STRINGSTRING
MED5 MED5 PGUG_00134 PGUG_00134 PGUG_00259 PGUG_00259 PGUG_00298 PGUG_00298 MED11 MED11 PGUG_00366 PGUG_00366 PGUG_00402 PGUG_00402 PGUG_00409 PGUG_00409 MED4 MED4 TAF4 TAF4 PGUG_00438 PGUG_00438 PGUG_00445 PGUG_00445 PGUG_00612 PGUG_00612 PGUG_00670 PGUG_00670 PGUG_00695 PGUG_00695 PGUG_00714 PGUG_00714 PGUG_00729 PGUG_00729 MED17 MED17 PGUG_00814 PGUG_00814 PGUG_00968 PGUG_00968 PGUG_01036 PGUG_01036 PGUG_01107 PGUG_01107 RPB1 RPB1 PGUG_01264 PGUG_01264 PGUG_01286 PGUG_01286 PGUG_01300 PGUG_01300 PGUG_01313 PGUG_01313 PGUG_01357 PGUG_01357 PGUG_01395 PGUG_01395 PGUG_01402 PGUG_01402 PGUG_01460 PGUG_01460 MED8 MED8 PGUG_01495 PGUG_01495 MED10 MED10 PGUG_01774 PGUG_01774 PGUG_01783 PGUG_01783 PGUG_01872 PGUG_01872 PGUG_02002 PGUG_02002 PGUG_02014 PGUG_02014 PGUG_02050 PGUG_02050 PGUG_02059 PGUG_02059 PGUG_02088 PGUG_02088 PGUG_02191 PGUG_02191 PGUG_02223 PGUG_02223 PGUG_02226 PGUG_02226 PGUG_02308 PGUG_02308 PGUG_02408 PGUG_02408 PGUG_02475 PGUG_02475 PGUG_02478 PGUG_02478 PGUG_02490 PGUG_02490 MED18 MED18 PGUG_02659 PGUG_02659 PGUG_02765 PGUG_02765 MED6 MED6 PGUG_02831 PGUG_02831 RPB2 RPB2 PGUG_02865 PGUG_02865 PGUG_02891 PGUG_02891 PGUG_03017 PGUG_03017 PGUG_03049 PGUG_03049 PGUG_03110 PGUG_03110 PGUG_03179 PGUG_03179 PGUG_03348 PGUG_03348 PGUG_03363 PGUG_03363 PGUG_03419 PGUG_03419 PGUG_03501 PGUG_03501 PGUG_03608 PGUG_03608 PGUG_03680 PGUG_03680 PGUG_03709 PGUG_03709 PGUG_03759 PGUG_03759 PGUG_03770 PGUG_03770 PGUG_03796 PGUG_03796 PGUG_03882 PGUG_03882 PGUG_04032 PGUG_04032 PGUG_04052 PGUG_04052 PGUG_04089 PGUG_04089 PGUG_04095 PGUG_04095 PGUG_04096 PGUG_04096 MED20 MED20 PGUG_04106 PGUG_04106 PGUG_04108 PGUG_04108 PGUG_04123 PGUG_04123 PGUG_04142 PGUG_04142 PGUG_04158 PGUG_04158 PGUG_04298 PGUG_04298 PGUG_04303 PGUG_04303 PGUG_04305 PGUG_04305 PGUG_04343 PGUG_04343 PGUG_04398 PGUG_04398 PGUG_04733 PGUG_04733 PGUG_04749 PGUG_04749 PGUG_04799 PGUG_04799 PGUG_04842 PGUG_04842 PGUG_04924 PGUG_04924 PGUG_04942 PGUG_04942 PGUG_04943 PGUG_04943 PGUG_04948 PGUG_04948 CHL1 CHL1 PGUG_04989 PGUG_04989 PGUG_05071 PGUG_05071 PGUG_05134 PGUG_05134 PGUG_05245 PGUG_05245 PGUG_05248 PGUG_05248 PGUG_05271 PGUG_05271 PGUG_05316 PGUG_05316 PGUG_05344 PGUG_05344 PGUG_05395 PGUG_05395 PGUG_05425 PGUG_05425 PGUG_05450 PGUG_05450 RPC82 RPC82 PGUG_05490 PGUG_05490 PGUG_05504 PGUG_05504 PGUG_05526 PGUG_05526 PGUG_05580 PGUG_05580 MED16 MED16 PGUG_05648 PGUG_05648 PGUG_05809 PGUG_05809 PGUG_05819 PGUG_05819 PGUG_05851 PGUG_05851
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
MED5Mediator of RNA polymerase II transcription subunit 5; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (663 aa)
PGUG_00134BSD domain-containing protein. (620 aa)
PGUG_00259DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. (1144 aa)
PGUG_00298BTP domain-containing protein. (263 aa)
MED11Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (134 aa)
PGUG_00366Uncharacterized protein. (274 aa)
PGUG_00402Plus3 domain-containing protein. (539 aa)
PGUG_00409DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1166 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (288 aa)
TAF4Transcription initiation factor TFIID subunit 4; Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of tra [...] (455 aa)
PGUG_00438DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (123 aa)
PGUG_00445DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (112 aa)
