STRINGSTRING
PGUG_02757 PGUG_02757 RIB1 RIB1 PGUG_05873 PGUG_05873 PGUG_05840 PGUG_05840 COQ6 COQ6 PGUG_05631 PGUG_05631 PGUG_05628 PGUG_05628 PGUG_05611 PGUG_05611 PGUG_05560 PGUG_05560 PGUG_05559 PGUG_05559 PGUG_05558 PGUG_05558 PGUG_05557 PGUG_05557 PGUG_05535 PGUG_05535 MCR1 MCR1 PGUG_05447 PGUG_05447 PGUG_05396 PGUG_05396 PGUG_05380 PGUG_05380 PGUG_05378 PGUG_05378 PGUG_05365 PGUG_05365 BNA4 BNA4 PGUG_05322 PGUG_05322 PGUG_05319 PGUG_05319 PGUG_05303 PGUG_05303 PGUG_05302 PGUG_05302 PGUG_05253 PGUG_05253 PGUG_05252 PGUG_05252 PGUG_05240 PGUG_05240 PGUG_02708 PGUG_02708 PGUG_02684 PGUG_02684 PGUG_02670 PGUG_02670 PGUG_02623 PGUG_02623 PGUG_02619 PGUG_02619 PGUG_02603 PGUG_02603 PGUG_02590 PGUG_02590 PGUG_02577 PGUG_02577 PGUG_02562 PGUG_02562 PGUG_02536 PGUG_02536 PGUG_02506 PGUG_02506 PGUG_02477 PGUG_02477 PGUG_02458 PGUG_02458 PGUG_02417 PGUG_02417 PGUG_02404 PGUG_02404 PGUG_02402 PGUG_02402 PGUG_02400 PGUG_02400 PGUG_02382 PGUG_02382 PGUG_02360 PGUG_02360 ADI1 ADI1 PGUG_02272 PGUG_02272 PGUG_02270 PGUG_02270 PGUG_02249 PGUG_02249 PGUG_02240 PGUG_02240 PGUG_02229 PGUG_02229 PGUG_02219 PGUG_02219 PGUG_02209 PGUG_02209 PGUG_02174 PGUG_02174 PGUG_02173 PGUG_02173 PGUG_02125 PGUG_02125 PGUG_02122 PGUG_02122 PGUG_02118 PGUG_02118 PGUG_02105 PGUG_02105 PGUG_02101 PGUG_02101 PGUG_02078 PGUG_02078 PGUG_02075 PGUG_02075 PGUG_02052 PGUG_02052 PGUG_02024 PGUG_02024 PGUG_02009 PGUG_02009 PGUG_01980 PGUG_01980 PGUG_01908 PGUG_01908 PGUG_01897 PGUG_01897 ERT1 ERT1 PGUG_01843 PGUG_01843 PGUG_01831 PGUG_01831 PGUG_01824 PGUG_01824 PGUG_01797 PGUG_01797 PGUG_01763 PGUG_01763 PGUG_01720 PGUG_01720 PGUG_01716 PGUG_01716 PGUG_01677 PGUG_01677 PGUG_01645 PGUG_01645 PGUG_01631 PGUG_01631 PGUG_01629 PGUG_01629 PGUG_01529 PGUG_01529 PGUG_01505 PGUG_01505 PGUG_01501 PGUG_01501 PGUG_01496 PGUG_01496 PGUG_01489 PGUG_01489 PGUG_01480 PGUG_01480 PGUG_01467 PGUG_01467 PGUG_01426 PGUG_01426 PGUG_01424 PGUG_01424 PGUG_01420 PGUG_01420 PGUG_01405 PGUG_01405 PGUG_01382 PGUG_01382 PGUG_01379 PGUG_01379 PGUG_01375 PGUG_01375 PGUG_01364 PGUG_01364 PGUG_01325 PGUG_01325 PGUG_01293 PGUG_01293 PGUG_01239 PGUG_01239 PGUG_01228 PGUG_01228 PGUG_01147 PGUG_01147 PGUG_01126 PGUG_01126 PGUG_01119 PGUG_01119 COQ2 COQ2 PGUG_01088 PGUG_01088 PGUG_02716 PGUG_02716 PGUG_05085 PGUG_05085 PGUG_05127 PGUG_05127 PGUG_05132 PGUG_05132 PGUG_02730 PGUG_02730 PGUG_05167 PGUG_05167 PGUG_05203 PGUG_05203 PGUG_05225 PGUG_05225 PGUG_00050 PGUG_00050 PGUG_00055 PGUG_00055 PGUG_00079 PGUG_00079 PGUG_00080 PGUG_00080 PGUG_00098 PGUG_00098 PGUG_00190 PGUG_00190 ARG2 ARG2 PGUG_00207 PGUG_00207 PGUG_00239 PGUG_00239 PGUG_00240 PGUG_00240 PGUG_00255 PGUG_00255 FMN1 FMN1 PGUG_00361 PGUG_00361 DQD1 DQD1 PGUG_00455 PGUG_00455 PGUG_00476 PGUG_00476 PGUG_00494 PGUG_00494 RIB5 RIB5 PGUG_00513 PGUG_00513 PGUG_00514 PGUG_00514 PGUG_00515 PGUG_00515 PGUG_00520 PGUG_00520 PGUG_00563 PGUG_00563 PGUG_00675 PGUG_00675 PGUG_00676 PGUG_00676 PGUG_00711 PGUG_00711 COQ5 COQ5 PGUG_00730 PGUG_00730 PGUG_00752 PGUG_00752 PGUG_00805 PGUG_00805 PGUG_00821 PGUG_00821 COQ7 COQ7 PGUG_00884 PGUG_00884 PGUG_00926 PGUG_00926 PGUG_00943 PGUG_00943 PGUG_01002 PGUG_01002 PGUG_01023 PGUG_01023 PGUG_01035 PGUG_01035 PGUG_01083 PGUG_01083 MET3 MET3 PGUG_05047 PGUG_05047 