STRINGSTRING
PGUG_03304 PGUG_03304 PGUG_03247 PGUG_03247 PGUG_03211 PGUG_03211 PGUG_03205 PGUG_03205 SLX4 SLX4 PGUG_03191 PGUG_03191 PGUG_03144 PGUG_03144 PGUG_03122 PGUG_03122 PGUG_03117 PGUG_03117 PGUG_03097 PGUG_03097 PGUG_03056 PGUG_03056 PGUG_03040 PGUG_03040 PGUG_02934 PGUG_02934 PGUG_02892 PGUG_02892 PGUG_02862 PGUG_02862 PGUG_02826 PGUG_02826 PGUG_02821 PGUG_02821 PGUG_02753 PGUG_02753 PGUG_02748 PGUG_02748 PGUG_02741 PGUG_02741 PGUG_02613 PGUG_02613 PGUG_02523 PGUG_02523 PGUG_02512 PGUG_02512 PGUG_02442 PGUG_02442 PGUG_02412 PGUG_02412 PGUG_02338 PGUG_02338 PGUG_02275 PGUG_02275 SLX1 SLX1 PGUG_02172 PGUG_02172 PGUG_02066 PGUG_02066 PGUG_02013 PGUG_02013 PGUG_01937 PGUG_01937 PGUG_01896 PGUG_01896 PGUG_01849 PGUG_01849 PGUG_01793 PGUG_01793 PGUG_01771 PGUG_01771 PGUG_01749 PGUG_01749 PGUG_01731 PGUG_01731 PGUG_01719 PGUG_01719 PGUG_01694 PGUG_01694 PGUG_01673 PGUG_01673 PGUG_01656 PGUG_01656 PGUG_01600 PGUG_01600 PGUG_01593 PGUG_01593 PGUG_01548 PGUG_01548 PGUG_01499 PGUG_01499 PGUG_01485 PGUG_01485 PGUG_01395 PGUG_01395 PGUG_01394 PGUG_01394 PGUG_01358 PGUG_01358 NTG1 NTG1 PGUG_00399 PGUG_00399 PGUG_00302 PGUG_00302 PGUG_00300 PGUG_00300 PGUG_00268 PGUG_00268 PGUG_00249 PGUG_00249 PAN2 PAN2 PGUG_00217 PGUG_00217 PGUG_00151 PGUG_00151 PGUG_00146 PGUG_00146 PGUG_00145 PGUG_00145 PGUG_00084 PGUG_00084 PGUG_00083 PGUG_00083 PGUG_00082 PGUG_00082 PGUG_00067 PGUG_00067 PGUG_00056 PGUG_00056 PGUG_00040 PGUG_00040 PGUG_00131 PGUG_00131 PGUG_00412 PGUG_00412 PGUG_00433 PGUG_00433 PGUG_00438 PGUG_00438 PGUG_00445 PGUG_00445 PGUG_00465 PGUG_00465 PGUG_00540 PGUG_00540 PGUG_00555 PGUG_00555 PGUG_00603 PGUG_00603 PGUG_00649 PGUG_00649 PGUG_00686 PGUG_00686 PGUG_00688 PGUG_00688 PGUG_00826 PGUG_00826 PGUG_00876 PGUG_00876 PGUG_00905 PGUG_00905 FEN1 FEN1 PGUG_00985 PGUG_00985 PGUG_01010 PGUG_01010 PGUG_01015 PGUG_01015 PGUG_01031 PGUG_01031 PGUG_01037 PGUG_01037 PGUG_00402 PGUG_00402 PGUG_01038 PGUG_01038 PGUG_01045 PGUG_01045 PGUG_01050 PGUG_01050 PGUG_01104 PGUG_01104 PGUG_01165 PGUG_01165 PGUG_01184 PGUG_01184 PGUG_01227 PGUG_01227 PGUG_01232 PGUG_01232 PGUG_01233 PGUG_01233 PGUG_01242 PGUG_01242 PGUG_01273 PGUG_01273 PGUG_01287 PGUG_01287 PGUG_01290 PGUG_01290 PGUG_05916 PGUG_05916 PGUG_05902 PGUG_05902 PGUG_05901 PGUG_05901 PGUG_05741 PGUG_05741 PGUG_05645 PGUG_05645 PGUG_05494 PGUG_05494 PGUG_05450 PGUG_05450 PGUG_05431 PGUG_05431 PGUG_05282 PGUG_05282 PGUG_05250 PGUG_05250 PGUG_05154 PGUG_05154 PGUG_05017 PGUG_05017 LCL3 LCL3 PGUG_04669 PGUG_04669 PGUG_04662 PGUG_04662 PGUG_04645 PGUG_04645 PGUG_04570 PGUG_04570 PGUG_04543 PGUG_04543 PGUG_04533 PGUG_04533 PGUG_04457 PGUG_04457 PGUG_04348 PGUG_04348 PGUG_04303 PGUG_04303 PGUG_04297 PGUG_04297 PGUG_04251 PGUG_04251 PGUG_04191 PGUG_04191 PGUG_04138 PGUG_04138 PGUG_04129 PGUG_04129 RRP36 RRP36 PGUG_04029 PGUG_04029 PGUG_04013 PGUG_04013 PGUG_03810 PGUG_03810 PGUG_03785 PGUG_03785 PGUG_03677 PGUG_03677 PGUG_03660 PGUG_03660 PGUG_03483 PGUG_03483 PGUG_03448 PGUG_03448 PGUG_03447 PGUG_03447 PGUG_03446 PGUG_03446 PGUG_03402 PGUG_03402
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PGUG_03304KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (340 aa)
PGUG_03247Ydc2-catalyt domain-containing protein. (316 aa)
PGUG_03211Endo/exonuclease/phosphatase domain-containing protein. (290 aa)
PGUG_03205tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...] (372 aa)
SLX4Structure-specific endonuclease subunit SLX4; Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (681 aa)
PGUG_03191Exonuclease domain-containing protein. (455 aa)
PGUG_03144Exonuclease domain-containing protein. (495 aa)
PGUG_03122RNase III domain-containing protein. (338 aa)
PGUG_03117Uncharacterized protein. (1170 aa)
PGUG_03097WD_REPEATS_REGION domain-containing protein. (362 aa)
