63 items (Meyerozyma guilliermondii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PGUG_03104	Uncharacterized protein. (176 aa)
	PGUG_03103	DNA_pol_E_B domain-containing protein. (213 aa)
	PGUG_03102	Pol_alpha_B_N domain-containing protein. (193 aa)
	PGUG_03017	RPOL4c domain-containing protein. (148 aa)
	RPB2	DNA-directed RNA polymerase II subunit RPB2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB2 is [...] (1236 aa)
	PGUG_02831	Uncharacterized protein. (173 aa)
	PGUG_02765	DNA-directed RNA polymerases II 24 kDa polypeptide. (179 aa)
	PGUG_02671	Uncharacterized protein. (146 aa)
	PGUG_02490	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (331 aa)
	PGUG_02478	TAFII55_N domain-containing protein. (501 aa)
	PGUG_02475	Uncharacterized protein. (186 aa)
	PGUG_02408	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (532 aa)
	PGUG_02223	TAF8_C domain-containing protein. (529 aa)
	PGUG_01774	Uncharacterized protein. (239 aa)
	PGUG_01783	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (269 aa)
	PGUG_01872	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (148 aa)
	PGUG_02050	DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (306 aa)
	PGUG_02059	Uncharacterized protein. (1601 aa)
	PGUG_02088	Uncharacterized protein. (380 aa)
	PGUG_05580	TAFII28 domain-containing protein. (241 aa)
	RPC82	DNA-directed RNA polymerase III subunit RPC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (By similarity). (588 aa)
	PGUG_05450	Uncharacterized protein. (840 aa)
	PGUG_05425	Uncharacterized protein. (158 aa)
	PGUG_05395	RPOLD domain-containing protein. (305 aa)
	PGUG_05316	RPOLD domain-containing protein. (333 aa)
	PGUG_05248	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (123 aa)
	PGUG_05134	Uncharacterized protein. (415 aa)
	PGUG_05071	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (211 aa)
	PGUG_04989	Uncharacterized protein. (73 aa)
	PGUG_04942	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (488 aa)
	PGUG_04749	CDC73_C domain-containing protein. (373 aa)
	PGUG_04305	Uncharacterized protein. (373 aa)
	PGUG_04303	Helicase ATP-binding domain-containing protein. (843 aa)
	PGUG_04236	Uncharacterized protein. (317 aa)
	PGUG_04124	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (492 aa)
	PGUG_04108	CYCLIN domain-containing protein; Belongs to the cyclin family. (385 aa)
	PGUG_01300	TAF domain-containing protein. (489 aa)
	RPB1	DNA-directed RNA polymerase II subunit RPB1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cl [...] (1579 aa)
	PGUG_01107	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (288 aa)
	PGUG_00968	Uncharacterized protein. (699 aa)
	PGUG_05851	Uncharacterized protein. (69 aa)
	PGUG_05648	Uncharacterized protein. (410 aa)
	PGUG_04106	Uncharacterized protein. (356 aa)
	PGUG_04095	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (498 aa)
	PGUG_04052	Uncharacterized protein. (72 aa)
	PGUG_04032	RNA_pol_L_2 domain-containing protein. (123 aa)
	PGUG_00438	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (123 aa)
	TAF4	Transcription initiation factor TFIID subunit 4; Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of tra [...] (455 aa)
	PGUG_00409	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1166 aa)
	PGUG_00402	Plus3 domain-containing protein. (539 aa)
	PGUG_00366	Uncharacterized protein. (274 aa)
	PGUG_00298	BTP domain-containing protein. (263 aa)
	PGUG_00182	WD_REPEATS_REGION domain-containing protein. (387 aa)
	PGUG_00134	BSD domain-containing protein. (620 aa)
	PGUG_00860	DNA polymerase. (1438 aa)
	PGUG_00511	DNA primase; Belongs to the eukaryotic-type primase small subunit family. (464 aa)
	PGUG_00445	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (112 aa)
	PGUG_01460	RPOL4c domain-containing protein. (188 aa)
	PGUG_03796	Uncharacterized protein. (378 aa)
	PGUG_03680	RING-type domain-containing protein. (321 aa)
	PGUG_03608	HTH TFE/IIEalpha-type domain-containing protein. (380 aa)
	PGUG_03501	Uncharacterized protein. (1074 aa)
	PGUG_03110	Uncharacterized protein. (1056 aa)

Your Current Organism:

Meyerozyma guilliermondii

NCBI taxonomy Id: 294746
Other names: M. guilliermondii ATCC 6260, Meyerozyma guilliermondii ATCC 6260, Pichia guilliermondii ATCC 6260

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PGUG_00134	PGUG_00409	A5DA29	A5DAV4	BSD domain-containing protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.831
PGUG_00134	PGUG_00438	A5DA29	A5DAY3	BSD domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.760
PGUG_00134	PGUG_00445	A5DA29	A5DAZ0	BSD domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.932
PGUG_00134	PGUG_00968	A5DA29	A5DCG3	BSD domain-containing protein.	Uncharacterized protein.	0.745
PGUG_00134	PGUG_01107	A5DA29	A5DCV2	BSD domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.917
PGUG_00134	PGUG_01300	A5DA29	A5DDE9	BSD domain-containing protein.	TAF domain-containing protein.	0.764
PGUG_00134	PGUG_01460	A5DA29	A5DDV9	BSD domain-containing protein.	RPOL4c domain-containing protein.	0.938
PGUG_00134	PGUG_01783	A5DA29	A5DET2	BSD domain-containing protein.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.995
PGUG_00134	PGUG_01872	A5DA29	A5DF21	BSD domain-containing protein.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.933
PGUG_00134	PGUG_02059	A5DA29	A5DFK8	BSD domain-containing protein.	Uncharacterized protein.	0.773
PGUG_00134	PGUG_02088	A5DA29	A5DFN7	BSD domain-containing protein.	Uncharacterized protein.	0.937
PGUG_00134	PGUG_02408	A5DA29	A5DGK7	BSD domain-containing protein.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.960
PGUG_00134	PGUG_02475	A5DA29	A5DGS4	BSD domain-containing protein.	Uncharacterized protein.	0.763
PGUG_00134	PGUG_02478	A5DA29	A5DGS7	BSD domain-containing protein.	TAFII55_N domain-containing protein.	0.745
PGUG_00134	PGUG_02490	A5DA29	A5DGT9	BSD domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.965
PGUG_00134	PGUG_02671	A5DA29	A5DHC0	BSD domain-containing protein.	Uncharacterized protein.	0.750
PGUG_00134	PGUG_02765	A5DA29	A5DHL4	BSD domain-containing protein.	DNA-directed RNA polymerases II 24 kDa polypeptide.	0.932
PGUG_00134	PGUG_02831	A5DA29	A5DHT0	BSD domain-containing protein.	Uncharacterized protein.	0.932
PGUG_00134	PGUG_03110	A5DA29	A5DIK9	BSD domain-containing protein.	Uncharacterized protein.	0.745
PGUG_00134	PGUG_03608	A5DA29	A5DK07	BSD domain-containing protein.	HTH TFE/IIEalpha-type domain-containing protein.	0.997