PGUG_05036 PGUG_05036 PGUG_05024 PGUG_05024 PGUG_04966 PGUG_04966 PGUG_04946 PGUG_04946 MRI1 MRI1 PGUG_04906 PGUG_04906 PGUG_04871 PGUG_04871 PGUG_04828 PGUG_04828 PGUG_04826 PGUG_04826 PGUG_04787 PGUG_04787 PGUG_04771 PGUG_04771 PGUG_04759 PGUG_04759 PGUG_04712 PGUG_04712 PGUG_04696 PGUG_04696 PGUG_04657 PGUG_04657 PGUG_04648 PGUG_04648 PGUG_04644 PGUG_04644 PGUG_04621 PGUG_04621 PGUG_04583 PGUG_04583 PGUG_04573 PGUG_04573 NCP1 NCP1 PGUG_04554 PGUG_04554 PGUG_04548 PGUG_04548 PGUG_04506 PGUG_04506 PGUG_04505 PGUG_04505 COQ4 COQ4 PGUG_04458 PGUG_04458 PGUG_04402 PGUG_04402 BNA5 BNA5 PGUG_04368 PGUG_04368 PGUG_04359 PGUG_04359 PGUG_04338 PGUG_04338 PGUG_04320 PGUG_04320 PGUG_04311 PGUG_04311 PGUG_04278 PGUG_04278 BNA1 BNA1 PGUG_04243 PGUG_04243 PGUG_04239 PGUG_04239 PGUG_04223 PGUG_04223 PGUG_04220 PGUG_04220 PGUG_04219 PGUG_04219 THI4 THI4 PGUG_04190 PGUG_04190 PGUG_04188 PGUG_04188 PGUG_04175 PGUG_04175 PGUG_04160 PGUG_04160 PGUG_04146 PGUG_04146 PGUG_04111 PGUG_04111 PGUG_04040 PGUG_04040 PGUG_04038 PGUG_04038 PGUG_04024 PGUG_04024 PGUG_03985 PGUG_03985 PGUG_03984 PGUG_03984 PGUG_03982 PGUG_03982 PGUG_03973 PGUG_03973 PGUG_03909 PGUG_03909 PGUG_03895 PGUG_03895 PGUG_03876 PGUG_03876 PGUG_03875 PGUG_03875 PGUG_03856 PGUG_03856 PGUG_03807 PGUG_03807 PGUG_03779 PGUG_03779 PGUG_03768 PGUG_03768 PGUG_03757 PGUG_03757 PGUG_03671 PGUG_03671 PGUG_03670 PGUG_03670 PGUG_03640 PGUG_03640 PGUG_03626 PGUG_03626 PGUG_03620 PGUG_03620 MEU1 MEU1 PGUG_03541 PGUG_03541 PGUG_03519 PGUG_03519 PGUG_03494 PGUG_03494 PGUG_03485 PGUG_03485 PGUG_03480 PGUG_03480 PGUG_03416 PGUG_03416 PGUG_03415 PGUG_03415 PGUG_03380 PGUG_03380 PGUG_03264 PGUG_03264 PGUG_03218 PGUG_03218 PGUG_03168 PGUG_03168 UTR4 UTR4 PGUG_03041 PGUG_03041 PGUG_03008 PGUG_03008 PGUG_03003 PGUG_03003 PGUG_03002 PGUG_03002 PGUG_02928 PGUG_02928 PGUG_02923 PGUG_02923 PGUG_02904 PGUG_02904 PGUG_02894 PGUG_02894 PGUG_02870 PGUG_02870 MDE1 MDE1 PGUG_02850 PGUG_02850 PGUG_02836 PGUG_02836 PGUG_02768 PGUG_02768 PGUG_02766 PGUG_02766 PGUG_02742 PGUG_02742
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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PGUG_02757Alkyl transferase; Belongs to the UPP synthase family. (318 aa)
RIB1GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (332 aa)
PGUG_058733Beta_HSD domain-containing protein. (357 aa)
PGUG_05840AB hydrolase-1 domain-containing protein. (498 aa)
COQ6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (492 aa)
PGUG_05631Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (312 aa)
PGUG_05628Argininosuccinate lyase. (464 aa)
PGUG_05611Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
PGUG_05560HEM4 domain-containing protein. (262 aa)
PGUG_05559ANK_REP_REGION domain-containing protein. (1113 aa)
PGUG_05558Phos_pyr_kin domain-containing protein. (317 aa)
PGUG_05557Uncharacterized protein. (355 aa)
PGUG_05535Uncharacterized protein; Belongs to the precorrin methyltransferase family. (535 aa)
MCR1NADH-cytochrome b5 reductase 2; May mediate the reduction of outer membrane cytochrome b5. Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (294 aa)
PGUG_05447Uncharacterized protein. (328 aa)
PGUG_053961-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (267 aa)
