node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
fumC_1 | fumC_2 | SRM1_00896 | SRM1_04039 | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.412 |
fumC_1 | gltA_1 | SRM1_00896 | SRM1_01606 | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Citrate synthase; Belongs to the citrate synthase family. | 0.489 |
fumC_1 | prpC | SRM1_00896 | SRM1_01852 | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 2-methylcitrate synthase; Belongs to the citrate synthase family. | 0.489 |
fumC_1 | sucA | SRM1_00896 | SRM1_01611 | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 2-oxoglutarate dehydrogenase E1 component. | 0.460 |
fumC_1 | sucD | SRM1_00896 | SRM1_01615 | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.587 |
fumC_2 | fumC_1 | SRM1_04039 | SRM1_00896 | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.412 |
fumC_2 | gltA_1 | SRM1_04039 | SRM1_01606 | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Citrate synthase; Belongs to the citrate synthase family. | 0.489 |
fumC_2 | prpC | SRM1_04039 | SRM1_01852 | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 2-methylcitrate synthase; Belongs to the citrate synthase family. | 0.489 |
fumC_2 | sucA | SRM1_04039 | SRM1_01611 | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 2-oxoglutarate dehydrogenase E1 component. | 0.460 |
fumC_2 | sucD | SRM1_04039 | SRM1_01615 | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.587 |
gltA_1 | fumC_1 | SRM1_01606 | SRM1_00896 | Citrate synthase; Belongs to the citrate synthase family. | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.489 |
gltA_1 | fumC_2 | SRM1_01606 | SRM1_04039 | Citrate synthase; Belongs to the citrate synthase family. | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.489 |
gltA_1 | sucA | SRM1_01606 | SRM1_01611 | Citrate synthase; Belongs to the citrate synthase family. | 2-oxoglutarate dehydrogenase E1 component. | 0.854 |
gltA_1 | sucD | SRM1_01606 | SRM1_01615 | Citrate synthase; Belongs to the citrate synthase family. | Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.680 |
prpC | fumC_1 | SRM1_01852 | SRM1_00896 | 2-methylcitrate synthase; Belongs to the citrate synthase family. | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.489 |
prpC | fumC_2 | SRM1_01852 | SRM1_04039 | 2-methylcitrate synthase; Belongs to the citrate synthase family. | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.489 |
prpC | sucA | SRM1_01852 | SRM1_01611 | 2-methylcitrate synthase; Belongs to the citrate synthase family. | 2-oxoglutarate dehydrogenase E1 component. | 0.781 |
prpC | sucD | SRM1_01852 | SRM1_01615 | 2-methylcitrate synthase; Belongs to the citrate synthase family. | Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.696 |
sucA | fumC_1 | SRM1_01611 | SRM1_00896 | 2-oxoglutarate dehydrogenase E1 component. | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.460 |
sucA | fumC_2 | SRM1_01611 | SRM1_04039 | 2-oxoglutarate dehydrogenase E1 component. | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.460 |