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| | truD | tRNA pseudouridine synthase D TruD; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. (452 aa) |
| | YLM1_1802 | PHP domain-containing protein. (397 aa) |
| | leuS | leucyl-tRNA synthetase LeuS; Belongs to the class-I aminoacyl-tRNA synthetase family. (957 aa) |
| | YLM1_1787 | tRNA(1-methyladenosine) methyltransferase. (243 aa) |
| | rps15 | Ribosomal protein S15P Rps15p. (132 aa) |
| | YLM1_1719 | Universal archaeal protein Kae1/Bud32; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. (546 aa) |
| | YLM1_1717 | LSM domain-containing protein. (65 aa) |
| | argS | arginyl-tRNA synthetase ArgS; Belongs to the class-I aminoacyl-tRNA synthetase family. (573 aa) |
| | YLM1_1696 | Signal peptidase I. (141 aa) |
| | thrS | threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (607 aa) |
| | gatA | Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit A GatA; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (461 aa) |
| | YLM1_1630 | GNAT family acetyltransferase. (155 aa) |
| | YLM1_1614 | Hypothetical protein. (163 aa) |
| | YLM1_1605 | Archaeal histone. (67 aa) |
| | YLM1_1572 | tRNA-dihydrouridine synthase DusA. (324 aa) |
| | YLM1_1571 | Methanogeneis marker protein 11. (312 aa) |
| | ileS | isoleucyl-tRNA synthetase IleS; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1136 aa) |
| | rsmA | Dimethyladenosine transferase KsgA; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. (300 aa) |
| | YLM1_1516 | DNA-directed RNA polymerase subunit F RpoF. (116 aa) |
| | rpl21e | Ribosomal protein L21e Rpl21e; Belongs to the eukaryotic ribosomal protein eL21 family. (96 aa) |
| | pus10 | Pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. (424 aa) |
| | csl4 | Exosome complex RNA-binding protein Csl4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. (188 aa) |
| | rpoL | DNA-directed RNA polymerase subunit L RpoL; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. (90 aa) |
| | YLM1_1508 | Transcription factor S Tfs; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (111 aa) |
| | rpl44e | Ribosomal protein L44e Rpl44e; Binds to the 23S rRNA. (92 aa) |
| | rps27e | Ribosomal protein S27e Rps27e. (59 aa) |
| | eif2a | Translation initiation factor aIF-2 alpha subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. (260 aa) |
| | nop10 | H/ACA RNA-protein complex component Nop10p; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (56 aa) |
| | YLM1_1485 | Hypothetical protein. (166 aa) |
| | YLM1_1474 | GNAT family acetyltransferase. (213 aa) |
| | gatB | Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit B GatB; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (451 aa) |
| | flpA | Fibrillarin FlpA; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (223 aa) |
| | taw2 | Met-10+ like-protein; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7- aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe). (254 aa) |
| | trm1 | N2,N2-dimethylguanosine tRNA methyltransferase Trm1; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (403 aa) |
| | YLM1_1404 | PP-loop family protein. (283 aa) |
| | YLM1_1397 | seryl-tRNA synthetase SerS. (425 aa) |
| | rpl10e | Ribosomal protein L10e Rpl10e; Belongs to the universal ribosomal protein uL16 family. (160 aa) |
| | YLM1_1348 | tRNA ribose 2'-O-methyltransferase; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. (185 aa) |
| | YLM1_1341 | Hypothetical protein; Belongs to the LarC family. (424 aa) |
| | YLM1_1326 | Hydrogenase expression/formation protein HypD. (350 aa) |
| | eif1a | Translation initiation factor aIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (101 aa) |
| | YLM1_1318 | RNA-binding protein. (200 aa) |
| | YLM1_1303 | tRNA-dihydrouridine synthase DusA. (237 aa) |
| | taw1 | tRNA-modifying enzyme; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). (304 aa) |
| | rpoH | DNA-directed RNA polymerase subunit H RpoH; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (82 aa) |
| | YLM1_1277 | DNA-directed RNA polymerase subunit B'' RpoB2; Belongs to the RNA polymerase beta chain family. (519 aa) |
| | YLM1_1276 | DNA-directed RNA polymerase subunit B' RpoB1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (603 aa) |
| | YLM1_1275 | DNA-directed RNA polymerase subunit A' RpoA1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (934 aa) |
| | rpoA2 | DNA-directed RNA polymerase subunit A'' RpoA2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (557 aa) |
| | rpl30e | Ribosomal protein L30e Rpl30e; Belongs to the eukaryotic ribosomal protein eL30 family. (94 aa) |