PGUG_05380Aminotran_1_2 domain-containing protein. (511 aa)
PGUG_05378Aspartokinase. (528 aa)
PGUG_05365Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family. (370 aa)
BNA4Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (449 aa)
PGUG_05322PKS_ER domain-containing protein. (387 aa)
PGUG_05319Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (807 aa)
PGUG_05303ATP-grasp domain-containing protein. (557 aa)
PGUG_05302ATP-grasp domain-containing protein. (541 aa)
PGUG_05253Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (318 aa)
PGUG_05252Glutamine amidotransferase type-1 domain-containing protein. (432 aa)
PGUG_05240Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (291 aa)
PGUG_02708Uncharacterized protein. (158 aa)
PGUG_02684FAD-binding FR-type domain-containing protein. (521 aa)
PGUG_02670Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family. (309 aa)
PGUG_02623Uncharacterized protein. (253 aa)
PGUG_02619NMT1 domain-containing protein. (338 aa)
PGUG_02603Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (469 aa)
PGUG_02590Polyketide_cyc domain-containing protein. (201 aa)
PGUG_02577Aminotran_1_2 domain-containing protein. (402 aa)
PGUG_02562Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (475 aa)
PGUG_02536Uncharacterized protein. (443 aa)
PGUG_02506Zn(2)-C6 fungal-type domain-containing protein. (444 aa)
PGUG_02477Ribose-phosphate pyrophosphokinase 1. (320 aa)
PGUG_02458Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (396 aa)
PGUG_02417Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (512 aa)
PGUG_02404GHMP_kinases_C domain-containing protein. (277 aa)
PGUG_02402GHMP_kinases_N domain-containing protein. (247 aa)
PGUG_02400Prephenate dehydrogenase [NADP(+)]; Belongs to the prephenate/arogenate dehydrogenase family. (438 aa)
PGUG_02382Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the radical SAM superfamily. Lipoyl synthase family. (385 aa)
PGUG_02360Beta_elim_lyase domain-containing protein. (375 aa)
ADI11,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (178 aa)
PGUG_02272Aminotran_5 domain-containing protein. (296 aa)
PGUG_02270Threonine dehydratase. (583 aa)
PGUG_02249Aldedh domain-containing protein. (438 aa)
PGUG_02240ADH_N domain-containing protein. (256 aa)
PGUG_02229Uncharacterized protein. (608 aa)
PGUG_02219Uncharacterized protein. (217 aa)
PGUG_02209Elongation of fatty acids protein. (331 aa)
PGUG_02174Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1167 aa)
PGUG_021733-hydroxyacyl-[acyl-carrier-protein] dehydratase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The beta subunit contains domains for: [acyl-carrier-protein] acetyltransferase and malonyltransferase, S-acyl fatty acid synthase thioesterase, enoyl- [acyl-carrier-protein] reductase, and 3-hydroxypalmitoyl-[acyl-carrier- protein] dehydratase. (2074 aa)
PGUG_02125Kinase; Belongs to the inositol phosphokinase (IPK) family. (322 aa)
PGUG_02122S5A_REDUCTASE domain-containing protein. (270 aa)
PGUG_02118Glutamine amidotransferase type-2 domain-containing protein. (573 aa)
PGUG_021053-oxoacyl-[acyl-carrier-protein] reductase. (1880 aa)
PGUG_02101Uncharacterized protein. (767 aa)
PGUG_02078Aminotran_1_2 domain-containing protein. (487 aa)
