(11 nodes) N-Glycan biosynthesis network (Meyerozyma guilliermondii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PGUG_01153	acidPPc domain-containing protein. (228 aa)
	PGUG_02122	S5A_REDUCTASE domain-containing protein. (270 aa)
	ALG13	UDP-N-acetylglucosamine transferase subunit ALG13; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. (219 aa)
	PGUG_02581	Dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. Belongs to the DPM3 family. (92 aa)
	PGUG_02943	Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family. (86 aa)
	PGUG_03727	Uncharacterized protein. (384 aa)
	PGUG_04429	Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. (222 aa)
	PGUG_04656	Uncharacterized protein. (611 aa)
	PGUG_04668	Glycos_transf_1 domain-containing protein. (459 aa)
	PGUG_05778	Uncharacterized protein. (472 aa)
	PGUG_05788	Uncharacterized protein. (589 aa)

Your Current Organism:

Meyerozyma guilliermondii

NCBI taxonomy Id: 294746
Other names: M. guilliermondii ATCC 6260, Meyerozyma guilliermondii ATCC 6260, Pichia guilliermondii ATCC 6260

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALG13	PGUG_02581	A5DGS3	A5DH30	UDP-N-acetylglucosamine transferase subunit ALG13; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.	Dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. Belongs to the DPM3 family.	0.546
ALG13	PGUG_02943	A5DGS3	A5DI42	UDP-N-acetylglucosamine transferase subunit ALG13; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.	Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family.	0.521
ALG13	PGUG_03727	A5DGS3	A5DKC6	UDP-N-acetylglucosamine transferase subunit ALG13; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.	Uncharacterized protein.	0.993
ALG13	PGUG_04429	A5DGS3	A5DMC8	UDP-N-acetylglucosamine transferase subunit ALG13; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.	Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.	0.585
ALG13	PGUG_04668	A5DGS3	A5DN17	UDP-N-acetylglucosamine transferase subunit ALG13; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.	Glycos_transf_1 domain-containing protein.	0.980
ALG13	PGUG_05778	A5DGS3	A5DR77	UDP-N-acetylglucosamine transferase subunit ALG13; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.	Uncharacterized protein.	0.607
ALG13	PGUG_05788	A5DGS3	A5DR87	UDP-N-acetylglucosamine transferase subunit ALG13; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.	Uncharacterized protein.	0.717
PGUG_01153	PGUG_02122	A5DCZ8	A5DFS1	acidPPc domain-containing protein.	S5A_REDUCTASE domain-containing protein.	0.506
PGUG_01153	PGUG_02581	A5DCZ8	A5DH30	acidPPc domain-containing protein.	Dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. Belongs to the DPM3 family.	0.925
PGUG_01153	PGUG_02943	A5DCZ8	A5DI42	acidPPc domain-containing protein.	Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family.	0.912
PGUG_01153	PGUG_03727	A5DCZ8	A5DKC6	acidPPc domain-containing protein.	Uncharacterized protein.	0.946
PGUG_01153	PGUG_04429	A5DCZ8	A5DMC8	acidPPc domain-containing protein.	Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.	0.950
PGUG_01153	PGUG_04656	A5DCZ8	A5DN05	acidPPc domain-containing protein.	Uncharacterized protein.	0.955
PGUG_02122	PGUG_01153	A5DFS1	A5DCZ8	S5A_REDUCTASE domain-containing protein.	acidPPc domain-containing protein.	0.506
PGUG_02122	PGUG_03727	A5DFS1	A5DKC6	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein.	0.463
PGUG_02122	PGUG_04656	A5DFS1	A5DN05	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein.	0.959
PGUG_02122	PGUG_05788	A5DFS1	A5DR87	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein.	0.424
PGUG_02581	ALG13	A5DH30	A5DGS3	Dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. Belongs to the DPM3 family.	UDP-N-acetylglucosamine transferase subunit ALG13; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.	0.546
PGUG_02581	PGUG_01153	A5DH30	A5DCZ8	Dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. Belongs to the DPM3 family.	acidPPc domain-containing protein.	0.925
PGUG_02581	PGUG_02943	A5DH30	A5DI42	Dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. Belongs to the DPM3 family.	Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family.	0.995