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sucD sucD asd asd APR71311.1 APR71311.1 APR71309.1 APR71309.1 APR71308.1 APR71308.1 APR71306.1 APR71306.1 pntA-1 pntA-1 APR71229.1 APR71229.1 APR71221.1 APR71221.1 proC proC APR71064.1 APR71064.1 fabG fabG APR71388.1 APR71388.1 mdh_1 mdh_1 AHTJS_13870 AHTJS_13870 ilvC ilvC APR71312.1 APR71312.1 hemA hemA APR70978.1 APR70978.1 APR70968.1 APR70968.1 APR70967.1 APR70967.1 APR70961.1 APR70961.1 APR70954.1 APR70954.1 folD folD pdxB pdxB APR70818.1 APR70818.1 APR71959.1 APR71959.1 sahH sahH APR70659.1 APR70659.1 APR70584.1 APR70584.1 aroA aroA aroE aroE AHTJS_01710 AHTJS_01710 acr1 acr1 APR69142.1 APR69142.1 APR71863.1 APR71863.1 APR69050.1 APR69050.1 APR69017.1 APR69017.1 APR68972.1 APR68972.1 dapB dapB APR70030.1 APR70030.1 APR70029.1 APR70029.1 nadX nadX APR69895.1 APR69895.1 APR69889.1 APR69889.1 ktrA ktrA APR70356.1 APR70356.1 APR70354.1 APR70354.1 APR70345.1 APR70345.1 APR70272.1 APR70272.1 dxr dxr APR70209.1 APR70209.1 gpsA gpsA fabG_5 fabG_5 AHTJS_06775 AHTJS_06775 APR70081.1 APR70081.1 APR70070.1 APR70070.1 APR70052.1 APR70052.1 APR69870.1 APR69870.1 cysG cysG APR69601.1 APR69601.1 APR69489.1 APR69489.1 APR69436.1 APR69436.1 APR69391.1 APR69391.1 APR69279.1 APR69279.1 APR71831.1 APR71831.1 APR71790.1 APR71790.1 APR71772.1 APR71772.1 APR71767.1 APR71767.1 APR71766.1 APR71766.1 APR71765.1 APR71765.1 APR71761.1 APR71761.1 APR71759.1 APR71759.1 APR71748.1 APR71748.1 mmsB mmsB APR71601.1 APR71601.1 APR71597.1 APR71597.1 APR71570.1 APR71570.1 fadB fadB APR71467.1 APR71467.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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sucDsuccinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (296 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (372 aa)
APR71311.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (246 aa)
APR71309.1NADPH:quinone reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
APR71308.1Quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)
APR71306.1S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (370 aa)
pntA-1NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
APR71229.13-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)
APR71221.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (258 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (279 aa)
APR71064.1Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa)
fabGbeta-ketoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (244 aa)
APR71388.1Sodium:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (571 aa)
mdh_1Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (328 aa)
AHTJS_13870Hypothetical protein; Incomplete; partial on complete genome; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa)
APR71312.1Zn-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. (332 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (427 aa)
APR70978.1TIGR01777 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
APR70968.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
APR70967.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa)
APR70961.1Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (423 aa)
APR70954.1Malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; Derived by automated computational analysis using gene prediction method: Protein Homology. (566 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (280 aa)
pdxBErythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate. (355 aa)
APR70818.1Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (448 aa)
APR71959.1NADP-dependent malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (756 aa)
sahHAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (460 aa)
APR70659.1Erythrose-4-phosphate dehydrogenase; NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (341 aa)
APR70584.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (256 aa)
aroABifunctional prephenate dehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (749 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (262 aa)
AHTJS_01710Peptidase M23; Incomplete; partial on complete genome; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (410 aa)
acr1Fatty acyl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (295 aa)
APR69142.1NAD-dependent epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
APR71863.1Short chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
APR69050.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
APR69017.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (275 aa)
APR68972.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (273 aa)
APR70030.1Short chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (275 aa)
APR70029.1Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (423 aa)
nadXAspartate dehydrogenase; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. (263 aa)
APR69895.1Short chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (264 aa)
APR69889.1Short-chain dehydrogenase; Member of a large family of NAD or NADP-dependent oxidoreductases; paralogs occur in many bacteria; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
ktrAPotassium transporter TrkA; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)
APR70356.1NAD(P)H-quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
APR70354.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (333 aa)
APR70345.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (276 aa)
APR70272.13-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
dxr1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (398 aa)
APR70209.1UDP-glucose 4-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
gpsAGlycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (357 aa)
fabG_53-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (463 aa)
AHTJS_0677530S ribosomal protein S20; Incomplete; partial on complete genome; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
APR70081.1Potassium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (610 aa)
APR70070.1F420-dependent NADP oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
APR70052.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (274 aa)
APR69870.1Bifunctional glyoxylate/hydroxypyruvate reductase B; Catalyzes the formation of glycolate from glyoxylate and glycerate from hydroxypyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (321 aa)
cysGuroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (451 aa)
APR69601.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (268 aa)
APR69489.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (711 aa)
APR69436.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
APR69391.12,4-dienoyl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
APR69279.1NAD(P)-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa)
APR71831.1Short chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (247 aa)
APR71790.1YciK family oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
APR71772.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
APR71767.1UDP-glucose 4-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
APR71766.1Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
APR71765.1NAD-dependent epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
APR71761.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (419 aa)
APR71759.1UDP-glucose 4-epimerase GalE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (338 aa)
APR71748.1Dihydrodipicolinate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapB family. (260 aa)
mmsB3-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HIBADH-related family. (296 aa)
APR71601.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
APR71597.1Sugar dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
APR71570.1Homoserine dehydrogenase; Catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
fadBMultifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (717 aa)
APR71467.1Potassium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (605 aa)
Your Current Organism:
Acinetobacter haemolyticus
NCBI taxonomy Id: 29430
Other names: A. haemolyticus, ATCC 17906, Achromobacter haemolyticus, Acinetobacter genomosp. 4, Acinetobacter genomospecies 4, Acinetobacter haematolyticus, CCUG 888, CIP 64.3, DSM 6962, LMG 996, LMG:996, NCCB 85026, NCTC 12155, NCTC:12155, strain B40, strain Mannheim 2446/60
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