PGUG_03056Uncharacterized protein; Belongs to the RNase T2 family. (401 aa)
PGUG_03040RNB domain-containing protein. (1258 aa)
PGUG_02934ERCC4 domain-containing protein. (601 aa)
PGUG_02892Uncharacterized protein. (270 aa)
PGUG_02862Uncharacterized protein. (1403 aa)
PGUG_02826PINc domain-containing protein. (214 aa)
PGUG_02821Uncharacterized protein. (778 aa)
PGUG_02753Brix domain-containing protein. (310 aa)
PGUG_02748Exonuclease domain-containing protein. (310 aa)
PGUG_02741Uncharacterized protein; Belongs to the RNR ribonuclease family. (978 aa)
PGUG_02613Lactamase_B_4 domain-containing protein. (870 aa)
PGUG_02523Uncharacterized protein. (1035 aa)
PGUG_02512Uncharacterized protein. (164 aa)
PGUG_02442Cleavage and polyadenylation specificity factor subunit 2. (821 aa)
PGUG_02412Uncharacterized protein. (242 aa)
PGUG_02338RNB domain-containing protein; Belongs to the RNR ribonuclease family. (1095 aa)
PGUG_02275Uncharacterized protein. (770 aa)
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (295 aa)
PGUG_02172Endonuclease. (325 aa)
PGUG_02066Endo/exonuclease/phosphatase domain-containing protein. (444 aa)
PGUG_02013Uncharacterized protein. (313 aa)
PGUG_01937Bms1-type G domain-containing protein. (771 aa)
PGUG_01896Protein DOM34 homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (372 aa)
PGUG_01849RAI1 domain-containing protein. (394 aa)
PGUG_01793TP6A_N domain-containing protein. (315 aa)
PGUG_01771RNase III domain-containing protein. (617 aa)
PGUG_01749tRNA_int_end_N2 domain-containing protein. (425 aa)
PGUG_01731Uncharacterized protein. (312 aa)
PGUG_01719Endo/exonuclease/phosphatase domain-containing protein. (310 aa)
PGUG_01694WD_REPEATS_REGION domain-containing protein. (487 aa)
PGUG_01673Uncharacterized protein. (367 aa)
PGUG_01656Uncharacterized protein. (749 aa)
PGUG_01600Uncharacterized protein. (859 aa)
PGUG_01593Uncharacterized protein. (894 aa)
PGUG_01548Uncharacterized protein. (638 aa)
PGUG_01499ERCC4 domain-containing protein. (1020 aa)
PGUG_01485Uncharacterized protein. (566 aa)
PGUG_01395DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (111 aa)
PGUG_01394Lactamase_B domain-containing protein. (651 aa)
PGUG_01358Uncharacterized protein. (402 aa)
NTG1Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (455 aa)
PGUG_00399Exonuclease domain-containing protein. (288 aa)
PGUG_00302zf-C2HE domain-containing protein. (242 aa)
PGUG_00300Uncharacterized protein. (520 aa)
PGUG_00268RNase H domain-containing protein. (152 aa)
PGUG_00249Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (151 aa)
PAN2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1098 aa)
PGUG_002173'-5' exonuclease domain-containing protein. (755 aa)
PGUG_00151Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (343 aa)
PGUG_00146Uncharacterized protein. (422 aa)
PGUG_00145Endo/exonuclease/phosphatase domain-containing protein. (497 aa)
PGUG_00084Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (264 aa)
PGUG_00083RNase H domain-containing protein. (243 aa)
PGUG_00082Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (260 aa)
PGUG_00067DNA polymerase. (1075 aa)
PGUG_00056Uncharacterized protein. (537 aa)
PGUG_00040U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA. (243 aa)
PGUG_00131Endo/exonuclease/phosphatase domain-containing protein. (364 aa)
PGUG_00412PINc domain-containing protein. (433 aa)
PGUG_00433Uncharacterized protein. (373 aa)
PGUG_00438DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (123 aa)
PGUG_00445DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (112 aa)
PGUG_00465Uncharacterized protein. (269 aa)
PGUG_00540Uncharacterized protein. (249 aa)
PGUG_00555TRAM domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (532 aa)
PGUG_0060320S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family. (485 aa)
