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MED5 | Mediator of RNA polymerase II transcription subunit 5; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (663 aa) | ||||
PGUG_00134 | BSD domain-containing protein. (620 aa) | ||||
PGUG_00259 | DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. (1144 aa) | ||||
PGUG_00298 | BTP domain-containing protein. (263 aa) | ||||
MED11 | Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (134 aa) | ||||
PGUG_00366 | Uncharacterized protein. (274 aa) | ||||
PGUG_00402 | Plus3 domain-containing protein. (539 aa) | ||||
PGUG_00409 | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1166 aa) | ||||
MED4 | Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (288 aa) | ||||
TAF4 | Transcription initiation factor TFIID subunit 4; Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of tra [...] (455 aa) | ||||
PGUG_00438 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (123 aa) | ||||
PGUG_00445 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (112 aa) | ||||
PGUG_00612 | CYCLIN domain-containing protein; Belongs to the cyclin family. (383 aa) | ||||
PGUG_00670 | Protein kinase domain-containing protein. (665 aa) | ||||
PGUG_00695 | Uncharacterized protein. (339 aa) | ||||
PGUG_00714 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (563 aa) | ||||
PGUG_00729 | FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (546 aa) | ||||
MED17 | Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (573 aa) | ||||
PGUG_00814 | Uncharacterized protein. (305 aa) | ||||
PGUG_00968 | Uncharacterized protein. (699 aa) | ||||
PGUG_01036 | Uncharacterized protein. (213 aa) | ||||
PGUG_01107 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (288 aa) | ||||
RPB1 | DNA-directed RNA polymerase II subunit RPB1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cl [...] (1579 aa) | ||||
PGUG_01264 | CYCLIN domain-containing protein; Belongs to the cyclin family. (292 aa) | ||||
PGUG_01286 | Uncharacterized protein. (930 aa) | ||||
PGUG_01300 | TAF domain-containing protein. (489 aa) | ||||
PGUG_01313 | TFIID_20kDa domain-containing protein. (515 aa) | ||||
PGUG_01357 | Uncharacterized protein. (383 aa) | ||||
PGUG_01395 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (111 aa) | ||||
PGUG_01402 | CID domain-containing protein. (303 aa) | ||||
PGUG_01460 | RPOL4c domain-containing protein. (188 aa) | ||||
MED8 | Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (213 aa) | ||||
PGUG_01495 | Protein kinase domain-containing protein. (435 aa) | ||||
MED10 | Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (144 aa) | ||||
PGUG_01774 | Uncharacterized protein. (239 aa) | ||||
PGUG_01783 | Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (269 aa) | ||||
PGUG_01872 | DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (148 aa) | ||||
PGUG_02002 | Uncharacterized protein; Belongs to the cyclin family. (335 aa) | ||||
PGUG_02014 | Uncharacterized protein. (288 aa) | ||||
PGUG_02050 | DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (306 aa) | ||||
PGUG_02059 | Uncharacterized protein. (1601 aa) | ||||
PGUG_02088 | Uncharacterized protein. (380 aa) | ||||
PGUG_02191 | HTH CENPB-type domain-containing protein. (541 aa) | ||||
PGUG_02223 | TAF8_C domain-containing protein. (529 aa) | ||||
PGUG_02226 | RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (732 aa) | ||||
PGUG_02308 | Uncharacterized protein; Belongs to the cytochrome P450 family. (567 aa) | ||||
PGUG_02408 | Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (532 aa) | ||||
PGUG_02475 | Uncharacterized protein. (186 aa) | ||||
PGUG_02478 | TAFII55_N domain-containing protein. (501 aa) | ||||
PGUG_02490 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (331 aa) | ||||
MED18 | Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (287 aa) | ||||
PGUG_02659 | Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (229 aa) | ||||
PGUG_02765 | DNA-directed RNA polymerases II 24 kDa polypeptide. (179 aa) | ||||
MED6 | Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (301 aa) | ||||
PGUG_02831 | Uncharacterized protein. (173 aa) | ||||
RPB2 | DNA-directed RNA polymerase II subunit RPB2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB2 is [...] (1236 aa) | ||||
PGUG_02865 | NDC10_II domain-containing protein. (636 aa) | ||||
