(18 nodes) Homologous recombination, and Single-stranded DNA endodeoxyribonuclease activity network (Meyerozyma guilliermondii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PGUG_00649	AAA_23 domain-containing protein. (1302 aa)
	PGUG_00892	Uncharacterized protein. (378 aa)
	PGUG_01392	Uncharacterized protein. (888 aa)
	PGUG_01500	RMI1_N domain-containing protein. (174 aa)
	PGUG_01790	RECA_2 domain-containing protein. (504 aa)
	PGUG_02378	Uncharacterized protein. (830 aa)
	PGUG_02715	Uncharacterized protein. (1155 aa)
	PGUG_02862	Uncharacterized protein. (1403 aa)
	PGUG_02934	ERCC4 domain-containing protein. (601 aa)
	PGUG_02937	Uncharacterized protein. (423 aa)
	PGUG_03677	Uncharacterized protein. (635 aa)
	PGUG_03869	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (333 aa)
	PGUG_04172	Uncharacterized protein. (169 aa)
	PGUG_04191	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (641 aa)
	PGUG_04361	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (616 aa)
	PGUG_04837	Uncharacterized protein. (1176 aa)
	PGUG_05249	Uncharacterized protein. (1133 aa)
	PGUG_05597	Uncharacterized protein. (814 aa)

Your Current Organism:

Meyerozyma guilliermondii

NCBI taxonomy Id: 294746
Other names: M. guilliermondii ATCC 6260, Meyerozyma guilliermondii ATCC 6260, Pichia guilliermondii ATCC 6260

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PGUG_00649	PGUG_00892	A5DBJ4	A5DC87	AAA_23 domain-containing protein.	Uncharacterized protein.	0.481
PGUG_00649	PGUG_01392	A5DBJ4	A5DDP1	AAA_23 domain-containing protein.	Uncharacterized protein.	0.421
PGUG_00649	PGUG_01500	A5DBJ4	A5DDZ9	AAA_23 domain-containing protein.	RMI1_N domain-containing protein.	0.778
PGUG_00649	PGUG_01790	A5DBJ4	A5DET9	AAA_23 domain-containing protein.	RECA_2 domain-containing protein.	0.742
PGUG_00649	PGUG_02378	A5DBJ4	A5DGH7	AAA_23 domain-containing protein.	Uncharacterized protein.	0.563
PGUG_00649	PGUG_02862	A5DBJ4	A5DHW1	AAA_23 domain-containing protein.	Uncharacterized protein.	0.723
PGUG_00649	PGUG_02934	A5DBJ4	A5DI33	AAA_23 domain-containing protein.	ERCC4 domain-containing protein.	0.673
PGUG_00649	PGUG_02937	A5DBJ4	A5DI36	AAA_23 domain-containing protein.	Uncharacterized protein.	0.894
PGUG_00649	PGUG_03677	A5DBJ4	A5DK76	AAA_23 domain-containing protein.	Uncharacterized protein.	0.839
PGUG_00649	PGUG_03869	A5DBJ4	A5DKR8	AAA_23 domain-containing protein.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.887
PGUG_00649	PGUG_04172	A5DBJ4	A5DLM1	AAA_23 domain-containing protein.	Uncharacterized protein.	0.735
PGUG_00649	PGUG_04191	A5DBJ4	A5DLP0	AAA_23 domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.999
PGUG_00649	PGUG_04361	A5DBJ4	A5DM60	AAA_23 domain-containing protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.867
PGUG_00649	PGUG_04837	A5DBJ4	A5DNI6	AAA_23 domain-containing protein.	Uncharacterized protein.	0.938
PGUG_00649	PGUG_05249	A5DBJ4	A5DPP8	AAA_23 domain-containing protein.	Uncharacterized protein.	0.786
PGUG_00649	PGUG_05597	A5DBJ4	A5DQP6	AAA_23 domain-containing protein.	Uncharacterized protein.	0.499
PGUG_00892	PGUG_00649	A5DC87	A5DBJ4	Uncharacterized protein.	AAA_23 domain-containing protein.	0.481
PGUG_00892	PGUG_01392	A5DC87	A5DDP1	Uncharacterized protein.	Uncharacterized protein.	0.439
PGUG_00892	PGUG_01790	A5DC87	A5DET9	Uncharacterized protein.	RECA_2 domain-containing protein.	0.647
PGUG_00892	PGUG_02378	A5DC87	A5DGH7	Uncharacterized protein.	Uncharacterized protein.	0.901