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FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (374 aa) | ||||
PGUG_00412 | PINc domain-containing protein. (433 aa) | ||||
PGUG_04570 | XPGI domain-containing protein. (846 aa) | ||||
PGUG_03872 | Uncharacterized protein. (254 aa) | ||||
PGUG_03677 | Uncharacterized protein. (635 aa) | ||||
PGUG_02826 | PINc domain-containing protein. (214 aa) | ||||
PGUG_02741 | Uncharacterized protein; Belongs to the RNR ribonuclease family. (978 aa) | ||||
PGUG_02523 | Uncharacterized protein. (1035 aa) | ||||
PGUG_01242 | XPGI domain-containing protein. (632 aa) | ||||
PGUG_01232 | PINc domain-containing protein. (212 aa) |