PGUG_02075Uncharacterized protein. (403 aa)
PGUG_02052Uncharacterized protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (339 aa)
PGUG_02024ABC1 domain-containing protein. (555 aa)
PGUG_02009Uncharacterized protein. (308 aa)
PGUG_01980Uncharacterized protein. (2203 aa)
PGUG_01908Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (385 aa)
PGUG_01897Uncharacterized protein. (179 aa)
ERT1Transcription activator of gluconeogenesis ERT1; Transcription factor which regulates nonfermentable carbon utilization. Activator of gluconeogenetic genes (By similarity). Belongs to the ERT1/acuK family. (468 aa)
PGUG_01843N-acetyltransferase domain-containing protein; In the N-terminal section; belongs to the acetylglutamate kinase family. (880 aa)
PGUG_01831Uncharacterized protein. (309 aa)
PGUG_018243-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (432 aa)
PGUG_01797Pyruvate carboxyltransferase domain-containing protein. (524 aa)
PGUG_01763Glutamine amidotransferase type-1 domain-containing protein. (496 aa)
PGUG_01720DAGKc domain-containing protein. (499 aa)
PGUG_01716D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (464 aa)
PGUG_01677Uncharacterized protein. (528 aa)
PGUG_01645AB hydrolase-1 domain-containing protein. (567 aa)
PGUG_01631ACT domain-containing protein. (291 aa)
PGUG_01629Zn(2)-C6 fungal-type domain-containing protein. (967 aa)
PGUG_01529Uncharacterized protein; Belongs to the ketol-acid reductoisomerase family. (404 aa)
PGUG_01505Histidine biosynthesis trifunctional protein. (844 aa)
PGUG_01501Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (642 aa)
PGUG_01496Uncharacterized protein. (282 aa)
PGUG_01489Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
PGUG_01480Homocitrate synthase, mitochondrial; Belongs to the alpha-IPM synthase/homocitrate synthase family. (447 aa)
PGUG_01467Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (388 aa)
PGUG_01426Pribosyltran domain-containing protein. (218 aa)
PGUG_01424Ceramide very long chain fatty acid hydroxylase; Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2; Belongs to the sterol desaturase family. SCS7 subfamily. (378 aa)
PGUG_01420Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (674 aa)
PGUG_01405Triosephosphate isomerase. (248 aa)
PGUG_01382Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (276 aa)
PGUG_01379Uncharacterized protein. (437 aa)
PGUG_01375Ornithine aminotransferase. (432 aa)
PGUG_01364Aminotran_1_2 domain-containing protein. (400 aa)
PGUG_01325Flavodoxin-like domain-containing protein. (1517 aa)
PGUG_01293Methyltransf_11 domain-containing protein. (318 aa)
PGUG_01239Phosphoenolpyruvate carboxykinase. (610 aa)
PGUG_01228DAGKc domain-containing protein. (375 aa)
PGUG_011473-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (773 aa)
PGUG_01126Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (293 aa)
PGUG_01119PUA domain-containing protein. (420 aa)
COQ24-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (380 aa)
PGUG_01088Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (217 aa)
PGUG_02716DAHP_synth_1 domain-containing protein. (311 aa)
PGUG_05085Uncharacterized protein; Belongs to the cytochrome P450 family. (520 aa)
PGUG_05127Uncharacterized protein. (652 aa)
