(6 nodes) MCM domain network (Meyerozyma guilliermondii)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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experimentally determined

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gene neighborhood

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textmining

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protein homology

Your Input:
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (797 aa)
	PGUG_02276	DNA helicase; Belongs to the MCM family. (766 aa)
	PGUG_03230	DNA helicase; Belongs to the MCM family. (902 aa)
	PGUG_03863	MCM domain-containing protein; Belongs to the MCM family. (451 aa)
	PGUG_04139	DNA helicase; Belongs to the MCM family. (837 aa)
	PGUG_00348	DNA helicase; Belongs to the MCM family. (853 aa)

Your Current Organism:

Meyerozyma guilliermondii

NCBI taxonomy Id: 294746
Other names: M. guilliermondii ATCC 6260, Meyerozyma guilliermondii ATCC 6260, Pichia guilliermondii ATCC 6260

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCM7	PGUG_00348	A5DFR1	A5DAP3	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	PGUG_02276	A5DFR1	A5DG75	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	PGUG_03230	A5DFR1	A5DIX9	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	PGUG_03863	A5DFR1	A5DKR2	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	MCM domain-containing protein; Belongs to the MCM family.	0.985
MCM7	PGUG_04139	A5DFR1	A5DLI8	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
PGUG_00348	MCM7	A5DAP3	A5DFR1	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
PGUG_00348	PGUG_02276	A5DAP3	A5DG75	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
PGUG_00348	PGUG_03230	A5DAP3	A5DIX9	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
PGUG_00348	PGUG_03863	A5DAP3	A5DKR2	DNA helicase; Belongs to the MCM family.	MCM domain-containing protein; Belongs to the MCM family.	0.985
PGUG_00348	PGUG_04139	A5DAP3	A5DLI8	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
PGUG_02276	MCM7	A5DG75	A5DFR1	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
PGUG_02276	PGUG_00348	A5DG75	A5DAP3	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
PGUG_02276	PGUG_03230	A5DG75	A5DIX9	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
PGUG_02276	PGUG_03863	A5DG75	A5DKR2	DNA helicase; Belongs to the MCM family.	MCM domain-containing protein; Belongs to the MCM family.	0.985
PGUG_02276	PGUG_04139	A5DG75	A5DLI8	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
PGUG_03230	MCM7	A5DIX9	A5DFR1	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
PGUG_03230	PGUG_00348	A5DIX9	A5DAP3	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
PGUG_03230	PGUG_02276	A5DIX9	A5DG75	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
PGUG_03230	PGUG_03863	A5DIX9	A5DKR2	DNA helicase; Belongs to the MCM family.	MCM domain-containing protein; Belongs to the MCM family.	0.986
PGUG_03230	PGUG_04139	A5DIX9	A5DLI8	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999