| | nusA | Transcription elongation factor NusA-like protein; Participates in transcription termination. Belongs to the NusA family. (125 aa) |
| | rps12 | Ribosomal protein S12P Rps12p; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (141 aa) |
| | rps7 | Ribosomal protein S7P Rps7p; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (186 aa) |
| | fusA | Translation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...] (724 aa) |
| | tuf | Translation elongation factor aEF-1 alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (413 aa) |
| | rps10 | Ribosomal protein S10P Rps10p; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (101 aa) |
| | YLM1_1260 | Ribosomal-protein-alanine acetyltransferase RimI. (148 aa) |
| | YLM1_1227 | Met-10+ like-protein. (365 aa) |
| | YLM1_1213 | Thioesterase family protein. (132 aa) |
| | eif5a | Translation initiation factor aIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (135 aa) |
| | YLM1_1187 | Archaeal histone. (67 aa) |
| | truA | tRNA pseudouridine synthase A TruA; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. (291 aa) |
| | YLM1_1156 | Hypothetical protein. (210 aa) |
| | YLM1_1155 | MiaB-like tRNA modifying enzyme. (424 aa) |
| | YLM1_1154 | Archaeal histone. (66 aa) |
| | YLM1_1152 | Histone acetyltransferase ELP3 family. (568 aa) |
| | rps17e | Ribosomal protein S17e Rps17e; Belongs to the eukaryotic ribosomal protein eS17 family. (65 aa) |
| | hypA-2 | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (127 aa) |
| | YLM1_1122 | Hydrogenase accessory protein HypB. (225 aa) |
| | hypA | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (120 aa) |
| | YLM1_1081 | Transcription initiation factor TFIIB Tfb. (339 aa) |
| | pheT | phenylalanyl-tRNA synthetase beta subunit PheT. (551 aa) |
| | valS | valyl-tRNA synthetase ValS; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (920 aa) |
| | cysS | cysteinyl-tRNA synthetase CysS; Belongs to the class-I aminoacyl-tRNA synthetase family. (486 aa) |
| | pheS | phenylalanyl-tRNA synthetase alpha subunit PheS; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (515 aa) |
| | rps8e | Ribosomal protein S8e Rps8e. (125 aa) |
| | YLM1_1037 | Hydrogenase maturation factor HypE. (336 aa) |
| | YLM1_1009 | Hypothetical protein. (406 aa) |
| | tgtA | Archaeosine tRNA-ribosyltransferase TgtA; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (667 aa) |
| | YLM1_0996 | tRNA intron endonuclease EndA. (195 aa) |
| | trpS | tryptophanyl-tRNA synthetase TrpS; Catalyzes the attachment of tryptophan to tRNA(Trp). (363 aa) |
| | YLM1_0991 | Archaeal histone. (65 aa) |
| | rpl7ae | Ribosomal protein L7Ae Rpl7ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (135 aa) |
| | rps28e | Ribosomal protein S28e Rps28e; Belongs to the eukaryotic ribosomal protein eS28 family. (68 aa) |
| | rpl24e | Ribosomal protein L24e Rpl24e; Binds to the 23S rRNA. (53 aa) |
| | infB | Translation initiation factor aIF-2 InfB; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (595 aa) |
| | rps6e | Ribosomal protein S6e Rps6e; Belongs to the eukaryotic ribosomal protein eS6 family. (128 aa) |
| | eif2g | Translation initiation factor aIF-2 gamma subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (407 aa) |
| | YLM1_0982 | DNA-directed RNA polymerase subunit E' RpoE1. (194 aa) |
| | rps24e | Ribosomal protein S24e Rps24e; Belongs to the eukaryotic ribosomal protein eS24 family. (105 aa) |
| | rps27ae | Ribosomal protein S27ae Rps27ae; Belongs to the eukaryotic ribosomal protein eS31 family. (52 aa) |
| | YLM1_0942 | RNA methylase. (344 aa) |
| | gatD | glutamyl-tRNA(Gln) amidotransferase subunit D GatD; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (435 aa) |
| | gatE | glutamyl-tRNA(Gln) amidotransferase subunit E GatE; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (648 aa) |
| | YLM1_0913 | Hypothetical protein. (175 aa) |
| | rpl15e | Ribosomal protein L15e Rpl15e; Belongs to the eukaryotic ribosomal protein eL15 family. (183 aa) |
| | rnp3 | Ribonuclease P subunit P30; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family. (296 aa) |
| | rnp2 | Ribonuclease P subunit P14; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 2 family. (127 aa) |
| | rpl37ae | Ribosomal protein L37Ae Rpl37ae; Binds to the 23S rRNA. (89 aa) |
| | YLM1_0838 | DNA-directed RNA polymerase subunit P RpoP 847a. (43 aa) |
| | YLM1_0837 | Ribosomal biogeneis protein; Probably involved in the biogenesis of the ribosome. (163 aa) |
| | YLM1_0836 | Hypothetical protein. (104 aa) |
| | YLM1_0796 | RNA-binding protein. (158 aa) |