PGUG_05132Uncharacterized protein. (450 aa)
PGUG_027303-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate. (312 aa)
PGUG_05167Uncharacterized protein. (361 aa)
PGUG_05203PMSR domain-containing protein. (184 aa)
PGUG_05225NADPH:adrenodoxin oxidoreductase, mitochondrial. (511 aa)
PGUG_00050S5A_REDUCTASE domain-containing protein. (313 aa)
PGUG_00055Uncharacterized protein. (416 aa)
PGUG_00079ACPS domain-containing protein. (292 aa)
PGUG_00080Beta_elim_lyase domain-containing protein. (369 aa)
PGUG_00098Aminotran_1_2 domain-containing protein. (577 aa)
PGUG_00190Phospho-2-dehydro-3-deoxyheptonate aldolase. (366 aa)
ARG2Amino-acid acetyltransferase, mitochondrial; N-acetylglutamate synthase involved in arginine biosynthesis. Belongs to the acetyltransferase family. (568 aa)
PGUG_00207Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (589 aa)
PGUG_00239Atx10homo_assoc domain-containing protein. (463 aa)
PGUG_00240Uncharacterized protein. (518 aa)
PGUG_00255Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate. (436 aa)
FMN1Riboflavin kinase; Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme; Belongs to the flavokinase family. (180 aa)
PGUG_00361Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family. (412 aa)
DQD1Catabolic 3-dehydroquinase; Is involved in the catabolism of quinate. Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway; Belongs to the type-II 3-dehydroquinase family. (146 aa)
PGUG_00455Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. (524 aa)
PGUG_00476Chorismate mutase. (267 aa)
PGUG_00494Aminotran_1_2 domain-containing protein. (556 aa)
RIB5Riboflavin synthase; Catalyzes the dismutation of two molecules of 6,7-dimethyl-8- ribityllumazine, resulting in the formation of riboflavin and 5-amino- 6-(D-ribitylamino)uracil. (239 aa)
PGUG_00513Alkyl transferase; Belongs to the UPP synthase family. (317 aa)
PGUG_00514Uncharacterized protein. (276 aa)
PGUG_00515Aminotran_5 domain-containing protein. (441 aa)
PGUG_00520Uncharacterized protein. (585 aa)
PGUG_00563NAD(P)-bd_dom domain-containing protein. (382 aa)
PGUG_00675Aminotran_5 domain-containing protein. (428 aa)
PGUG_00676Acetolactate synthase. (681 aa)
PGUG_00711Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (114 aa)
COQ52-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (314 aa)
PGUG_00730Semialdhyde_dh domain-containing protein. (362 aa)
PGUG_00752PfkB domain-containing protein. (347 aa)
PGUG_00805Uncharacterized protein. (2297 aa)
PGUG_00821Uncharacterized protein. (404 aa)
COQ75-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. (263 aa)
PGUG_00884Uncharacterized protein. (255 aa)
PGUG_00926Glucose-6-phosphate isomerase; Belongs to the GPI family. (551 aa)
PGUG_00943Epimerase domain-containing protein. (268 aa)
PGUG_01002Uncharacterized protein. (246 aa)
PGUG_01023Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family. (216 aa)
PGUG_01035Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (493 aa)
PGUG_01083Glutamine synthetase. (371 aa)
MET3Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. Belongs to the sulfate adenylyltransferase family. (523 aa)
PGUG_05047PABS domain-containing protein; Belongs to the spermidine/spermine synthase family. (336 aa)