PGUG_02891 | Uncharacterized protein. (216 aa) | ||||
PGUG_03017 | RPOL4c domain-containing protein. (148 aa) | ||||
PGUG_03049 | Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (112 aa) | ||||
PGUG_03110 | Uncharacterized protein. (1056 aa) | ||||
PGUG_03179 | Uncharacterized protein. (309 aa) | ||||
PGUG_03348 | Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (970 aa) | ||||
PGUG_03363 | Uncharacterized protein. (609 aa) | ||||
PGUG_03419 | Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (116 aa) | ||||
PGUG_03501 | Uncharacterized protein. (1074 aa) | ||||
PGUG_03608 | HTH TFE/IIEalpha-type domain-containing protein. (380 aa) | ||||
PGUG_03680 | RING-type domain-containing protein. (321 aa) | ||||
PGUG_03709 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1632 aa) | ||||
PGUG_03759 | Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (119 aa) | ||||
PGUG_03770 | Med12 domain-containing protein. (1561 aa) | ||||
PGUG_03796 | Uncharacterized protein. (378 aa) | ||||
PGUG_03882 | SANT domain-containing protein. (586 aa) | ||||
PGUG_04032 | RNA_pol_L_2 domain-containing protein. (123 aa) | ||||
PGUG_04052 | Uncharacterized protein. (72 aa) | ||||
PGUG_04089 | GATA-type domain-containing protein. (539 aa) | ||||
PGUG_04095 | RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (498 aa) | ||||
PGUG_04096 | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1156 aa) | ||||
MED20 | Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (236 aa) | ||||
PGUG_04106 | Uncharacterized protein. (356 aa) | ||||
PGUG_04108 | CYCLIN domain-containing protein; Belongs to the cyclin family. (385 aa) | ||||
PGUG_04123 | Uncharacterized protein. (1004 aa) | ||||
PGUG_04142 | GCR1_C domain-containing protein. (304 aa) | ||||
PGUG_04158 | Uncharacterized protein. (210 aa) | ||||
PGUG_04298 | TATA-box binding protein. (240 aa) | ||||
PGUG_04303 | Helicase ATP-binding domain-containing protein. (843 aa) | ||||
PGUG_04305 | Uncharacterized protein. (373 aa) | ||||
PGUG_04343 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1379 aa) | ||||
PGUG_04398 | HMG box domain-containing protein. (253 aa) | ||||
PGUG_04733 | DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. (1303 aa) | ||||
PGUG_04749 | CDC73_C domain-containing protein. (373 aa) | ||||
PGUG_04799 | Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (97 aa) | ||||
PGUG_04842 | Zn(2)-C6 fungal-type domain-containing protein. (614 aa) | ||||
PGUG_04924 | Uncharacterized protein. (650 aa) | ||||
PGUG_04942 | General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (488 aa) | ||||
PGUG_04943 | Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (963 aa) | ||||
PGUG_04948 | Mediator of RNA polymerase II transcription subunit 13; Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. (1561 aa) | ||||
CHL1 | ATP-dependent DNA helicase CHL1; ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity). (825 aa) | ||||
PGUG_04989 | Uncharacterized protein. (73 aa) | ||||
PGUG_05071 | Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (211 aa) | ||||
PGUG_05134 | Uncharacterized protein. (415 aa) | ||||
PGUG_05245 | HMG box domain-containing protein. (90 aa) | ||||
PGUG_05248 | Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (123 aa) | ||||
PGUG_05271 | rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (385 aa) | ||||
PGUG_05316 | RPOLD domain-containing protein. (333 aa) | ||||
PGUG_05344 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (476 aa) | ||||
PGUG_05395 | RPOLD domain-containing protein. (305 aa) | ||||
PGUG_05425 | Uncharacterized protein. (158 aa) | ||||
PGUG_05450 | Uncharacterized protein. (840 aa) | ||||
RPC82 | DNA-directed RNA polymerase III subunit RPC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (By similarity). (588 aa) | ||||
PGUG_05490 | TFIIS N-terminal domain-containing protein. (364 aa) | ||||
PGUG_05504 | Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (170 aa) | ||||
PGUG_05526 | Uncharacterized protein. (194 aa) | ||||
PGUG_05580 | TAFII28 domain-containing protein. (241 aa) | ||||
MED16 | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (941 aa) | ||||
PGUG_05648 | Uncharacterized protein. (410 aa) | ||||
PGUG_05809 | Uncharacterized protein. (453 aa) | ||||
PGUG_05819 | Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1442 aa) | ||||
PGUG_05851 | Uncharacterized protein. (69 aa) |