PGUG_00612CYCLIN domain-containing protein; Belongs to the cyclin family. (383 aa)
PGUG_00670Protein kinase domain-containing protein. (665 aa)
PGUG_00695Uncharacterized protein. (339 aa)
PGUG_00714Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (563 aa)
PGUG_00729FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (546 aa)
MED17Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (573 aa)
PGUG_00814Uncharacterized protein. (305 aa)
PGUG_00968Uncharacterized protein. (699 aa)
PGUG_01036Uncharacterized protein. (213 aa)
PGUG_01107DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (288 aa)
RPB1DNA-directed RNA polymerase II subunit RPB1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cl [...] (1579 aa)
PGUG_01264CYCLIN domain-containing protein; Belongs to the cyclin family. (292 aa)
PGUG_01286Uncharacterized protein. (930 aa)
PGUG_01300TAF domain-containing protein. (489 aa)
PGUG_01313TFIID_20kDa domain-containing protein. (515 aa)
PGUG_01357Uncharacterized protein. (383 aa)
PGUG_01395DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (111 aa)
PGUG_01402CID domain-containing protein. (303 aa)
PGUG_01460RPOL4c domain-containing protein. (188 aa)
MED8Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (213 aa)
PGUG_01495Protein kinase domain-containing protein. (435 aa)
MED10Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (144 aa)
PGUG_01774Uncharacterized protein. (239 aa)
PGUG_01783Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (269 aa)
PGUG_01872DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (148 aa)
PGUG_02002Uncharacterized protein; Belongs to the cyclin family. (335 aa)
PGUG_02014Uncharacterized protein. (288 aa)
PGUG_02050DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (306 aa)
PGUG_02059Uncharacterized protein. (1601 aa)
PGUG_02088Uncharacterized protein. (380 aa)
PGUG_02191HTH CENPB-type domain-containing protein. (541 aa)
PGUG_02223TAF8_C domain-containing protein. (529 aa)
PGUG_02226RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (732 aa)
PGUG_02308Uncharacterized protein; Belongs to the cytochrome P450 family. (567 aa)
PGUG_02408Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (532 aa)
PGUG_02475Uncharacterized protein. (186 aa)
PGUG_02478TAFII55_N domain-containing protein. (501 aa)
PGUG_02490Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (331 aa)
MED18Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (287 aa)
PGUG_02659Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (229 aa)
PGUG_02765DNA-directed RNA polymerases II 24 kDa polypeptide. (179 aa)
MED6Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (301 aa)
PGUG_02831Uncharacterized protein. (173 aa)
RPB2DNA-directed RNA polymerase II subunit RPB2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB2 is [...] (1236 aa)
PGUG_02865NDC10_II domain-containing protein. (636 aa)
PGUG_02891Uncharacterized protein. (216 aa)
PGUG_03017RPOL4c domain-containing protein. (148 aa)
PGUG_03049Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (112 aa)
PGUG_03110Uncharacterized protein. (1056 aa)
PGUG_03179Uncharacterized protein. (309 aa)
PGUG_03348Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (970 aa)
PGUG_03363Uncharacterized protein. (609 aa)
PGUG_03419Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (116 aa)
PGUG_03501Uncharacterized protein. (1074 aa)
PGUG_03608HTH TFE/IIEalpha-type domain-containing protein. (380 aa)
PGUG_03680RING-type domain-containing protein. (321 aa)
