28 items (Meyerozyma guilliermondii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PGUG_04989	Uncharacterized protein. (73 aa)
	PGUG_04749	CDC73_C domain-containing protein. (373 aa)
	PGUG_04305	Uncharacterized protein. (373 aa)
	PGUG_04275	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (754 aa)
	PGUG_04032	RNA_pol_L_2 domain-containing protein. (123 aa)
	PGUG_03419	Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (116 aa)
	PGUG_02088	Uncharacterized protein. (380 aa)
	PGUG_02685	Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1028 aa)
	PGUG_02177	Response regulatory domain-containing protein. (491 aa)
	SUS1	Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex required for deubiquitination of [...] (97 aa)
	PGUG_02265	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (507 aa)
	PGUG_04445	Uncharacterized protein. (371 aa)
	PGUG_00402	Plus3 domain-containing protein. (539 aa)
	PGUG_00409	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1166 aa)
	PGUG_00412	PINc domain-containing protein. (433 aa)
	PGUG_00445	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (112 aa)
	PGUG_00670	Protein kinase domain-containing protein. (665 aa)
	PGUG_00854	Uncharacterized protein. (440 aa)
	PGUG_01036	Uncharacterized protein. (213 aa)
	PGUG_01460	RPOL4c domain-containing protein. (188 aa)
	RTT106	Histone chaperone RTT106; Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing. Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by creating a repressive structure at the core histone gene promoter (By similarity). (443 aa)
	PGUG_01753	PCI domain-containing protein. (464 aa)
	PGUG_02014	Uncharacterized protein. (288 aa)
	PGUG_05654	BHLH domain-containing protein. (223 aa)
	PGUG_05648	Uncharacterized protein. (410 aa)
	PGUG_05425	Uncharacterized protein. (158 aa)
	PGUG_05311	Protein kinase domain-containing protein. (554 aa)
	PGUG_05134	Uncharacterized protein. (415 aa)

Your Current Organism:

Meyerozyma guilliermondii

NCBI taxonomy Id: 294746
Other names: M. guilliermondii ATCC 6260, Meyerozyma guilliermondii ATCC 6260, Pichia guilliermondii ATCC 6260

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PGUG_00402	PGUG_00409	A5DAU7	A5DAV4	Plus3 domain-containing protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.660
PGUG_00402	PGUG_00445	A5DAU7	A5DAZ0	Plus3 domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.830
PGUG_00402	PGUG_01036	A5DAU7	A5DCN1	Plus3 domain-containing protein.	Uncharacterized protein.	0.792
PGUG_00402	PGUG_01460	A5DAU7	A5DDV9	Plus3 domain-containing protein.	RPOL4c domain-containing protein.	0.853
PGUG_00402	PGUG_03419	A5DAU7	A5DJG8	Plus3 domain-containing protein.	Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family.	0.575
PGUG_00402	PGUG_04305	A5DAU7	A5DM04	Plus3 domain-containing protein.	Uncharacterized protein.	0.996
PGUG_00402	PGUG_04749	A5DAU7	A5DN98	Plus3 domain-containing protein.	CDC73_C domain-containing protein.	0.998
PGUG_00402	PGUG_04989	A5DAU7	A5DNY8	Plus3 domain-containing protein.	Uncharacterized protein.	0.830
PGUG_00402	PGUG_05134	A5DAU7	A5DPD3	Plus3 domain-containing protein.	Uncharacterized protein.	0.996
PGUG_00402	PGUG_05425	A5DAU7	A5DQ74	Plus3 domain-containing protein.	Uncharacterized protein.	0.806
PGUG_00409	PGUG_00402	A5DAV4	A5DAU7	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Plus3 domain-containing protein.	0.660
PGUG_00409	PGUG_00445	A5DAV4	A5DAZ0	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.721
PGUG_00409	PGUG_01036	A5DAV4	A5DCN1	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.557
PGUG_00409	PGUG_01460	A5DAV4	A5DDV9	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RPOL4c domain-containing protein.	0.913
PGUG_00409	PGUG_02014	A5DAV4	A5DFG3	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.579
PGUG_00409	PGUG_02088	A5DAV4	A5DFN7	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.878
PGUG_00409	PGUG_03419	A5DAV4	A5DJG8	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family.	0.642
PGUG_00409	PGUG_04032	A5DAV4	A5DL81	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA_pol_L_2 domain-containing protein.	0.996
PGUG_00409	PGUG_04305	A5DAV4	A5DM04	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.647
PGUG_00409	PGUG_04749	A5DAV4	A5DN98	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	CDC73_C domain-containing protein.	0.695