(11 nodes) Site of double-strand break network (Meyerozyma guilliermondii)

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second shell of interactors

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proteins of unknown 3D structure

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Predicted Interactions

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Your Input:
	PGUG_00490	Uncharacterized protein. (1154 aa)
	PGUG_05238	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (311 aa)
	PGUG_04361	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (616 aa)
	PGUG_04191	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (641 aa)
	PGUG_03869	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (333 aa)
	PGUG_03630	Uncharacterized protein. (1278 aa)
	PGUG_02273	Uncharacterized protein. (293 aa)
	PGUG_00161	AAA_23 domain-containing protein. (1082 aa)
	PGUG_00279	DUF2439 domain-containing protein. (200 aa)
	PGUG_00452	RPA_C domain-containing protein. (251 aa)
	PGUG_01511	UmuC domain-containing protein. (673 aa)

Your Current Organism:

Meyerozyma guilliermondii

NCBI taxonomy Id: 294746
Other names: M. guilliermondii ATCC 6260, Meyerozyma guilliermondii ATCC 6260, Pichia guilliermondii ATCC 6260

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PGUG_00161	PGUG_03869	A5DA56	A5DKR8	AAA_23 domain-containing protein.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.682
PGUG_00161	PGUG_04361	A5DA56	A5DM60	AAA_23 domain-containing protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.635
PGUG_00452	PGUG_01511	A5DAZ7	A5DE10	RPA_C domain-containing protein.	UmuC domain-containing protein.	0.683
PGUG_00452	PGUG_02273	A5DAZ7	A5DG72	RPA_C domain-containing protein.	Uncharacterized protein.	0.684
PGUG_00452	PGUG_03869	A5DAZ7	A5DKR8	RPA_C domain-containing protein.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.839
PGUG_00452	PGUG_04191	A5DAZ7	A5DLP0	RPA_C domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.740
PGUG_00452	PGUG_04361	A5DAZ7	A5DM60	RPA_C domain-containing protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.876
PGUG_00452	PGUG_05238	A5DAZ7	A5DPN7	RPA_C domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.940
PGUG_01511	PGUG_00452	A5DE10	A5DAZ7	UmuC domain-containing protein.	RPA_C domain-containing protein.	0.683
PGUG_01511	PGUG_03869	A5DE10	A5DKR8	UmuC domain-containing protein.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.774
PGUG_01511	PGUG_04191	A5DE10	A5DLP0	UmuC domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.528
PGUG_01511	PGUG_04361	A5DE10	A5DM60	UmuC domain-containing protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.534
PGUG_01511	PGUG_05238	A5DE10	A5DPN7	UmuC domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.997
PGUG_02273	PGUG_00452	A5DG72	A5DAZ7	Uncharacterized protein.	RPA_C domain-containing protein.	0.684
PGUG_02273	PGUG_03869	A5DG72	A5DKR8	Uncharacterized protein.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.630
PGUG_02273	PGUG_04191	A5DG72	A5DLP0	Uncharacterized protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.774
PGUG_02273	PGUG_04361	A5DG72	A5DM60	Uncharacterized protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.556
PGUG_03869	PGUG_00161	A5DKR8	A5DA56	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	AAA_23 domain-containing protein.	0.682
PGUG_03869	PGUG_00452	A5DKR8	A5DAZ7	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	RPA_C domain-containing protein.	0.839
PGUG_03869	PGUG_01511	A5DKR8	A5DE10	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	UmuC domain-containing protein.	0.774