STRINGSTRING
PGUG_05248 PGUG_05248 PGUG_00445 PGUG_00445 PGUG_00575 PGUG_00575 PGUG_00612 PGUG_00612 HTB2 HTB2 PGUG_01107 PGUG_01107 RPB1 RPB1 PGUG_01264 PGUG_01264 PGUG_01460 PGUG_01460 PGUG_01597 PGUG_01597 PGUG_01871 PGUG_01871 PGUG_01872 PGUG_01872 PGUG_01885 PGUG_01885 PGUG_01923 PGUG_01923 PGUG_02044 PGUG_02044 PGUG_02088 PGUG_02088 PGUG_02408 PGUG_02408 PGUG_02462 PGUG_02462 PGUG_02746 PGUG_02746 PGUG_02765 PGUG_02765 PGUG_02831 PGUG_02831 RPB2 RPB2 PGUG_02948 PGUG_02948 PGUG_03025 PGUG_03025 PGUG_03176 PGUG_03176 HTB1 HTB1 PGUG_03566 PGUG_03566 PGUG_03609 PGUG_03609 PGUG_03988 PGUG_03988 DBP2 DBP2 PGUG_04052 PGUG_04052 PGUG_04073 PGUG_04073 PGUG_04298 PGUG_04298 PGUG_04383 PGUG_04383 PGUG_04387 PGUG_04387 NCP1 NCP1 PGUG_04670 PGUG_04670 PGUG_04919 PGUG_04919 PGUG_04989 PGUG_04989 PGUG_05080 PGUG_05080 PGUG_05296 PGUG_05296 PGUG_05344 PGUG_05344 PGUG_05395 PGUG_05395 PGUG_05425 PGUG_05425
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PGUG_05248Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (123 aa)
PGUG_00445DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (112 aa)
PGUG_00575Serine/threonine-protein phosphatase. (529 aa)
PGUG_00612CYCLIN domain-containing protein; Belongs to the cyclin family. (383 aa)
HTB2Histone H2B.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (129 aa)
PGUG_01107DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (288 aa)
RPB1DNA-directed RNA polymerase II subunit RPB1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cl [...] (1579 aa)
PGUG_01264CYCLIN domain-containing protein; Belongs to the cyclin family. (292 aa)
PGUG_01460RPOL4c domain-containing protein. (188 aa)
PGUG_01597Striatin domain-containing protein. (597 aa)
PGUG_01871Uncharacterized protein. (153 aa)
PGUG_01872DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (148 aa)
PGUG_01885GATA-type domain-containing protein. (568 aa)
PGUG_01923Uncharacterized protein. (350 aa)
PGUG_02044Uncharacterized protein. (641 aa)
PGUG_02088Uncharacterized protein. (380 aa)
PGUG_02408Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (532 aa)
PGUG_02462Non-specific serine/threonine protein kinase. (734 aa)
PGUG_02746Protein kinase domain-containing protein. (1042 aa)
PGUG_02765DNA-directed RNA polymerases II 24 kDa polypeptide. (179 aa)
PGUG_02831Uncharacterized protein. (173 aa)
RPB2DNA-directed RNA polymerase II subunit RPB2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB2 is [...] (1236 aa)
PGUG_02948Protein kinase domain-containing protein. (786 aa)
PGUG_03025GH16 domain-containing protein. (314 aa)
PGUG_03176BHLH domain-containing protein. (242 aa)
HTB1Histone H2B.1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (129 aa)
PGUG_03566Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (506 aa)
PGUG_03609Fork-head domain-containing protein. (537 aa)
PGUG_03988Uncharacterized protein. (707 aa)
DBP2ATP-dependent RNA helicase DBP2; ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing. (554 aa)
PGUG_04052Uncharacterized protein. (72 aa)
PGUG_04073Histone acetyltransferase GCN5. (460 aa)
PGUG_04298TATA-box binding protein. (240 aa)
PGUG_04383Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1047 aa)
PGUG_04387Non-specific serine/threonine protein kinase. (638 aa)
NCP1NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (680 aa)
PGUG_04670HATPase_c domain-containing protein. (701 aa)
PGUG_04919Flavin_Reduct domain-containing protein. (231 aa)
PGUG_04989Uncharacterized protein. (73 aa)
PGUG_05080CS domain-containing protein. (234 aa)
PGUG_05296GATA-type domain-containing protein. (512 aa)
PGUG_05344Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (476 aa)
PGUG_05395RPOLD domain-containing protein. (305 aa)
PGUG_05425Uncharacterized protein. (158 aa)
Your Current Organism:
Meyerozyma guilliermondii
NCBI taxonomy Id: 294746
Other names: M. guilliermondii ATCC 6260, Meyerozyma guilliermondii ATCC 6260, Pichia guilliermondii ATCC 6260
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