STRINGSTRING
CEL27024.1 CEL27024.1 hisB hisB hisH1 hisH1 hisA hisA hisF hisF CEL27084.1 CEL27084.1 hutU hutU hutH_1 hutH_1 hutH_2 hutH_2 hutI hutI CEL27095.1 CEL27095.1 hisE hisE hisI hisI cmdF cmdF hisZ hisZ gabD gabD hisG hisG hisD hisD hisC hisC CEL28058.1 CEL28058.1 gbsA_1 gbsA_1 CEL29468.1 CEL29468.1 CEL29469.1 CEL29469.1 CEL29470.1 CEL29470.1 betB_1 betB_1 hisC2 hisC2 CEL31474.1 CEL31474.1 pao pao calB calB CEL32503.1 CEL32503.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CEL27024.1Hypothetical protein. (248 aa)
hisBImidazoleglycerol-phosphate dehydratase. (197 aa)
hisH1Imidazole glycerol phosphate synthase subunit HisH 1; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (212 aa)
hisA1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (249 aa)
hisFImidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (256 aa)
CEL27084.18-oxoguanine deaminase. (454 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (566 aa)
hutH_1Histidine ammonia-lyase. (507 aa)
hutH_2Histidine ammonia-lyase; Belongs to the PAL/histidase family. (510 aa)
hutIImidazolonepropionase. (401 aa)
CEL27095.1N-formylglutamate amidohydrolase. (267 aa)
hisEPhosphoribosyl-ATP pyrophosphatase. (110 aa)
hisIPhosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (133 aa)
cmdFTyrosine 2,3-aminomutase. (514 aa)
hisZATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (395 aa)
gabDSuccinate-semialdehyde dehydrogenase [NADP(+)]; Belongs to the aldehyde dehydrogenase family. (496 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (211 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (441 aa)
hisCHistidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (350 aa)
CEL28058.1Glutamine amidotransferases class-II. (258 aa)
gbsA_1Betaine aldehyde dehydrogenase. (487 aa)
CEL29468.1Hypothetical protein. (286 aa)
CEL29469.1Hypothetical protein. (313 aa)
CEL29470.1Hypothetical protein. (197 aa)
betB_1NAD/NADP-dependent betaine aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (493 aa)
hisC2Histidinol-phosphate aminotransferase 2; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (370 aa)
CEL31474.1Hypothetical protein; TfoX C-terminal domain. (90 aa)
paoPseudooxynicotine oxidase. (591 aa)
calBConiferyl aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (476 aa)
CEL32503.1Transposase IS116/IS110/IS902 family protein. (315 aa)
Your Current Organism:
Pseudomonas fluorescens
NCBI taxonomy Id: 294
Other names: ATCC 13525, Bacillus fluorescens, Bacillus fluorescens liquefaciens, Bacterium fluorescen, CCEB 546, CFBP 2102, CIP 69.13, DSM 50090, IAM 12022, IFO 14160, JCM 5963, Liquidomonas fluorescens, NBRC 14160, NCCB 76040, NCIB 9046, NCIB:9046, NCIMB 9046, NCTC 10038, NRRL B-14678, P. fluorescens, Pseudomonas sp. AU2390, Pseudomonas sp. BZ64, Pseudomonas sp. FY32, Pseudomonas sp. HSA2/2016, Pseudomonas sp. HSA3/2016, Pseudomonas sp. ISSDS-433, Pseudomonas sp. JCM 17186, Pseudomonas sp. JCM 2779, Pseudomonas sp. KH-20150KS3, Pseudomonas sp. LBUM223, Pseudomonas sp. LBUM636, Pseudomonas sp. SM2/2016, RH 818, VKM B-894, bacterium P1-1, strain M. Rhodes 28/5
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