(104 nodes) Site of polarized growth network (Meyerozyma guilliermondii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PGUG_02535	Uncharacterized protein. (326 aa)
	PGUG_00177	Uncharacterized protein. (1352 aa)
	PGUG_00200	Chitin synthase; Plays a major role in cell wall biogenesis. (779 aa)
	PGUG_00201	Uncharacterized protein. (166 aa)
	PGUG_00273	SH3 domain-containing protein. (591 aa)
	PGUG_00317	Uncharacterized protein. (952 aa)
	PGUG_00333	Adenylyl cyclase-associated protein; Belongs to the CAP family. (601 aa)
	PGUG_00435	Uncharacterized protein; Belongs to the actin family. (454 aa)
	PGUG_00489	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (682 aa)
	PGUG_00557	Uncharacterized protein. (302 aa)
	PGUG_00573	Glycosidase; Belongs to the glycosyl hydrolase 16 family. (452 aa)
	PGUG_00625	Sec3-PIP2_bind domain-containing protein. (1301 aa)
	PGUG_00774	Uncharacterized protein. (159 aa)
	PGUG_00872	Uncharacterized protein. (146 aa)
	PGUG_00909	Uncharacterized protein. (247 aa)
	PGUG_00913	Uncharacterized protein. (740 aa)
	PGUG_00954	Uncharacterized protein. (841 aa)
	PGUG_01022	Protein kinase domain-containing protein. (725 aa)
	PGUG_01072	PH domain-containing protein. (1458 aa)
	PGUG_01144	Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (399 aa)
	PGUG_01151	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (426 aa)
	PGUG_01321	Uncharacterized protein. (615 aa)
	PGUG_01437	Uncharacterized protein. (205 aa)
	PGUG_01535	MHD domain-containing protein. (927 aa)
	PGUG_01547	Exocyst complex protein EXO70; Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Also plays a role in the assembly of the exocyst. Belongs to the EXO70 family. (602 aa)
	PGUG_01556	E3 ubiquitin-protein ligase. (773 aa)
	PGUG_01623	Uncharacterized protein. (1455 aa)
	PGUG_01628	Uncharacterized protein. (600 aa)
	PGUG_01686	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (407 aa)
	PGUG_01828	MARVEL domain-containing protein. (170 aa)
	PGUG_01845	Mso1_Sec1_bdg domain-containing protein. (220 aa)
	PGUG_02017	Uncharacterized protein. (1037 aa)
	PGUG_02032	Uncharacterized protein. (2325 aa)
	PGUG_02033	Uncharacterized protein. (245 aa)
	PGUG_02067	Uncharacterized protein. (275 aa)
	PGUG_02145	Uncharacterized protein. (1317 aa)
	PGUG_02379	Uncharacterized protein. (201 aa)
	PGUG_02391	Uncharacterized protein. (680 aa)
	PGUG_02457	Uncharacterized protein. (337 aa)
	PGUG_02494	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1633 aa)
	PGUG_02637	Uncharacterized protein. (416 aa)
	PGUG_02644	WH1 domain-containing protein. (554 aa)
	PGUG_02721	Uncharacterized protein. (355 aa)
	PGUG_02774	BAR domain-containing protein. (258 aa)
	PGUG_02814	PRMT5 domain-containing protein. (447 aa)
	PGUG_03009	Uncharacterized protein. (840 aa)
	PGUG_03224	Uncharacterized protein. (1184 aa)
	PGUG_03234	Uncharacterized protein. (1325 aa)
	PGUG_03305	Protein kinase domain-containing protein. (1280 aa)
	PRM1	Plasma membrane fusion protein PRM1; Involved in cell fusion during mating by stabilizing the plasma membrane fusion event; Belongs to the PRM1 family. (630 aa)
	PGUG_03316	PH domain-containing protein. (1032 aa)
	PGUG_03346	Uncharacterized protein. (500 aa)
	PGUG_03379	Uncharacterized protein. (718 aa)
	PGUG_03411	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1951 aa)
	PGUG_03452	PIPK domain-containing protein. (612 aa)
	PGUG_03483	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
	PGUG_03628	Sec2p domain-containing protein. (631 aa)
	PGUG_03629	Uncharacterized protein. (1711 aa)
	PGUG_03643	Uncharacterized protein. (1153 aa)
	PGUG_03656	Uncharacterized protein. (431 aa)
	PGUG_03703	Uncharacterized protein. (1208 aa)
	PGUG_03792	Exo84_C domain-containing protein. (744 aa)
	PGUG_03801	TYR_PHOSPHATASE_2 domain-containing protein. (453 aa)
	PGUG_03812	Sec8_exocyst domain-containing protein. (1095 aa)
	PGUG_03840	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (484 aa)
	PGUG_03860	Uncharacterized protein. (258 aa)
	PGUG_04000	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (730 aa)
	PGUG_04046	Hist_deacetyl domain-containing protein. (686 aa)
	PGUG_04047	Uncharacterized protein. (883 aa)
	PGUG_04122	Uncharacterized protein. (218 aa)
	PGUG_04130	Non-specific serine/threonine protein kinase. (576 aa)
	PGUG_04163	Protein kinase domain-containing protein. (575 aa)
	PGUG_04226	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (327 aa)
	PGUG_04231	Uncharacterized protein. (1162 aa)
	PGUG_04274	Uncharacterized protein. (284 aa)
	PGUG_04276	Serine/threonine-protein kinase. (646 aa)
	PGUG_04279	DUF3507 domain-containing protein. (1178 aa)
	PGUG_04300	BAR domain-containing protein. (264 aa)
	PGUG_04307	Uncharacterized protein. (501 aa)
	PGUG_04327	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (396 aa)
	PGUG_04372	UDENN domain-containing protein. (649 aa)
	PGUG_04383	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1047 aa)
	PGUG_04386	Protein kinase domain-containing protein. (1410 aa)
	PGUG_04396	Cell division control protein 42. (191 aa)
	PGUG_04431	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)
	PGUG_04446	Uncharacterized protein. (507 aa)
	PGUG_04521	Exocyst complex component SEC15; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (859 aa)
	PGUG_04665	Calmodulin; Belongs to the calmodulin family. (113 aa)
	PGUG_04690	Uncharacterized protein. (1548 aa)
	PGUG_04691	WD_REPEATS_REGION domain-containing protein. (443 aa)
	PGUG_04732	Uncharacterized protein. (289 aa)
	PGUG_04785	Cell division control protein 28. (307 aa)
	PGUG_04880	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (744 aa)
	PGUG_05012	SEC7 domain-containing protein. (887 aa)
	PGUG_05112	Protein kinase domain-containing protein. (952 aa)
	PGUG_05229	Uncharacterized protein. (1143 aa)
	PGUG_05263	Uncharacterized protein. (418 aa)
	PGUG_05266	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (406 aa)
	PGUG_05433	C2 domain-containing protein. (530 aa)
	PGUG_05711	Uncharacterized protein. (1157 aa)
	PGUG_05773	Casein kinase I isoform delta; Belongs to the protein kinase superfamily. (430 aa)
	PGUG_05827	Glutaredoxin domain-containing protein. (790 aa)
	PGUG_05835	Uncharacterized protein. (1190 aa)
	PGUG_05882	AIP3 domain-containing protein. (678 aa)

