STRINGSTRING
PGUG_01783 PGUG_01783 PGUG_01460 PGUG_01460 PGUG_01313 PGUG_01313 PGUG_02992 PGUG_02992 PGUG_03007 PGUG_03007 PGUG_03017 PGUG_03017 PGUG_03110 PGUG_03110 PGUG_03132 PGUG_03132 PGUG_03204 PGUG_03204 PGUG_03240 PGUG_03240 PGUG_03608 PGUG_03608 PGUG_03882 PGUG_03882 PGUG_05877 PGUG_05877 PGUG_04303 PGUG_04303 PGUG_05851 PGUG_05851 PGUG_05740 PGUG_05740 PGUG_05648 PGUG_05648 PGUG_05580 PGUG_05580 PGUG_04298 PGUG_04298 PGUG_04089 PGUG_04089 PGUG_04087 PGUG_04087 PGUG_04032 PGUG_04032 PGUG_01300 PGUG_01300 PGUG_01036 PGUG_01036 PGUG_00968 PGUG_00968 PGUG_00814 PGUG_00814 PGUG_00695 PGUG_00695 PGUG_00445 PGUG_00445 TAF4 TAF4 MED4 MED4 PGUG_00409 PGUG_00409 PGUG_05450 PGUG_05450 PGUG_05425 PGUG_05425 PGUG_05271 PGUG_05271 PGUG_05248 PGUG_05248 PGUG_05071 PGUG_05071 PGUG_03938 PGUG_03938 PGUG_04989 PGUG_04989 PGUG_05526 PGUG_05526 PGUG_04964 PGUG_04964 PGUG_04924 PGUG_04924 PGUG_04809 PGUG_04809 PGUG_04733 PGUG_04733 PGUG_02831 PGUG_02831 PGUG_02671 PGUG_02671 PGUG_02580 PGUG_02580 PGUG_02490 PGUG_02490 PGUG_02478 PGUG_02478 PGUG_02475 PGUG_02475 PGUG_02408 PGUG_02408 PGUG_02223 PGUG_02223 PGUG_02088 PGUG_02088 PGUG_02059 PGUG_02059 PGUG_01933 PGUG_01933
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PGUG_01783Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (269 aa)
PGUG_01460RPOL4c domain-containing protein. (188 aa)
PGUG_01313TFIID_20kDa domain-containing protein. (515 aa)
PGUG_02992CBFD_NFYB_HMF domain-containing protein. (137 aa)
PGUG_03007RRN7-type domain-containing protein. (502 aa)
PGUG_03017RPOL4c domain-containing protein. (148 aa)
PGUG_03110Uncharacterized protein. (1056 aa)
PGUG_03132CENP-T_C domain-containing protein. (646 aa)
PGUG_03204CBFD_NFYB_HMF domain-containing protein. (140 aa)
PGUG_03240Zn(2)-C6 fungal-type domain-containing protein. (858 aa)
PGUG_03608HTH TFE/IIEalpha-type domain-containing protein. (380 aa)
PGUG_03882SANT domain-containing protein. (586 aa)
PGUG_05877B-block_TFIIIC domain-containing protein. (1171 aa)
PGUG_04303Helicase ATP-binding domain-containing protein. (843 aa)
PGUG_05851Uncharacterized protein. (69 aa)
PGUG_05740SWIB domain-containing protein. (185 aa)
PGUG_05648Uncharacterized protein. (410 aa)
PGUG_05580TAFII28 domain-containing protein. (241 aa)
PGUG_04298TATA-box binding protein. (240 aa)
PGUG_04089GATA-type domain-containing protein. (539 aa)
PGUG_04087HMG box domain-containing protein. (317 aa)
PGUG_04032RNA_pol_L_2 domain-containing protein. (123 aa)
PGUG_01300TAF domain-containing protein. (489 aa)
PGUG_01036Uncharacterized protein. (213 aa)
PGUG_00968Uncharacterized protein. (699 aa)
PGUG_00814Uncharacterized protein. (305 aa)
PGUG_00695Uncharacterized protein. (339 aa)
PGUG_00445DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (112 aa)
TAF4Transcription initiation factor TFIID subunit 4; Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of tra [...] (455 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (288 aa)
PGUG_00409DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1166 aa)
PGUG_05450Uncharacterized protein. (840 aa)
PGUG_05425Uncharacterized protein. (158 aa)
PGUG_05271rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (385 aa)
PGUG_05248Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (123 aa)
PGUG_05071Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (211 aa)
PGUG_03938Zn(2)-C6 fungal-type domain-containing protein. (724 aa)
PGUG_04989Uncharacterized protein. (73 aa)
PGUG_05526Uncharacterized protein. (194 aa)
PGUG_04964TFIIIC_delta domain-containing protein. (746 aa)
PGUG_04924Uncharacterized protein. (650 aa)
PGUG_04809Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
PGUG_04733DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. (1303 aa)
PGUG_02831Uncharacterized protein. (173 aa)
PGUG_02671Uncharacterized protein. (146 aa)
PGUG_02580Uncharacterized protein. (542 aa)
PGUG_02490Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (331 aa)
PGUG_02478TAFII55_N domain-containing protein. (501 aa)
PGUG_02475Uncharacterized protein. (186 aa)
PGUG_02408Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (532 aa)
PGUG_02223TAF8_C domain-containing protein. (529 aa)
PGUG_02088Uncharacterized protein. (380 aa)
PGUG_02059Uncharacterized protein. (1601 aa)
PGUG_01933Uncharacterized protein. (334 aa)
Your Current Organism:
Meyerozyma guilliermondii
NCBI taxonomy Id: 294746
Other names: M. guilliermondii ATCC 6260, Meyerozyma guilliermondii ATCC 6260, Pichia guilliermondii ATCC 6260
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