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| | PGUG_04733 | DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. (1303 aa) |
| | PGUG_00103 | Uncharacterized protein. (269 aa) |
| | PGUG_00104 | Zn(2)-C6 fungal-type domain-containing protein. (750 aa) |
| | PGUG_00134 | BSD domain-containing protein. (620 aa) |
| | PGUG_00215 | C2H2-type domain-containing protein. (756 aa) |
| | PGUG_00243 | SAP30_Sin3_bdg domain-containing protein. (148 aa) |
| | PGUG_00259 | DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. (1144 aa) |
| | PGUG_00298 | BTP domain-containing protein. (263 aa) |
| | PGUG_00366 | Uncharacterized protein. (274 aa) |
| | PGUG_00402 | Plus3 domain-containing protein. (539 aa) |
| | PGUG_00409 | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1166 aa) |
| | PGUG_00412 | PINc domain-containing protein. (433 aa) |
| | MED4 | Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (288 aa) |
| | TAF4 | Transcription initiation factor TFIID subunit 4; Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of tra [...] (455 aa) |
| | PGUG_00438 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (123 aa) |
| | PGUG_00445 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (112 aa) |
| | PGUG_00637 | Zn(2)-C6 fungal-type domain-containing protein. (688 aa) |
| | PGUG_00670 | Protein kinase domain-containing protein. (665 aa) |
| | PGUG_00695 | Uncharacterized protein. (339 aa) |
| | PGUG_00814 | Uncharacterized protein. (305 aa) |
| | PGUG_00825 | Fungal_trans domain-containing protein. (470 aa) |
| | PGUG_00826 | Uncharacterized protein. (525 aa) |
| | PGUG_00838 | Deacetylase sirtuin-type domain-containing protein. (461 aa) |
| | PGUG_00854 | Uncharacterized protein. (440 aa) |
| | PGUG_00876 | Uncharacterized protein. (551 aa) |
| | PGUG_00968 | Uncharacterized protein. (699 aa) |
| | PGUG_01036 | Uncharacterized protein. (213 aa) |
| | PGUG_01041 | Uncharacterized protein. (1057 aa) |
| | PGUG_01067 | Zn(2)-C6 fungal-type domain-containing protein. (852 aa) |
| | PGUG_01107 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (288 aa) |
| | RPB1 | DNA-directed RNA polymerase II subunit RPB1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cl [...] (1579 aa) |
| | PGUG_01177 | Uncharacterized protein. (766 aa) |
| | PGUG_01227 | 5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (909 aa) |
| | PGUG_01245 | Uncharacterized protein. (229 aa) |
| | PGUG_01246 | ATP-dependent DNA helicase; Belongs to the helicase family. (426 aa) |
| | BYE1 | Transcription factor BYE1; Negative regulator of transcription elongation. Belongs to the BYE1 family. (752 aa) |
| | PGUG_01279 | Uncharacterized protein. (495 aa) |
| | PGUG_01300 | TAF domain-containing protein. (489 aa) |
| | PGUG_01313 | TFIID_20kDa domain-containing protein. (515 aa) |
| | PGUG_01395 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (111 aa) |
| | PGUG_01460 | RPOL4c domain-containing protein. (188 aa) |
| | PGUG_01477 | Uncharacterized protein. (1895 aa) |
| | PGUG_01478 | Uncharacterized protein. (223 aa) |
| | PGUG_01485 | Uncharacterized protein. (566 aa) |
| | PGUG_01639 | Zn(2)-C6 fungal-type domain-containing protein. (632 aa) |
| | RTT106 | Histone chaperone RTT106; Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing. Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by creating a repressive structure at the core histone gene promoter (By similarity). (443 aa) |
| | PGUG_01742 | Zn(2)-C6 fungal-type domain-containing protein. (994 aa) |
| | PGUG_01753 | PCI domain-containing protein. (464 aa) |
| | PGUG_01774 | Uncharacterized protein. (239 aa) |
| | PGUG_01783 | Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (269 aa) |
| | PGUG_01872 | DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (148 aa) |
| | PGUG_01880 | Uncharacterized protein. (952 aa) |
| | PGUG_01933 | Uncharacterized protein. (334 aa) |
| | HHT1 | Histone H3.1/H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (136 aa) |
| | PGUG_02014 | Uncharacterized protein. (288 aa) |
| | PGUG_02050 | DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (306 aa) |
| | PGUG_02059 | Uncharacterized protein. (1601 aa) |
| | PGUG_02079 | Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (786 aa) |
