 aa) |
| | fdx_2 | Ferredoxin. (83 aa) |
| | rsmD | Ribosomal RNA small subunit methyltransferase D; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family. (203 aa) |
| | rpoH | RNA polymerase sigma factor RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. (284 aa) |
| | trmB | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (241 aa) |
| | yqgF | Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. (145 aa) |
| | rsmE | Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (239 aa) |
| | dbpA | ATP-dependent RNA helicase DbpA; Belongs to the DEAD box helicase family. (461 aa) |
| | fecI_8 | Putative RNA polymerase sigma factor FecI; Belongs to the sigma-70 factor family. ECF subfamily. (158 aa) |
| | CEL31909.1 | Hypothetical protein. (213 aa) |
| | rpoD | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (615 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (654 aa) |
| | tsaD | tRNA N6-adenosine threonylcarbamoyltransferase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (341 aa) |
| | cca | Multifunctional CCA protein; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. (407 aa) |
| | apaH | Bis(5'-nucleosyl)-tetraphosphatase, symmetrical; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. (293 aa) |
| | rsmA | Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (272 aa) |
| | vfr | Cyclic AMP receptor-like protein. (214 aa) |
| | tyrS | Tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (399 aa) |
| | nusG | Hypothetical protein; Participates in transcription elongation, termination and antitermination. (177 aa) |
| | rpoB | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1357 aa) |
| | rpoC | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1399 aa) |
| | rpoA | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (333 aa) |
| | nusB | Hypothetical protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (166 aa) |
| | rsmG | Ribosomal RNA small subunit methyltransferase G; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. (214 aa) |
| | mnmG | tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (632 aa) |
| | mnmE | tRNA modification GTPase MnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (456 aa) |
| | rnpA | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (145 aa) |
| | glyS | Glycine--tRNA ligase beta subunit. (684 aa) |
| | glyQ | Glycine--tRNA ligase alpha subunit. (317 aa) |
| | rsmB | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (436 aa) |
| | fmt | Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (319 aa) |
| | tsaC_1 | Threonylcarbamoyl-AMP synthase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. (185 aa) |
| | gcvA_1 | Glycine cleavage system transcriptional activator; Belongs to the LysR transcriptional regulatory family. (316 aa) |
| | gcvA_2 | Glycine cleavage system transcriptional activator; Belongs to the LysR transcriptional regulatory family. (305 aa) |
| | gcvA_3 | Glycine cleavage system transcriptional activator; Belongs to the LysR transcriptional regulatory family. (299 aa) |
| | fecI_1 | Putative RNA polymerase sigma factor FecI. (166 aa) |
| | asnS | Asparagine--tRNA ligase. (309 aa) |
| | sigX | RNA polymerase sigma factor SigX; Belongs to the sigma-70 factor family. ECF subfamily. (203 aa) |
| | yafQ | mRNA interferase YafQ. (104 aa) |
| | vapC | tRNA(fMet)-specific endonuclease VapC. (135 aa) |
| | trmL | tRNA (cytidine(34)-2'-O)-methyltransferase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. (151 aa) |
| | thiI | tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (484 aa) |
| | dtd | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (145 aa) |
| | CEL27105.1 | 16S ribosomal RNA methyltransferase RsmE; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (235 aa) |
| | argS | Arginine--tRNA ligase. (578 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (739 aa) |
| | rlmJ | Ribosomal RNA large subunit methyltransferase J; Specifically methylates the adenine in position 2030 of 23S rRNA. (278 aa) |
| | orn | Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family. (180 aa) |
| | queG | Epoxyqueuosine reductase; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (353 aa) |
| | tsaE | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. (156 aa) |
| | rnr | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (876 aa) |
| | rlmB | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. (255 aa) |
| | dnaB | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (465 aa) |
