STRINGSTRING
ispE ispE anmK anmK APR68991.1 APR68991.1 thiL thiL phoR phoR APR69063.1 APR69063.1 APR69064.1 APR69064.1 thrB thrB APR69133.1 APR69133.1 aroK aroK gmk gmk ackA ackA ndk ndk APR69434.1 APR69434.1 APR69458.1 APR69458.1 APR69460.1 APR69460.1 APR69491.1 APR69491.1 APR69530.1 APR69530.1 APR69570.1 APR69570.1 APR69589.1 APR69589.1 APR69590.1 APR69590.1 lpdA lpdA fruK fruK fruB fruB tmk tmk proB proB AHTJS_05260 AHTJS_05260 APR69885.1 APR69885.1 prkC_2 prkC_2 APR70045.1 APR70045.1 thiM thiM pgk pgk APR70182.1 APR70182.1 APR70219.1 APR70219.1 pyrH pyrH APR70237.1 APR70237.1 APR70249.1 APR70249.1 AHTJS_07555 AHTJS_07555 APR70307.1 APR70307.1 eno eno APR70400.1 APR70400.1 cmk cmk lpxK lpxK APR70461.1 APR70461.1 fda fda APR70477.1 APR70477.1 nadK nadK APR70551.1 APR70551.1 AHTJS_09395 AHTJS_09395 APR70578.1 APR70578.1 ubiB_4 ubiB_4 ydiA ydiA ppsA ppsA APR70661.1 APR70661.1 AHTJS_10660 AHTJS_10660 adk adk ppk ppk APR70898.1 APR70898.1 APR70923.1 APR70923.1 glpK glpK argB argB prs prs APR71042.1 APR71042.1 coaX coaX APR71120.1 APR71120.1 APR71217.1 APR71217.1 APR71227.1 APR71227.1 APR71269.1 APR71269.1 APR71281.1 APR71281.1 APR71320.1 APR71320.1 APR71414.1 APR71414.1 APR71418.1 APR71418.1 APR71432.1 APR71432.1 APR71453.1 APR71453.1 AHTJS_14705 AHTJS_14705 APR71482.1 APR71482.1 tpiA tpiA coaE coaE APR71555.1 APR71555.1 APR71573.1 APR71573.1 gpmI gpmI APR71595.1 APR71595.1 APR71613.1 APR71613.1 APR71626.1 APR71626.1 APR71677.1 APR71677.1 pgi pgi APR71776.1 APR71776.1 ribF ribF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ispE4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (277 aa)
anmKanhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (377 aa)
APR68991.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
thiLThiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (305 aa)
phoRPhosphate regulon sensor histidine kinase PhoR; Derived by automated computational analysis using gene prediction method: Protein Homology. (451 aa)
APR69063.1Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (905 aa)
APR69064.1Pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (656 aa)
thrBHomoserine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudomonas-type ThrB family. (316 aa)
APR69133.1Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa)
aroKShikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (180 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (207 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (143 aa)
APR69434.1Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (423 aa)
APR69458.1Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (558 aa)
APR69460.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
APR69491.1Adenylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
APR69530.1Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (1693 aa)
APR69570.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (878 aa)
APR69589.1Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (444 aa)
APR69590.1Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa)
lpdADihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa)
fruK1-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. (316 aa)
fruBPhosphoenolpyruvate--protein phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (950 aa)
tmkdTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (201 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (377 aa)
AHTJS_05260Transposase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (87 aa)
APR69885.1Protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
prkC_2Protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (574 aa)
APR70045.1Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (442 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (271 aa)
pgkPhosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (395 aa)
APR70182.1DUF4440 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (159 aa)
APR70219.1PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (369 aa)
pyrHUMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (242 aa)
APR70237.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)
APR70249.1Bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (172 aa)
AHTJS_07555Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa)
APR70307.1Toxin HipA; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (429 aa)
APR70400.1Adenosine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
cmkCytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (335 aa)
APR70461.1Phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
fdaFructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (345 aa)
APR70477.1Phosphatidylinositol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (409 aa)
nadKNAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (314 aa)
APR70551.1Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa)
AHTJS_09395Transposase; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (98 aa)
APR70578.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa)
ubiB_4Kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (432 aa)
ydiAPhosphoenolpyruvate synthase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. (278 aa)
ppsAPhosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (792 aa)
APR70661.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (426 aa)
AHTJS_10660Integrase; Incomplete; partial on complete genome; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. (1080 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (217 aa)
ppkPolyphosphate kinase 1; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (692 aa)
APR70898.1Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (124 aa)
APR70923.1Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (504 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (299 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (317 aa)
APR71042.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
coaXPantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (247 aa)
APR71120.1Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (546 aa)
APR71217.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (162 aa)
APR71227.1Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (936 aa)
APR71269.1Two-component sensor histidine kinase; Member of a two-component regulatory system. (458 aa)
APR71281.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (98 aa)
APR71320.1Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (687 aa)
APR71414.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (72 aa)
APR71418.1Phosphoenolpyruvate--protein phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. (764 aa)
APR71432.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)
APR71453.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (578 aa)
AHTJS_14705Citrate-proton symporter; Is involved in the uptake of citrate and the transport of protons into the cell; incomplete; partial on complete genome; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. (472 aa)
APR71482.12-octaprenylphenol hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (539 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (263 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (201 aa)
APR71555.1Alginate biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
APR71573.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (521 aa)
gpmIPhosphoglycerate mutase (2,3-diphosphoglycerate-independent); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (514 aa)
APR71595.1Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (460 aa)
APR71613.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (114 aa)
APR71626.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (98 aa)
APR71677.1Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (1171 aa)
pgiGlucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (557 aa)
APR71776.1Tyrosine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (728 aa)
ribFRiboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (333 aa)
Your Current Organism:
Acinetobacter haemolyticus
NCBI taxonomy Id: 29430
Other names: A. haemolyticus, ATCC 17906, Achromobacter haemolyticus, Acinetobacter genomosp. 4, Acinetobacter genomospecies 4, Acinetobacter haematolyticus, CCUG 888, CIP 64.3, DSM 6962, LMG 996, LMG:996, NCCB 85026, NCTC 12155, NCTC:12155, strain B40, strain Mannheim 2446/60
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