PGUG_05036Uncharacterized protein. (559 aa)
PGUG_05024Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (287 aa)
PGUG_04966PALP domain-containing protein. (355 aa)
PGUG_04946Pribosyltran domain-containing protein. (186 aa)
MRI1Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (390 aa)
PGUG_04906PALP domain-containing protein. (319 aa)
PGUG_04871Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. (486 aa)
PGUG_04828PALP domain-containing protein. (472 aa)
PGUG_04826Uncharacterized protein. (326 aa)
PGUG_04787Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
PGUG_04771AB hydrolase-1 domain-containing protein. (465 aa)
PGUG_04759Carrier domain-containing protein. (1406 aa)
PGUG_047123-hydroxy-3-methylglutaryl coenzyme A reductase. (1024 aa)
PGUG_04696Uncharacterized protein. (217 aa)
PGUG_04657DJ-1_PfpI domain-containing protein. (287 aa)
PGUG_04648Uncharacterized protein. (355 aa)
PGUG_04644TMP-TENI domain-containing protein. (417 aa)
PGUG_04621Aminotran_1_2 domain-containing protein. (478 aa)
PGUG_04583Uncharacterized protein. (322 aa)
PGUG_04573Uncharacterized protein. (268 aa)
NCP1NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (680 aa)
PGUG_04554Uncharacterized protein. (387 aa)
PGUG_04548Uncharacterized protein. (443 aa)
PGUG_04506Aldedh domain-containing protein. (175 aa)
PGUG_04505Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (313 aa)
COQ4Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides. (313 aa)
PGUG_04458Uncharacterized protein. (2679 aa)
PGUG_04402SE domain-containing protein. (485 aa)
BNA5Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (445 aa)
PGUG_04368Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (277 aa)
PGUG_043592-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (347 aa)
PGUG_04338Glycos_transf_3 domain-containing protein. (256 aa)
PGUG_04320AB hydrolase-1 domain-containing protein. (422 aa)
PGUG_04311Lipid_DES domain-containing protein. (464 aa)
PGUG_042783-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (382 aa)
BNA13-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (169 aa)
PGUG_042433-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (442 aa)
PGUG_04239Sacchrp_dh_C domain-containing protein. (327 aa)
PGUG_04223Uncharacterized protein. (245 aa)
PGUG_04220Uncharacterized protein. (388 aa)
PGUG_04219Kinase; Belongs to the inositol phosphokinase (IPK) family. (637 aa)
THI4Thiamine thiazole synthase; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; Belongs to the T [...] (332 aa)
PGUG_04190Uncharacterized protein. (1613 aa)
PGUG_04188acidPPc domain-containing protein. (283 aa)
PGUG_04175PALP domain-containing protein. (221 aa)
PGUG_04160Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (127 aa)
PGUG_04146AB hydrolase-1 domain-containing protein. (486 aa)
PGUG_04111SGL domain-containing protein. (314 aa)
PGUG_04040ACPS domain-containing protein. (135 aa)
PGUG_04038Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (423 aa)
PGUG_04024Aminotran_5 domain-containing protein. (406 aa)
PGUG_03985SOR_SNZ domain-containing protein; Belongs to the PdxS/SNZ family. (291 aa)
PGUG_03984Uncharacterized protein. (228 aa)
PGUG_03982Homoserine dehydrogenase. (385 aa)
PGUG_03973FBPase domain-containing protein; Belongs to the FBPase class 1 family. (344 aa)