| | gcvA_4 | Glycine cleavage system transcriptional activator; Belongs to the LysR transcriptional regulatory family. (300 aa) |
| | gcvA_5 | Glycine cleavage system transcriptional activator. (315 aa) |
| | dusC_1 | tRNA-dihydrouridine synthase C; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. (336 aa) |
| | ubiG_1 | Ubiquinone biosynthesis O-methyltransferase; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs; Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family. (249 aa) |
| | dmlR_1 | HTH-type transcriptional regulator DmlR; Belongs to the LysR transcriptional regulatory family. (309 aa) |
| | dmlR_2 | HTH-type transcriptional regulator DmlR; Belongs to the LysR transcriptional regulatory family. (303 aa) |
| | yhbY | RNA-binding protein YhbY. (102 aa) |
| | rlmE | Ribosomal RNA large subunit methyltransferase E; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (209 aa) |
| | nusA | Hypothetical protein; Participates in both transcription termination and antitermination. (493 aa) |
| | rbfA | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (133 aa) |
| | truB | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (305 aa) |
| | pnp | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (701 aa) |
| | rng | Ribonuclease G. (485 aa) |
| | rpoN | RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (489 aa) |
| | gcvA_6 | Glycine cleavage system transcriptional activator; Belongs to the LysR transcriptional regulatory family. (315 aa) |
| | fecI_2 | Putative RNA polymerase sigma factor FecI; Belongs to the sigma-70 factor family. ECF subfamily. (162 aa) |
| | fecI_3 | Putative RNA polymerase sigma factor FecI; Belongs to the sigma-70 factor family. ECF subfamily. (188 aa) |
| | rhlB | ATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. (492 aa) |
| | rlmF | Ribosomal RNA large subunit methyltransferase F; Specifically methylates the adenine in position 1618 of 23S rRNA. (339 aa) |
| | valS | Valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (948 aa) |
| | rnc | Ribonuclease 3; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (208 aa) |
| | rimM | Ribosome maturation factor RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (178 aa) |
| | trmD | tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (250 aa) |
| | tcdA | tRNA threonylcarbamoyladenosine dehydratase. (272 aa) |
| | rnhB | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (208 aa) |
| | tilS | tRNA(Ile)-lysidine synthase. (442 aa) |
| | truD | tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. (352 aa) |
| | rpoS | RNA polymerase sigma factor RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. (336 aa) |
| | CEL27864.1 | DTW domain protein. (249 aa) |
| | tsaA_1 | Putative tRNA (adenine(37)-N6)-methyltransferase. (232 aa) |
| | rluF | Ribosomal large subunit pseudouridine synthase F. (236 aa) |
| | rimO_2 | Ribosomal protein S12 methylthiotransferase RimO; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (445 aa) |
| | proS | Proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] (571 aa) |
| | dmlR_6 | HTH-type transcriptional regulator DmlR; Belongs to the LysR transcriptional regulatory family. (301 aa) |
| | CEL27984.1 | Hypothetical protein. (114 aa) |
| | rsuA | Ribosomal small subunit pseudouridine synthase A; Belongs to the pseudouridine synthase RsuA family. (230 aa) |
| | rpoE_1 | ECF RNA polymerase sigma-E factor; Belongs to the sigma-70 factor family. ECF subfamily. (193 aa) |
| | CEL28040.1 | Hypothetical protein. (63 aa) |
| | rnd | Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. (377 aa) |
| | CEL28051.1 | SpoU rRNA Methylase family protein. (156 aa) |
| | hrpB_1 | ATP-dependent RNA helicase HrpB. (1303 aa) |
| | rpoE_2 | ECF RNA polymerase sigma-E factor; Belongs to the sigma-70 factor family. ECF subfamily. (204 aa) |
| | CEL28111.1 | DTW domain protein. (199 aa) |
| | dnaE2_1 | Error-prone DNA polymerase. (287 aa) |
| | tsaC_2 | Threonylcarbamoyl-AMP synthase; Belongs to the SUA5 family. (222 aa) |
| | rluB | Ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family. (405 aa) |
| | ntrC | Nitrogen assimilation regulatory protein. (491 aa) |
| | fliA | RNA polymerase sigma factor FliA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. (246 aa) |
| | gcvA_7 | Glycine cleavage system transcriptional activator. (308 aa) |
| | rluA_1 | Ribosomal large subunit pseudouridine synthase A. (211 aa) |
| | dmlR_7 | HTH-type transcriptional regulator DmlR; Belongs to the LysR transcriptional regulatory family. (323 aa) |