PGUG_03709DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1632 aa)
PGUG_03759Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (119 aa)
PGUG_03770Med12 domain-containing protein. (1561 aa)
PGUG_03796Uncharacterized protein. (378 aa)
PGUG_03882SANT domain-containing protein. (586 aa)
PGUG_04032RNA_pol_L_2 domain-containing protein. (123 aa)
PGUG_04052Uncharacterized protein. (72 aa)
PGUG_04089GATA-type domain-containing protein. (539 aa)
PGUG_04095RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (498 aa)
PGUG_04096DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1156 aa)
MED20Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (236 aa)
PGUG_04106Uncharacterized protein. (356 aa)
PGUG_04108CYCLIN domain-containing protein; Belongs to the cyclin family. (385 aa)
PGUG_04123Uncharacterized protein. (1004 aa)
PGUG_04142GCR1_C domain-containing protein. (304 aa)
PGUG_04158Uncharacterized protein. (210 aa)
PGUG_04298TATA-box binding protein. (240 aa)
PGUG_04303Helicase ATP-binding domain-containing protein. (843 aa)
PGUG_04305Uncharacterized protein. (373 aa)
PGUG_04343DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1379 aa)
PGUG_04398HMG box domain-containing protein. (253 aa)
PGUG_04733DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. (1303 aa)
PGUG_04749CDC73_C domain-containing protein. (373 aa)
PGUG_04799Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (97 aa)
PGUG_04842Zn(2)-C6 fungal-type domain-containing protein. (614 aa)
PGUG_04924Uncharacterized protein. (650 aa)
PGUG_04942General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (488 aa)
PGUG_04943Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (963 aa)
PGUG_04948Mediator of RNA polymerase II transcription subunit 13; Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. (1561 aa)
CHL1ATP-dependent DNA helicase CHL1; ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity). (825 aa)
PGUG_04989Uncharacterized protein. (73 aa)
PGUG_05071Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (211 aa)
PGUG_05134Uncharacterized protein. (415 aa)
PGUG_05245HMG box domain-containing protein. (90 aa)
PGUG_05248Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (123 aa)
PGUG_05271rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (385 aa)
PGUG_05316RPOLD domain-containing protein. (333 aa)
PGUG_05344Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (476 aa)
PGUG_05395RPOLD domain-containing protein. (305 aa)
PGUG_05425Uncharacterized protein. (158 aa)
PGUG_05450Uncharacterized protein. (840 aa)
RPC82DNA-directed RNA polymerase III subunit RPC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (By similarity). (588 aa)
PGUG_05490TFIIS N-terminal domain-containing protein. (364 aa)
PGUG_05504Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (170 aa)
PGUG_05526Uncharacterized protein. (194 aa)
PGUG_05580TAFII28 domain-containing protein. (241 aa)
MED16Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (941 aa)
PGUG_05648Uncharacterized protein. (410 aa)
PGUG_05809Uncharacterized protein. (453 aa)
PGUG_05819Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1442 aa)
PGUG_05851Uncharacterized protein. (69 aa)
Your Current Organism:
Meyerozyma guilliermondii
NCBI taxonomy Id: 294746
Other names: M. guilliermondii ATCC 6260, Meyerozyma guilliermondii ATCC 6260, Pichia guilliermondii ATCC 6260
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