| | PGUG_02088 | Uncharacterized protein. (380 aa) |
| | PGUG_02149 | UvrD-like helicase ATP-binding domain-containing protein. (1359 aa) |
| | PGUG_02177 | Response regulatory domain-containing protein. (491 aa) |
| | PGUG_02223 | TAF8_C domain-containing protein. (529 aa) |
| | HHT3 | Histone H3.3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (136 aa) |
| | SUS1 | Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex required for deubiquitination of [...] (97 aa) |
| | PGUG_02265 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (507 aa) |
| | PGUG_02338 | RNB domain-containing protein; Belongs to the RNR ribonuclease family. (1095 aa) |
| | PGUG_02347 | Fungal_trans domain-containing protein. (353 aa) |
| | PGUG_02408 | Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (532 aa) |
| | PGUG_02412 | Uncharacterized protein. (242 aa) |
| | PGUG_02475 | Uncharacterized protein. (186 aa) |
| | PGUG_02478 | TAFII55_N domain-containing protein. (501 aa) |
| | PGUG_02490 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (331 aa) |
| | PGUG_02509 | Zn(2)-C6 fungal-type domain-containing protein. (712 aa) |
| | PGUG_02580 | Uncharacterized protein. (542 aa) |
| | PIF1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (722 aa) |
| | PGUG_02671 | Uncharacterized protein. (146 aa) |
| | PGUG_02685 | Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1028 aa) |
| | PGUG_02686 | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (242 aa) |
| | PGUG_02741 | Uncharacterized protein; Belongs to the RNR ribonuclease family. (978 aa) |
| | PGUG_02765 | DNA-directed RNA polymerases II 24 kDa polypeptide. (179 aa) |
| | PGUG_02831 | Uncharacterized protein. (173 aa) |
| | RPB2 | DNA-directed RNA polymerase II subunit RPB2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB2 is [...] (1236 aa) |
| | PGUG_02891 | Uncharacterized protein. (216 aa) |
| | PGUG_02958 | Uncharacterized protein. (326 aa) |
| | PGUG_02992 | CBFD_NFYB_HMF domain-containing protein. (137 aa) |
| | PGUG_03001 | Uncharacterized protein. (282 aa) |
| | PGUG_03007 | RRN7-type domain-containing protein. (502 aa) |
| | PGUG_03017 | RPOL4c domain-containing protein. (148 aa) |
| | PGUG_03019 | Fungal_trans domain-containing protein. (505 aa) |
| | PGUG_03020 | Zn(2)-C6 fungal-type domain-containing protein. (229 aa) |
| | PGUG_03110 | Uncharacterized protein. (1056 aa) |
| | PGUG_03132 | CENP-T_C domain-containing protein. (646 aa) |
| | PGUG_03166 | Zn(2)-C6 fungal-type domain-containing protein. (819 aa) |
| | PGUG_03204 | CBFD_NFYB_HMF domain-containing protein. (140 aa) |
| | PGUG_03240 | Zn(2)-C6 fungal-type domain-containing protein. (858 aa) |
| | PGUG_03263 | Fungal_trans domain-containing protein. (245 aa) |
| | PGUG_03272 | Zn(2)-C6 fungal-type domain-containing protein. (691 aa) |
| | PGUG_03281 | Uncharacterized protein. (819 aa) |
| | PGUG_03287 | Uncharacterized protein; Belongs to the DapA family. (319 aa) |
| | PGUG_03295 | Uncharacterized protein. (443 aa) |
| | PGUG_03296 | Zn(2)-C6 fungal-type domain-containing protein. (356 aa) |
| | PGUG_03382 | Uncharacterized protein. (706 aa) |
| | PGUG_03390 | Zn(2)-C6 fungal-type domain-containing protein. (828 aa) |
| | PGUG_03391 | Zn(2)-C6 fungal-type domain-containing protein. (820 aa) |
| | PGUG_03419 | Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (116 aa) |
| | PGUG_03590 | Uncharacterized protein; Belongs to the DapA family. (302 aa) |
| | PGUG_03593 | Bac_rhamnosid6H domain-containing protein. (552 aa) |
| | PGUG_03608 | HTH TFE/IIEalpha-type domain-containing protein. (380 aa) |
| | PGUG_03660 | CID domain-containing protein. (427 aa) |
| | PGUG_03683 | Uncharacterized protein. (442 aa) |
| | PGUG_03709 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1632 aa) |
| | PGUG_03711 | Uncharacterized protein. (514 aa) |
| | PGUG_03851 | HTH myb-type domain-containing protein. (710 aa) |
| | PGUG_03882 | SANT domain-containing protein. (586 aa) |
| | PGUG_03893 | Zn(2)-C6 fungal-type domain-containing protein. (636 aa) |
| | PGUG_03905 | Isochorismatase domain-containing protein. (188 aa) |
| | PGUG_03938 | Zn(2)-C6 fungal-type domain-containing protein. (724 aa) |