PGUG_00649AAA_23 domain-containing protein. (1302 aa)
PGUG_00686Bms1-type G domain-containing protein. (1177 aa)
PGUG_00688Uncharacterized protein. (474 aa)
PGUG_00826Uncharacterized protein. (525 aa)
PGUG_00876Uncharacterized protein. (551 aa)
PGUG_00905POLAc domain-containing protein. (1209 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (374 aa)
PGUG_00985Uncharacterized protein. (199 aa)
PGUG_01010tRNA_int_endo domain-containing protein. (232 aa)
PGUG_01015Uncharacterized protein. (417 aa)
PGUG_01031Uncharacterized protein. (509 aa)
PGUG_01037RRM domain-containing protein. (242 aa)
PGUG_00402Plus3 domain-containing protein. (539 aa)
PGUG_01038RRM domain-containing protein. (326 aa)
PGUG_01045Uncharacterized protein. (389 aa)
PGUG_010505'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. (1378 aa)
PGUG_01104Uncharacterized protein. (267 aa)
PGUG_01165DRMBL domain-containing protein. (736 aa)
PGUG_01184Fcf2 domain-containing protein. (193 aa)
PGUG_012275'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (909 aa)
PGUG_01232PINc domain-containing protein. (212 aa)
PGUG_01233Uncharacterized protein. (808 aa)
PGUG_01242XPGI domain-containing protein. (632 aa)
PGUG_01273WD_REPEATS_REGION domain-containing protein. (780 aa)
PGUG_01287WD_REPEATS_REGION domain-containing protein. (956 aa)
PGUG_01290Endo/exonuclease/phosphatase domain-containing protein. (720 aa)
PGUG_05916COX1 domain-containing protein. (168 aa)
PGUG_05902Uncharacterized protein. (445 aa)
PGUG_05901Uncharacterized protein. (414 aa)
PGUG_05741Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (217 aa)
PGUG_05645Endo/exonuclease/phosphatase domain-containing protein. (308 aa)
PGUG_05494DBR1 domain-containing protein. (392 aa)
PGUG_05450Uncharacterized protein. (840 aa)
PGUG_05431Uncharacterized protein. (511 aa)
PGUG_05282Uncharacterized protein. (1674 aa)
PGUG_05250Uncharacterized protein. (306 aa)
PGUG_05154Uncharacterized protein. (319 aa)
PGUG_05017Uncharacterized protein. (1060 aa)
LCL3Probable endonuclease LCL3. (228 aa)
PGUG_04669XPA_C domain-containing protein. (375 aa)
PGUG_04662Uncharacterized protein. (537 aa)
PGUG_04645Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Belongs to the eukaryotic/archaeal RNase P protein component 2 family. (145 aa)
PGUG_04570XPGI domain-containing protein. (846 aa)
PGUG_04543Uncharacterized protein. (330 aa)
PGUG_04533RNase_PH domain-containing protein. (314 aa)
PGUG_04457RNase_PH domain-containing protein. (325 aa)
PGUG_04348Uncharacterized protein. (285 aa)
PGUG_04303Helicase ATP-binding domain-containing protein. (843 aa)
PGUG_04297Uncharacterized protein. (543 aa)
PGUG_04251Uncharacterized protein. (1243 aa)
PGUG_04191Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (641 aa)
PGUG_04138CBF domain-containing protein. (532 aa)
PGUG_04129RNase_PH domain-containing protein. (221 aa)
RRP36rRNA biogenesis protein RRP36; Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity). (267 aa)
PGUG_04029RNase_PH domain-containing protein. (252 aa)
PGUG_04013Uncharacterized protein. (478 aa)
PGUG_03810ERCC4 domain-containing protein. (287 aa)
PGUG_03785Kri1_C domain-containing protein. (554 aa)
PGUG_03677Uncharacterized protein. (635 aa)
PGUG_03660CID domain-containing protein. (427 aa)
PGUG_03483Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
PGUG_03448DRIM domain-containing protein. (1622 aa)
PGUG_03447Uncharacterized protein. (364 aa)
PGUG_03446Uncharacterized protein. (385 aa)
PGUG_03402Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (554 aa)
Your Current Organism:
Meyerozyma guilliermondii
NCBI taxonomy Id: 294746
Other names: M. guilliermondii ATCC 6260, Meyerozyma guilliermondii ATCC 6260, Pichia guilliermondii ATCC 6260
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