PGUG_03909Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (218 aa)
PGUG_03895Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (453 aa)
PGUG_03876Iso_dh domain-containing protein. (185 aa)
PGUG_03875Iso_dh domain-containing protein. (164 aa)
PGUG_03856DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (213 aa)
PGUG_03807AMP-binding domain-containing protein. (700 aa)
PGUG_03779Glutamine amidotransferase type-1 domain-containing protein. (758 aa)
PGUG_03768Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (469 aa)
PGUG_03757Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1180 aa)
PGUG_03671DHQ_synthase domain-containing protein. (270 aa)
PGUG_036703-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. Belongs to the EPSP synthase family. In the 3rd section; belongs to the shikimate kinase family. In the C-terminal section; belongs to the shikimate dehydrogenase family. (1210 aa)
PGUG_03640Uncharacterized protein. (417 aa)
PGUG_03626PRAI domain-containing protein. (255 aa)
PGUG_03620Pyruvate carboxyltransferase domain-containing protein. (590 aa)
MEU1S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (348 aa)
PGUG_03541Uncharacterized protein. (399 aa)
PGUG_03519Uncharacterized protein. (469 aa)
PGUG_03494Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (122 aa)
PGUG_03485Aspartate aminotransferase. (421 aa)
PGUG_03480Chorismate synthase. (379 aa)
PGUG_03416GHMP_kinases_N domain-containing protein. (350 aa)
PGUG_03415Uncharacterized protein; Belongs to the cytochrome P450 family. (522 aa)
PGUG_03380Folic acid synthesis protein fol1; Catalyzes three sequential steps of tetrahydrofolate biosynthesis; In the C-terminal section; belongs to the DHPS family. In the central section; belongs to the HPPK family. (772 aa)
PGUG_03264SGL domain-containing protein. (326 aa)
PGUG_03218PABS domain-containing protein; Belongs to the spermidine/spermine synthase family. (304 aa)
PGUG_03168PALP domain-containing protein. (427 aa)
UTR4Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (233 aa)
PGUG_03041GTP_cyclohydroI domain-containing protein. (261 aa)
PGUG_03008Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (514 aa)
PGUG_03003Uncharacterized protein. (302 aa)
PGUG_03002Uncharacterized protein. (268 aa)
PGUG_02928FA_desaturase domain-containing protein. (417 aa)
PGUG_02923Elongation of fatty acids protein. (319 aa)
PGUG_02904Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (461 aa)
PGUG_02894Inos-1-P_synth domain-containing protein. (518 aa)
PGUG_02870Uncharacterized protein. (121 aa)
MDE1Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). (262 aa)
PGUG_02850Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (245 aa)
PGUG_02836IMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation. (478 aa)
PGUG_02768Elongation of fatty acids protein. (332 aa)
PGUG_02766RibD_C domain-containing protein. (281 aa)
PGUG_027423,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (202 aa)
Your Current Organism:
Meyerozyma guilliermondii
NCBI taxonomy Id: 294746
Other names: M. guilliermondii ATCC 6260, Meyerozyma guilliermondii ATCC 6260, Pichia guilliermondii ATCC 6260
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