| | PGUG_04028 | Zn(2)-C6 fungal-type domain-containing protein. (789 aa) |
| | PGUG_04032 | RNA_pol_L_2 domain-containing protein. (123 aa) |
| | PGUG_04052 | Uncharacterized protein. (72 aa) |
| | PGUG_04087 | HMG box domain-containing protein. (317 aa) |
| | PGUG_04089 | GATA-type domain-containing protein. (539 aa) |
| | PGUG_04096 | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1156 aa) |
| | PGUG_04106 | Uncharacterized protein. (356 aa) |
| | PGUG_04116 | Zn(2)-C6 fungal-type domain-containing protein. (794 aa) |
| | PGUG_04275 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (754 aa) |
| | PGUG_04298 | TATA-box binding protein. (240 aa) |
| | PGUG_04303 | Helicase ATP-binding domain-containing protein. (843 aa) |
| | PGUG_04305 | Uncharacterized protein. (373 aa) |
| | PGUG_04328 | Zn(2)-C6 fungal-type domain-containing protein. (870 aa) |
| | PGUG_04329 | Zn(2)-C6 fungal-type domain-containing protein. (694 aa) |
| | PGUG_04343 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1379 aa) |
| | PGUG_04415 | Uncharacterized protein. (192 aa) |
| | PGUG_04416 | Uncharacterized protein. (320 aa) |
| | PGUG_04445 | Uncharacterized protein. (371 aa) |
| | PGUG_04488 | Zn(2)-C6 fungal-type domain-containing protein. (251 aa) |
| | PGUG_04489 | Fungal_trans domain-containing protein. (436 aa) |
| | PGUG_04502 | Zn(2)-C6 fungal-type domain-containing protein. (834 aa) |
| | PGUG_04507 | Zn(2)-C6 fungal-type domain-containing protein. (560 aa) |
| | PGUG_04509 | Uncharacterized protein. (606 aa) |
| | PGUG_04565 | Fungal_trans domain-containing protein. (352 aa) |
| | PGUG_04646 | Uncharacterized protein. (757 aa) |
| | PGUG_04749 | CDC73_C domain-containing protein. (373 aa) |
| | PGUG_04809 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | PGUG_04829 | Uncharacterized protein. (761 aa) |
| | PGUG_04847 | Zn(2)-C6 fungal-type domain-containing protein. (156 aa) |
| | PGUG_04848 | Fungal_trans domain-containing protein. (599 aa) |
| | PGUG_04924 | Uncharacterized protein. (650 aa) |
| | PGUG_04942 | General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (488 aa) |
| | PGUG_04964 | TFIIIC_delta domain-containing protein. (746 aa) |
| | PGUG_04989 | Uncharacterized protein. (73 aa) |
| | PGUG_05071 | Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (211 aa) |
| | PGUG_05130 | Nuclear cap-binding protein subunit 2. (198 aa) |
| | PGUG_05131 | Uncharacterized protein. (325 aa) |
| | PGUG_05134 | Uncharacterized protein. (415 aa) |
| | PGUG_05141 | Zn(2)-C6 fungal-type domain-containing protein. (689 aa) |
| | PGUG_05155 | Zn(2)-C6 fungal-type domain-containing protein. (637 aa) |
| | PGUG_05171 | Uncharacterized protein. (373 aa) |
| | PGUG_05192 | Uncharacterized protein. (778 aa) |
| | PGUG_05205 | Fungal_trans domain-containing protein. (544 aa) |
| | PGUG_05214 | Uncharacterized protein. (561 aa) |
| | PGUG_05248 | Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (123 aa) |
| | PGUG_05271 | rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (385 aa) |
| | PGUG_05290 | eRF1_1 domain-containing protein. (435 aa) |
| | PGUG_05311 | Protein kinase domain-containing protein. (554 aa) |
| | PGUG_05316 | RPOLD domain-containing protein. (333 aa) |
| | PGUG_05318 | U3 small nucleolar RNA-associated protein 22. (1161 aa) |
| | PGUG_05349 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (330 aa) |
| | PGUG_05357 | Uncharacterized protein. (405 aa) |
| | PGUG_05384 | Zn(2)-C6 fungal-type domain-containing protein. (674 aa) |
| | PGUG_05395 | RPOLD domain-containing protein. (305 aa) |
| | PGUG_05425 | Uncharacterized protein. (158 aa) |
| | PGUG_05450 | Uncharacterized protein. (840 aa) |
| | RPC82 | DNA-directed RNA polymerase III subunit RPC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (By similarity). (588 aa) |
| | PGUG_05526 | Uncharacterized protein. (194 aa) |
| | PGUG_05580 | TAFII28 domain-containing protein. (241 aa) |
| | PGUG_05648 | Uncharacterized protein. (410 aa) |
| | PGUG_05654 | BHLH domain-containing protein. (223 aa) |
| | PGUG_05740 | SWIB domain-containing protein. (185 aa) |
| | PGUG_05851 | Uncharacterized protein. (69 aa) |
| | PGUG_05877 | B-block_TFIIIC domain-containing protein. (1171 aa) |