| | sigW | ECF RNA polymerase sigma factor SigW; Belongs to the sigma-70 factor family. ECF subfamily. (196 aa) |
| | rlmL | Ribosomal RNA large subunit methyltransferase K/L; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. (756 aa) |
| | fecI_4 | Putative RNA polymerase sigma factor FecI; Belongs to the sigma-70 factor family. ECF subfamily. (159 aa) |
| | gltX | Glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (493 aa) |
| | dusC_2 | tRNA-dihydrouridine synthase C; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. (319 aa) |
| | truA | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (284 aa) |
| | csrA | Hypothetical protein; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). (64 aa) |
| | thrS | Threonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). (640 aa) |
| | pheS | Phenylalanine--tRNA ligase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (338 aa) |
| | pheT | Phenylalanine--tRNA ligase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (792 aa) |
| | dmlR_10 | HTH-type transcriptional regulator DmlR. (299 aa) |
| | rnhA | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (153 aa) |
| | dmlR_11 | HTH-type transcriptional regulator DmlR. (307 aa) |
| | trmK | tRNA (adenine(22)-N(1))-methyltransferase. (242 aa) |
| | dmlR_12 | HTH-type transcriptional regulator DmlR. (297 aa) |
| | dmlR_13 | HTH-type transcriptional regulator DmlR. (296 aa) |
| | dmlR_17 | HTH-type transcriptional regulator DmlR. (297 aa) |
| | dmlR_18 | HTH-type transcriptional regulator DmlR. (305 aa) |
| | CEL29126.1 | Putative acetyltransferase. (311 aa) |
| | selA | L-seryl-tRNA(Sec) selenium transferase. (470 aa) |
| | fecI_5 | Putative RNA polymerase sigma factor FecI; Belongs to the sigma-70 factor family. ECF subfamily. (169 aa) |
| | dmlR_20 | HTH-type transcriptional regulator DmlR. (306 aa) |
| | dmlR_21 | HTH-type transcriptional regulator DmlR. (294 aa) |
| | dmlR_22 | HTH-type transcriptional regulator DmlR. (296 aa) |
| | sigR | ECF RNA polymerase sigma factor SigR. (137 aa) |
| | traC_4 | DNA primase TraC. (292 aa) |
| | CEL31712.1 | Hypothetical protein. (508 aa) |
| | rlmH | Ribosomal RNA large subunit methyltransferase H; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (155 aa) |
| | leuS | Leucine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (868 aa) |
| | ybeY | Endoribonuclease YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (164 aa) |
| | miaB | (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (442 aa) |
| | rluE | Ribosomal large subunit pseudouridine synthase E; Belongs to the pseudouridine synthase RsuA family. (211 aa) |
| | hrpB_2 | ATP-dependent RNA helicase HrpB. (839 aa) |
| | CEL31600.1 | NYN domain protein. (159 aa) |
| | rhlE_2 | ATP-dependent RNA helicase RhlE; Belongs to the DEAD box helicase family. (445 aa) |
| | trmA | tRNA/tmRNA (uracil-C(5))-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA). (359 aa) |
| | rlmG | Ribosomal RNA large subunit methyltransferase G; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. (374 aa) |
| | greA_3 | Transcription elongation factor GreA. (168 aa) |
| | ileS | Isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (943 aa) |
| | rluD | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (320 aa) |
| | rlmI_1 | Ribosomal RNA large subunit methyltransferase I; Belongs to the methyltransferase superfamily. (338 aa) |
| | pcnB | Poly(A) polymerase I precursor; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (466 aa) |
| | gluQ | Glutamyl-Q tRNA(Asp) synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (298 aa) |
| | rsmC | Ribosomal RNA small subunit methyltransferase C; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family. (332 aa) |
| | trpS | Tryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (451 aa) |
| | rsmI | Ribosomal RNA small subunit methyltransferase I; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (290 aa) |
| | rsmH | Ribosomal RNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (315 aa) |
| | tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (377 aa) |
| | trmJ | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. (256 aa) |
| | rlmN | Dual-specificity RNA methyltransferase RlmN; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (382 aa) |
| | rodZ | Cytoskeleton protein RodZ. (344 aa) |
| | hisS | Histidine--tRNA ligase. (429 aa) |
| | tadA | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (165 aa) |