| | YLM1_0794 | Hypothetical protein. (128 aa) |
| | YLM1_0793 | LSM domain-containing protein; Belongs to the snRNP Sm proteins family. (77 aa) |
| | rpl37e | Ribosomal protein L37e Rpl37e 800a; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (61 aa) |
| | YLM1_0773 | Hypothetical protein. (344 aa) |
| | YLM1_0767 | Hypothetical protein; Probable pre-rRNA processing protein involved in ribosome biogenesis; Belongs to the TSR3 family. (172 aa) |
| | rpl40e | Ribosomal protein L40e Rpl40e; Belongs to the eukaryotic ribosomal protein eL40 family. (48 aa) |
| | YLM1_0742 | DNA helicase. (2252 aa) |
| | YLM1_0737 | Hypothetical protein. (573 aa) |
| | YLM1_0678 | Ribonuclease III Rnc. (222 aa) |
| | hisS | histidyl-tRNA synthetase HisS; Belongs to the class-II aminoacyl-tRNA synthetase family. (431 aa) |
| | YLM1_0596 | Deoxyhypusine synthase Dys. (312 aa) |
| | YLM1_0588 | Hypothetical protein. (589 aa) |
| | YLM1_0579 | HEAT repeat-containing protein. (155 aa) |
| | aspS | aspartyl-tRNA synthetase AspS; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (440 aa) |
| | cca | tRNA nucleotidyltransferase Cca; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (494 aa) |
| | metG | methionyl-tRNA synthetase MetG; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (680 aa) |
| | proS | prolyl-tRNA synthetase ProS; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (468 aa) |
| | gltX | glutamyl-tRNA synthetase GltX; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (556 aa) |
| | rps2 | Ribosomal protein S2P Rps2p; Belongs to the universal ribosomal protein uS2 family. (198 aa) |
| | YLM1_0480 | DNA-directed RNA polymerase subunit K RpoK. (72 aa) |
| | YLM1_0479 | DNA-directed RNA polymerase subunit N RpoN. (56 aa) |
| | rps9 | Ribosomal protein S9P Rps9p; Belongs to the universal ribosomal protein uS9 family. (132 aa) |
| | rpl13 | Ribosomal protein L13P Rpl13p; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (142 aa) |
| | rpl18e | Ribosomal protein L18e Rpl18e; Belongs to the eukaryotic ribosomal protein eL18 family. (121 aa) |
| | rpoD | DNA-directed RNA polymerase subunit D RpoD; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (275 aa) |
| | rps11 | Ribosomal protein S11P Rps11p; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (130 aa) |
| | rps4 | Ribosomal protein S4P Rps4p; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (178 aa) |
| | rps13 | Ribosomal protein S13P Rps13p; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (148 aa) |
| | truB | H/ACA RNA-protein complex component Cbf5p; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (320 aa) |
| | YLM1_0466 | Ribosomal protein L14e Rpl14e. (55 aa) |
| | rpl34e | Ribosomal protein L34e Rpl34e; Belongs to the eukaryotic ribosomal protein eL34 family. (88 aa) |
| | rpl15 | Ribosomal protein L15P Rpl15p; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (145 aa) |
| | rpl30 | Ribosomal protein L30P Rpl30p. (152 aa) |
| | rps5 | Ribosomal protein S5P Rps5p; With S4 and S12 plays an important role in translational accuracy. (213 aa) |
| | rpl18 | Ribosomal protein L18P Rpl18p; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (193 aa) |
| | rpl19e | Ribosomal protein L19e Rpl19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (148 aa) |
| | YLM1_0455 | Ribosomal protein L32e Rpl32e. (108 aa) |
| | rpl6 | Ribosomal protein L6P Rpl6p; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa) |
| | rps8 | Ribosomal protein S8P Rps8p; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa) |
| | rps14 | Ribosomal protein S14P Rps14p; Binds 16S rRNA, required for the assembly of 30S particles. (48 aa) |
| | rpl5 | Ribosomal protein L5P Rpl5p; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (173 aa) |
| | rps4e | Ribosomal protein S4e Rps4e; Belongs to the eukaryotic ribosomal protein eS4 family. (244 aa) |
| | rpl24 | Ribosomal protein L24P Rpl24p; Located at the polypeptide exit tunnel on the outside of the subunit. (114 aa) |
| | rpl14 | Ribosomal protein L14P Rpl14p; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (135 aa) |
| | rps17 | Ribosomal protein S17P Rps17p; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (106 aa) |
| | rnp1 | Ribonuclease P subunit P29; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 1 family. (118 aa) |
| | YLM1_0445 | Translation initiation factor aSUI1; Belongs to the SUI1 family. (114 aa) |
| | rpl29 | Ribosomal protein L29P Rpl29p; Belongs to the universal ribosomal protein uL29 family. (68 aa) |
| | rps3 | Ribosomal protein S3P Rps3p; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (253 aa) |
