STRINGSTRING
PGUG_03429 PGUG_03429 HTB2 HTB2 PGUG_01245 PGUG_01245 PGUG_01246 PGUG_01246 PGUG_02074 PGUG_02074 MTC6 MTC6 PGUG_02429 PGUG_02429 PIF1 PIF1 PGUG_03132 PGUG_03132 PGUG_03368 PGUG_03368 HTB1 HTB1 PGUG_03492 PGUG_03492 PGUG_04153 PGUG_04153 PGUG_04294 PGUG_04294 PGUG_04353 PGUG_04353 PGUG_04687 PGUG_04687 PGUG_04794 PGUG_04794 PGUG_04837 PGUG_04837 PGUG_04902 PGUG_04902 PGUG_05544 PGUG_05544 PGUG_05658 PGUG_05658 PGUG_05709 PGUG_05709 PGUG_05836 PGUG_05836 PGUG_05881 PGUG_05881 PGUG_00249 PGUG_00249
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PGUG_03429CENP-C_C domain-containing protein. (511 aa)
HTB2Histone H2B.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (129 aa)
PGUG_01245Uncharacterized protein. (229 aa)
PGUG_01246ATP-dependent DNA helicase; Belongs to the helicase family. (426 aa)
PGUG_02074Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (469 aa)
MTC6Maintenance of telomere capping protein 6; May be involved in telomere capping; Belongs to the MTC6 family. (568 aa)
PGUG_02429Uncharacterized protein. (130 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (722 aa)
PGUG_03132CENP-T_C domain-containing protein. (646 aa)
PGUG_03368TruB_N domain-containing protein. (412 aa)
HTB1Histone H2B.1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (129 aa)
PGUG_03492H/ACA ribonucleoprotein complex subunit 3. (59 aa)
PGUG_04153Uncharacterized protein. (990 aa)
PGUG_04294Centromere/microtubule-binding protein CBF5. (501 aa)
PGUG_04353RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (458 aa)
PGUG_04687RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (419 aa)
PGUG_04794Uncharacterized protein. (375 aa)
PGUG_04837Uncharacterized protein. (1176 aa)
PGUG_04902Uncharacterized protein. (1034 aa)
PGUG_05544Uncharacterized protein. (370 aa)
PGUG_05658CS domain-containing protein. (444 aa)
PGUG_05709AAA domain-containing protein. (796 aa)
PGUG_05836H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (200 aa)
PGUG_05881Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (878 aa)
PGUG_00249Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (151 aa)
Your Current Organism:
Meyerozyma guilliermondii
NCBI taxonomy Id: 294746
Other names: M. guilliermondii ATCC 6260, Meyerozyma guilliermondii ATCC 6260, Pichia guilliermondii ATCC 6260
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