| | cmoB | tRNA (mo5U34)-methyltransferase; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs. (318 aa) |
| | cmoA_2 | tRNA (cmo5U34)-methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM). (247 aa) |
| | lysU | Lysine--tRNA ligase, heat inducible; Belongs to the class-II aminoacyl-tRNA synthetase family. (500 aa) |
| | betI_1 | HTH-type transcriptional regulator BetI. (238 aa) |
| | tsaB | tRNA threonylcarbamoyladenosine biosynthesis protein TsaB. (224 aa) |
| | rsmJ | Ribosomal RNA small subunit methyltransferase J; Specifically methylates the guanosine in position 1516 of 16S rRNA. (260 aa) |
| | ybaK_2 | Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (156 aa) |
| | rnt_2 | Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. (225 aa) |
| | metG | Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (683 aa) |
| | gcvA_11 | Glycine cleavage system transcriptional activator. (293 aa) |
| | sbcB | Exodeoxyribonuclease I. (476 aa) |
| | aspS | Aspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (591 aa) |
| | sigE | ECF RNA polymerase sigma factor SigE; Belongs to the sigma-70 factor family. ECF subfamily. (175 aa) |
| | CEL30903.1 | RNA polymerase sigma factor; Belongs to the sigma-70 factor family. (414 aa) |
| | alaS_2 | Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (872 aa) |
| | csrA-2 | Hypothetical protein; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). (62 aa) |
| | ttcA | tRNA 2-thiocytidine biosynthesis protein TtcA; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (274 aa) |
| | rlmD | 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. (466 aa) |
| | alaS_1 | Alanine--tRNA ligase. (208 aa) |
| | dmlR_27 | HTH-type transcriptional regulator DmlR; Belongs to the LysR transcriptional regulatory family. (332 aa) |
| | rne | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (1083 aa) |
| | rluC | Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (353 aa) |
| | CEL30719.1 | Putative hydrolase. (217 aa) |
| | CEL30691.1 | Hypothetical protein; Carbon storage regulator homolog. (61 aa) |
| | mnmC_2 | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. (659 aa) |
| | CEL30678.1 | Transcriptional regulator BolA; Belongs to the BolA/IbaG family. (99 aa) |
| | glpE_2 | Thiosulfate sulfurtransferase GlpE; Belongs to the UPF0176 family. (313 aa) |
| | deaD | ATP-dependent RNA helicase DeaD; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (557 aa) |
| | rluA_2 | Ribosomal large subunit pseudouridine synthase A. (307 aa) |
| | fecI_7 | Putative RNA polymerase sigma factor FecI; Belongs to the sigma-70 factor family. ECF subfamily. (184 aa) |
| | rlmM | Ribosomal RNA large subunit methyltransferase M; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. (357 aa) |
| | tusA_2 | Sulfurtransferase TusA; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family. (83 aa) |
| | dus | Putative tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. (328 aa) |
| | CEL30363.1 | Ribonuclease T2 family protein. (221 aa) |
| | fecI_6 | Putative RNA polymerase sigma factor FecI. (163 aa) |
| | selU | tRNA 2-selenouridine synthase. (367 aa) |
| | sigK | ECF RNA polymerase sigma factor SigK. (182 aa) |
| | ampR_2 | HTH-type transcriptional activator AmpR; Belongs to the LysR transcriptional regulatory family. (288 aa) |
| | sigH | ECF RNA polymerase sigma factor SigH; Belongs to the sigma-70 factor family. ECF subfamily. (168 aa) |
| | glnS | Glutamine--tRNA ligase. (565 aa) |
| | cysS | Cysteine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (460 aa) |
| | CEL30120.1 | Ribonuclease VapC22. (125 aa) |
| | mnmA | tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (374 aa) |
| | serS | Serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (426 aa) |
| | tusE | Sulfurtransferase TusE; Part of a sulfur-relay system. (111 aa) |
| | tusB | Protein TusB. (97 aa) |
| | dsrF | Intracellular sulfur oxidation protein DsrF. (118 aa) |
| | dsrE | Putative sulfurtransferase DsrE. (130 aa) |
| | rebM_2 | Demethylrebeccamycin-D-glucose O-methyltransferase. (349 aa) |
| | CEL29865.1 | Putative DNA ligase-like protein/MT0965. (866 aa) |
| | CEL29831.1 | tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE). (202 aa) |
| | ybaK_1 | Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK. (159 aa) |
| | gcvA_9 | Glycine cleavage system transcriptional activator. (285 aa) |
| | CEL29663.1 | RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (183 aa) |