Your Current Organism:

Meyerozyma guilliermondii

NCBI taxonomy Id: 294746
Other names: M. guilliermondii ATCC 6260, Meyerozyma guilliermondii ATCC 6260, Pichia guilliermondii ATCC 6260

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PGUG_00200	PGUG_00201	A5DA95	A5DA96	Chitin synthase; Plays a major role in cell wall biogenesis.	Uncharacterized protein.	0.608
PGUG_00200	PGUG_02017	A5DA95	A5DFG6	Chitin synthase; Plays a major role in cell wall biogenesis.	Uncharacterized protein.	0.568
PGUG_00200	PGUG_04276	A5DA95	A5DLX5	Chitin synthase; Plays a major role in cell wall biogenesis.	Serine/threonine-protein kinase.	0.502
PGUG_00201	PGUG_00200	A5DA96	A5DA95	Uncharacterized protein.	Chitin synthase; Plays a major role in cell wall biogenesis.	0.608
PGUG_00201	PGUG_02017	A5DA96	A5DFG6	Uncharacterized protein.	Uncharacterized protein.	0.568
PGUG_00201	PGUG_04276	A5DA96	A5DLX5	Uncharacterized protein.	Serine/threonine-protein kinase.	0.502
PGUG_00273	PGUG_02391	A5DAG8	A5DGJ0	SH3 domain-containing protein.	Uncharacterized protein.	0.536
PGUG_00273	PGUG_02644	A5DAG8	A5DH93	SH3 domain-containing protein.	WH1 domain-containing protein.	0.583
PGUG_00273	PGUG_02774	A5DAG8	A5DHM3	SH3 domain-containing protein.	BAR domain-containing protein.	0.818
PGUG_00273	PGUG_03379	A5DAG8	A5DJC8	SH3 domain-containing protein.	Uncharacterized protein.	0.515
PGUG_00273	PGUG_04300	A5DAG8	A5DLZ9	SH3 domain-containing protein.	BAR domain-containing protein.	0.627
PGUG_00273	PGUG_04307	A5DAG8	A5DM06	SH3 domain-containing protein.	Uncharacterized protein.	0.531
PGUG_00333	PGUG_00435	A5DAM8	A5DAY0	Adenylyl cyclase-associated protein; Belongs to the CAP family.	Uncharacterized protein; Belongs to the actin family.	0.628
PGUG_00333	PGUG_02017	A5DAM8	A5DFG6	Adenylyl cyclase-associated protein; Belongs to the CAP family.	Uncharacterized protein.	0.548
PGUG_00333	PGUG_02391	A5DAM8	A5DGJ0	Adenylyl cyclase-associated protein; Belongs to the CAP family.	Uncharacterized protein.	0.971
PGUG_00333	PGUG_03703	A5DAM8	A5DKA2	Adenylyl cyclase-associated protein; Belongs to the CAP family.	Uncharacterized protein.	0.548
PGUG_00333	PGUG_04431	A5DAM8	A5DMD0	Adenylyl cyclase-associated protein; Belongs to the CAP family.	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	0.871
PGUG_00435	PGUG_00333	A5DAY0	A5DAM8	Uncharacterized protein; Belongs to the actin family.	Adenylyl cyclase-associated protein; Belongs to the CAP family.	0.628
PGUG_00435	PGUG_00557	A5DAY0	A5DBA2	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein.	0.414
PGUG_00435	PGUG_02017	A5DAY0	A5DFG6	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein.	0.630