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PGUG_00406 PGUG_00406 PGUG_00055 PGUG_00055 PGUG_00179 PGUG_00179 PGUG_00306 PGUG_00306 NCS2 NCS2 PGUG_00414 PGUG_00414 PGUG_01065 PGUG_01065 PGUG_01146 PGUG_01146 PGUG_01430 PGUG_01430 PGUG_01899 PGUG_01899 PGUG_02057 PGUG_02057 PGUG_02058 PGUG_02058 PGUG_02085 PGUG_02085 PGUG_02118 PGUG_02118 PGUG_02309 PGUG_02309 PGUG_02395 PGUG_02395 PGUG_02518 PGUG_02518 PGUG_02687 PGUG_02687 PGUG_02743 PGUG_02743 PGUG_02818 PGUG_02818 PGUG_02829 PGUG_02829 PGUG_02855 PGUG_02855 PGUG_03043 PGUG_03043 PGUG_03047 PGUG_03047 PGUG_03186 PGUG_03186 PGUG_03322 PGUG_03322 PGUG_03540 PGUG_03540 PGUG_03555 PGUG_03555 PGUG_03636 PGUG_03636 PGUG_03693 PGUG_03693 PGUG_04041 PGUG_04041 PGUG_04127 PGUG_04127 PGUG_04630 PGUG_04630 PGUG_04938 PGUG_04938 PGUG_04995 PGUG_04995 MET3 MET3 PGUG_05127 PGUG_05127 NCS6 NCS6 PGUG_05447 PGUG_05447 PGUG_05476 PGUG_05476 PGUG_05829 PGUG_05829
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PGUG_00406Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (844 aa)
PGUG_00055Uncharacterized protein. (416 aa)
PGUG_00179Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (590 aa)
PGUG_00306tRNA-synt_1 domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (642 aa)
NCS2Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (420 aa)
PGUG_00414Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (582 aa)
PGUG_01065ETF domain-containing protein. (328 aa)
PGUG_01146Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family. (387 aa)
PGUG_01430Uncharacterized protein. (1093 aa)
PGUG_01899tRNA-synt_1c domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (502 aa)
PGUG_02057Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (1115 aa)
PGUG_02058ATP_bind_3 domain-containing protein. (471 aa)
PGUG_02085Uncharacterized protein. (350 aa)
PGUG_02118Glutamine amidotransferase type-2 domain-containing protein. (573 aa)
PGUG_02309PAPS_reduct domain-containing protein. (258 aa)
PGUG_02395Tyrosine--tRNA ligase. (404 aa)
PGUG_02518CTP_transf_like domain-containing protein. (424 aa)
PGUG_02687Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (368 aa)
PGUG_02743Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (426 aa)
PGUG_02818Uncharacterized protein. (601 aa)
PGUG_02829Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (632 aa)
PGUG_02855ETF domain-containing protein. (255 aa)
PGUG_03043Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (751 aa)
PGUG_03047tRNA-synt_1g domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (565 aa)
PGUG_03186CTP_transf_like domain-containing protein. (273 aa)
PGUG_03322PAPS_reduct domain-containing protein. (181 aa)
PGUG_03540Tyrosine--tRNA ligase. (604 aa)
PGUG_03555CTP_transf_like domain-containing protein. (294 aa)
PGUG_03636tRNA-synt_1e domain-containing protein. (769 aa)
PGUG_03693Diphthami_syn_2 domain-containing protein. (628 aa)
PGUG_04041GMP synthase. (529 aa)
PGUG_04127Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (1065 aa)
PGUG_04630Usp domain-containing protein. (366 aa)
PGUG_04938Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (714 aa)
PGUG_04995Uncharacterized protein. (412 aa)
MET3Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. Belongs to the sulfate adenylyltransferase family. (523 aa)
PGUG_05127Uncharacterized protein. (652 aa)
NCS6Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (369 aa)
PGUG_05447Uncharacterized protein. (328 aa)
PGUG_05476Usp domain-containing protein. (467 aa)
PGUG_05829Photolyase/cryptochrome alpha/beta domain-containing protein. (607 aa)
Your Current Organism:
Meyerozyma guilliermondii
NCBI taxonomy Id: 294746
Other names: M. guilliermondii ATCC 6260, Meyerozyma guilliermondii ATCC 6260, Pichia guilliermondii ATCC 6260
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