| | rpl22 | Ribosomal protein L22P Rpl22p; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (156 aa) |
| | rps19p | Ribosomal protein S19P Rps19p; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (136 aa) |
| | rpl2 | Ribosomal protein L2P Rpl2p; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (241 aa) |
| | rpl23 | Ribosomal protein L23P Rpl23p; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (86 aa) |
| | rpl4 | Ribosomal protein L4p Rpl4p; Forms part of the polypeptide exit tunnel. (254 aa) |
| | rpl3 | Ribosomal protein L3P Rpl3p; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (336 aa) |
| | YLM1_0427 | Fibronectin-binding A domain-containing protein. (670 aa) |
| | YLM1_0402 | Archaeosine tRNA-ribosyltransferase TgtA. (244 aa) |
| | prf1 | Peptide chain release factor aRF1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (414 aa) |
| | tfb | Transcription initiation factor TFIIB Tfb1; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (264 aa) |
| | tiaS | DNA-binding protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. (417 aa) |
| | YLM1_0321 | tRNA(His) guanylyltransferase ThgL. (259 aa) |
| | YLM1_0315 | tRNA binding domain-containing protein. (241 aa) |
| | YLM1_0293 | RNA methyltransferase TrmH family. (263 aa) |
| | YLM1_0290 | glycyl-tRNA synthetase GlyS. (570 aa) |
| | rnz | Ribonuclease Z Rnz; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (317 aa) |
| | rlmE | Ribosomal RNA large subunit methyltransferase J RrmJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (208 aa) |
| | eif2b | Translation initiation factor aIF-2 beta subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (135 aa) |
| | tyrS | tyrosyl-tRNA synthetase TyrS; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily. (321 aa) |
| | YLM1_0232 | Radical SAM domain-containing protein. (362 aa) |
| | YLM1_0226 | PP-loop family protein. (325 aa) |
| | YLM1_0213 | Transcription factor S Tfs; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (105 aa) |
| | ef1b | Translation elongation factor aEF-1 beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (89 aa) |
| | YLM1_0182 | peptidyl-tRNA hydrolase. (112 aa) |
| | YLM1_0180 | ATPase RIL. (591 aa) |
| | YLM1_0177 | Sua5/YciO/YrdC/YwlC family translation factor. (220 aa) |
| | thiI | Thiamine biosynthesis ATP pyrophosphatase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (382 aa) |
| | alaS | alanyl-tRNA synthetase AlaS; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (908 aa) |
| | rpl12 | Ribosomal protein L12P Rpl12p; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (105 aa) |
| | rpl10 | Acidic ribosomal protein P0 RplPO; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (334 aa) |
| | rpl1 | Ribosomal protein L1P Rpl1p; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (212 aa) |
| | rpl11 | Ribosomal protein L11P Rpl11p; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (160 aa) |
| | spt5 | Ribosomal protein L24 family; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (163 aa) |
| | tfe | Transcription initiation factor TFIIE alpha subunit Tfe; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabili [...] (381 aa) |
| | YLM1_0148 | RNA-binding protein. (303 aa) |
| | YLM1_0146 | Hydrogenase assembly chaperone HypC. (82 aa) |
| | rps3ae | Ribosomal protein S3Ae Rps3ae; Belongs to the eukaryotic ribosomal protein eS1 family. (193 aa) |
| | YLM1_0098 | Hypothetical protein. (329 aa) |
| | rtcB | tRNA-splicing ligase RtcB family protein; Belongs to the RtcB family. (482 aa) |
| | YLM1_0092 | Hypothetical protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. (160 aa) |
| | rpl18a | Ribosomal protein LX RplX. (74 aa) |
| | eif6 | Translation initiation factor aIF-6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (225 aa) |
| | rpl31e | Ribosomal protein L31e Rpl31e; Belongs to the ribosomal protein L31e family. (86 aa) |
| | rpl39e | Ribosomal protein L39e Rpl39e; Belongs to the eukaryotic ribosomal protein eL39 family. (51 aa) |
| | rps19e | Ribosomal protein S19e Rps19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (146 aa) |
| | YLM1_0067 | RNA-binding protein. (88 aa) |
| | rnp4 | Ribonuclease P subunit RPR2; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (123 aa) |
| | YLM1_0064 | GTP-binding protein. (364 aa) |
| | tbp | TATA-box binding protein Tbp; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (181 aa) |
| | lysS | lysyl-tRNA synthetase LysS; Belongs to the class-I aminoacyl-tRNA synthetase family. (527 aa) |
| | YLM1_0007 | CAAX amino terminal protease family protein. (272 aa) |
