(13 nodes) Cell redox homeostasis network (Meyerozyma guilliermondii)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	PGUG_01180	Dihydrolipoyl dehydrogenase. (493 aa)
	PGUG_01590	Thioredoxin domain-containing protein. (315 aa)
	PGUG_02608	Thioredoxin domain-containing protein. (227 aa)
	PGUG_02781	Peroxiredoxin TSA1. (196 aa)
	PGUG_02909	S-(Hydroxymethyl)glutathione dehydrogenase. (254 aa)
	PGUG_03331	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (538 aa)
	PGUG_03867	Thioredoxin domain-containing protein. (256 aa)
	PGUG_04578	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (173 aa)
	PGUG_04876	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (188 aa)
	PGUG_04879	Uncharacterized protein. (1533 aa)
	PGUG_05034	Uncharacterized protein. (552 aa)
	PGUG_05748	Thioredoxin domain-containing protein. (224 aa)
	PGUG_05808	Uncharacterized protein. (622 aa)

Your Current Organism:

Meyerozyma guilliermondii

NCBI taxonomy Id: 294746
Other names: M. guilliermondii ATCC 6260, Meyerozyma guilliermondii ATCC 6260, Pichia guilliermondii ATCC 6260

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PGUG_01180	PGUG_02608	A5DD25	A5DH57	Dihydrolipoyl dehydrogenase.	Thioredoxin domain-containing protein.	0.414
PGUG_01180	PGUG_02909	A5DD25	A5DI08	Dihydrolipoyl dehydrogenase.	S-(Hydroxymethyl)glutathione dehydrogenase.	0.437
PGUG_01180	PGUG_04578	A5DD25	A5DMS7	Dihydrolipoyl dehydrogenase.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.586
PGUG_01180	PGUG_04876	A5DD25	A5DNM5	Dihydrolipoyl dehydrogenase.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.586
PGUG_02608	PGUG_01180	A5DH57	A5DD25	Thioredoxin domain-containing protein.	Dihydrolipoyl dehydrogenase.	0.414
PGUG_02608	PGUG_03331	A5DH57	A5DJ80	Thioredoxin domain-containing protein.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.465
PGUG_02608	PGUG_04578	A5DH57	A5DMS7	Thioredoxin domain-containing protein.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.408
PGUG_02781	PGUG_03331	A5DHN0	A5DJ80	Peroxiredoxin TSA1.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.658
PGUG_02781	PGUG_04578	A5DHN0	A5DMS7	Peroxiredoxin TSA1.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.819
PGUG_02781	PGUG_04876	A5DHN0	A5DNM5	Peroxiredoxin TSA1.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.819
PGUG_02909	PGUG_01180	A5DI08	A5DD25	S-(Hydroxymethyl)glutathione dehydrogenase.	Dihydrolipoyl dehydrogenase.	0.437
PGUG_03331	PGUG_02608	A5DJ80	A5DH57	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Thioredoxin domain-containing protein.	0.465
PGUG_03331	PGUG_02781	A5DJ80	A5DHN0	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Peroxiredoxin TSA1.	0.658
PGUG_03331	PGUG_03867	A5DJ80	A5DKR6	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Thioredoxin domain-containing protein.	0.938
PGUG_03331	PGUG_04578	A5DJ80	A5DMS7	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.637
PGUG_03331	PGUG_04876	A5DJ80	A5DNM5	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.637
PGUG_03331	PGUG_05748	A5DJ80	A5DR47	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Thioredoxin domain-containing protein.	0.938
PGUG_03867	PGUG_03331	A5DKR6	A5DJ80	Thioredoxin domain-containing protein.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.938
PGUG_03867	PGUG_04578	A5DKR6	A5DMS7	Thioredoxin domain-containing protein.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.572
PGUG_03867	PGUG_04876	A5DKR6	A5DNM5	Thioredoxin domain-containing protein.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.572