STRINGSTRING
PGUG_00164 PGUG_00164 PGUG_00627 PGUG_00627 PGUG_00716 PGUG_00716 PGUG_00752 PGUG_00752 ADK1 ADK1 PGUG_00918 PGUG_00918 PGUG_00939 PGUG_00939 PGUG_00980 PGUG_00980 PGUG_01120 PGUG_01120 PGUG_01332 PGUG_01332 PGUG_01552 PGUG_01552 AAH1 AAH1 PGUG_01875 PGUG_01875 PGUG_01992 PGUG_01992 PGUG_02092 PGUG_02092 PGUG_02175 PGUG_02175 PGUG_02193 PGUG_02193 PGUG_02229 PGUG_02229 PGUG_02261 PGUG_02261 PGUG_02305 PGUG_02305 PGUG_02477 PGUG_02477 HAM1 HAM1 PGUG_02674 PGUG_02674 PGUG_02689 PGUG_02689 PGUG_02782 PGUG_02782 PGUG_02836 PGUG_02836 PGUG_02843 PGUG_02843 PGUG_02911 PGUG_02911 PGUG_02918 PGUG_02918 PGUG_02981 PGUG_02981 PGUG_02996 PGUG_02996 PGUG_03090 PGUG_03090 PGUG_03123 PGUG_03123 PGUG_03140 PGUG_03140 PGUG_03145 PGUG_03145 PGUG_03356 PGUG_03356 PGUG_03437 PGUG_03437 PGUG_03731 PGUG_03731 PGUG_03817 PGUG_03817 PGUG_03911 PGUG_03911 PGUG_04001 PGUG_04001 PGUG_04041 PGUG_04041 PGUG_04094 PGUG_04094 PGUG_04215 PGUG_04215 ADK2 ADK2 PGUG_04377 PGUG_04377 PGUG_04523 PGUG_04523 PGUG_04756 PGUG_04756 PGUG_04946 PGUG_04946 PGUG_05035 PGUG_05035 MET3 MET3 PGUG_05233 PGUG_05233 PGUG_05295 PGUG_05295 PGUG_05320 PGUG_05320
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PGUG_00164Amidohydro-rel domain-containing protein. (490 aa)
PGUG_00627Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (667 aa)
PGUG_00716Pyruvate kinase; Belongs to the pyruvate kinase family. (504 aa)
PGUG_00752PfkB domain-containing protein. (347 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (247 aa)
PGUG_00918Nucleoside diphosphate kinase. (151 aa)
PGUG_00939Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (481 aa)
PGUG_009803',5'-cyclic-nucleotide phosphodiesterase. (381 aa)
PGUG_01120SurE domain-containing protein. (338 aa)
PGUG_01332DHHA2 domain-containing protein. (400 aa)
PGUG_01552TR_THY domain-containing protein. (162 aa)
AAH1Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. (357 aa)
PGUG_01875Glutamine amidotransferase type-1 domain-containing protein. (1336 aa)
PGUG_01992Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (680 aa)
PGUG_02092Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family. (301 aa)
PGUG_02175Pribosyltran_N domain-containing protein. (412 aa)
PGUG_02193Uncharacterized protein. (336 aa)
PGUG_02229Uncharacterized protein. (608 aa)
PGUG_02261Nudix hydrolase domain-containing protein. (222 aa)
PGUG_02305SAICAR_synt domain-containing protein. (298 aa)
PGUG_02477Ribose-phosphate pyrophosphokinase 1. (320 aa)
HAM1Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (193 aa)
PGUG_02674Guanylate kinase-like domain-containing protein. (186 aa)
PGUG_02689PNP_UDP_1 domain-containing protein. (556 aa)
PGUG_02782Bis(5'-adenosyl)-triphosphatase. (178 aa)
PGUG_02836IMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation. (478 aa)
PGUG_02843Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (191 aa)
PGUG_02911Formyl_trans_N domain-containing protein. (210 aa)
PGUG_02918Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (863 aa)
PGUG_02981Uncharacterized protein. (418 aa)
PGUG_02996Pribosyltran domain-containing protein. (213 aa)
PGUG_03090SurE domain-containing protein. (320 aa)
PGUG_03123ATP-grasp domain-containing protein. (814 aa)
PGUG_03140Amidophosphoribosyltransferase. (530 aa)
PGUG_03145Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Belongs to the adenylosuccinate synthetase family. (426 aa)
PGUG_03356Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (199 aa)
PGUG_03437ATP_transf domain-containing protein. (314 aa)
PGUG_03731Pribosyltran_N domain-containing protein. (472 aa)
PGUG_03817Bifunctional purine biosynthesis protein ADE17. (590 aa)
PGUG_03911Uncharacterized protein. (1475 aa)
PGUG_04001Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (521 aa)
PGUG_04041GMP synthase. (529 aa)
PGUG_04094Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (814 aa)
PGUG_04215Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (521 aa)
ADK2GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (230 aa)
PGUG_04377Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (568 aa)
PGUG_04523Uncharacterized protein. (206 aa)
PGUG_04756Phosphodiesterase. (605 aa)
PGUG_04946Pribosyltran domain-containing protein. (186 aa)
PGUG_05035A_deaminase domain-containing protein. (819 aa)
MET3Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. Belongs to the sulfate adenylyltransferase family. (523 aa)
PGUG_05233Pribosyltran_N domain-containing protein. (323 aa)
PGUG_05295Uncharacterized protein; Belongs to the phosphohexose mutase family. (554 aa)
PGUG_05320Uncharacterized protein. (649 aa)
Your Current Organism:
Meyerozyma guilliermondii
NCBI taxonomy Id: 294746
Other names: M. guilliermondii ATCC 6260, Meyerozyma guilliermondii ATCC 6260, Pichia guilliermondii ATCC 6260
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