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PGUG_00102 PGUG_00102 PGUG_00150 PGUG_00150 PGUG_00228 PGUG_00228 PGUG_00294 PGUG_00294 PGUG_00307 PGUG_00307 PGUG_00480 PGUG_00480 PGUG_00504 PGUG_00504 PGUG_00645 PGUG_00645 PGUG_00646 PGUG_00646 PGUG_00716 PGUG_00716 PGUG_00881 PGUG_00881 PGUG_00926 PGUG_00926 PGUG_00951 PGUG_00951 PGUG_00963 PGUG_00963 PGUG_00965 PGUG_00965 PGUG_01180 PGUG_01180 PGUG_01193 PGUG_01193 PGUG_01217 PGUG_01217 PGUG_01239 PGUG_01239 PGUG_01282 PGUG_01282 PGUG_01317 PGUG_01317 PGUG_01341 PGUG_01341 PGUG_01379 PGUG_01379 PGUG_01405 PGUG_01405 PGUG_01486 PGUG_01486 PGUG_01489 PGUG_01489 PGUG_01501 PGUG_01501 PGUG_01503 PGUG_01503 PGUG_01716 PGUG_01716 PGUG_01850 PGUG_01850 RKI1 RKI1 PGUG_02164 PGUG_02164 PGUG_02175 PGUG_02175 PGUG_02270 PGUG_02270 PGUG_02272 PGUG_02272 PGUG_02477 PGUG_02477 PGUG_02540 PGUG_02540 PGUG_02577 PGUG_02577 PGUG_02579 PGUG_02579 PGUG_02601 PGUG_02601 PGUG_02603 PGUG_02603 PGUG_02641 PGUG_02641 PGUG_02787 PGUG_02787 PGUG_02805 PGUG_02805 PGUG_02856 PGUG_02856 PGUG_02909 PGUG_02909 PGUG_02910 PGUG_02910 PGUG_03003 PGUG_03003 PGUG_03026 PGUG_03026 PGUG_03146 PGUG_03146 PGUG_03168 PGUG_03168 PGUG_03274 PGUG_03274 PGUG_03289 PGUG_03289 PGUG_03290 PGUG_03290 PGUG_03327 PGUG_03327 PGUG_03460 PGUG_03460 PGUG_03476 PGUG_03476 PGUG_03485 PGUG_03485 PGUG_03513 PGUG_03513 PGUG_03524 PGUG_03524 PGUG_03564 PGUG_03564 PGUG_03659 PGUG_03659 PGUG_03724 PGUG_03724 PGUG_03731 PGUG_03731 PGUG_03757 PGUG_03757 PGUG_03763 PGUG_03763 PGUG_03808 PGUG_03808 PGUG_03925 PGUG_03925 PGUG_03973 PGUG_03973 PGUG_04024 PGUG_04024 PGUG_04072 PGUG_04072 PGUG_04080 PGUG_04080 PGUG_04175 PGUG_04175 PGUG_04316 PGUG_04316 PGUG_04335 PGUG_04335 PGUG_04391 PGUG_04391 PGUG_04469 PGUG_04469 PGUG_04504 PGUG_04504 PGUG_04596 PGUG_04596 PGUG_04648 PGUG_04648 PGUG_04679 PGUG_04679 PGUG_04804 PGUG_04804 PGUG_04807 PGUG_04807 PGUG_04813 PGUG_04813 PGUG_04868 PGUG_04868 PGUG_04906 PGUG_04906 PGUG_04966 PGUG_04966 PGUG_05024 PGUG_05024 PGUG_05084 PGUG_05084 PGUG_05161 PGUG_05161 PGUG_05233 PGUG_05233 PGUG_05240 PGUG_05240 PGUG_05294 PGUG_05294 PGUG_05360 PGUG_05360 PGUG_05465 PGUG_05465 PGUG_05561 PGUG_05561 PGUG_05581 PGUG_05581 PGUG_05602 PGUG_05602 PGUG_05611 PGUG_05611 PGUG_05751 PGUG_05751
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PGUG_00102Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (779 aa)
PGUG_00150Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (474 aa)
PGUG_00228Uncharacterized protein. (594 aa)
PGUG_00294Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (322 aa)
PGUG_00307Citrate synthase; Belongs to the citrate synthase family. (395 aa)
PGUG_00480Phosphotransferase. (536 aa)
PGUG_00504Succinate dehydrogenase [ubiquinone] cytochrome b small subunit. (164 aa)
PGUG_00645Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (703 aa)
PGUG_00646Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (706 aa)
PGUG_00716Pyruvate kinase; Belongs to the pyruvate kinase family. (504 aa)
PGUG_00881Uncharacterized protein. (625 aa)
PGUG_00926Glucose-6-phosphate isomerase; Belongs to the GPI family. (551 aa)
PGUG_00951Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (232 aa)
PGUG_00963Lyase_1 domain-containing protein. (328 aa)
PGUG_00965Phosphotransferase. (481 aa)
PGUG_01180Dihydrolipoyl dehydrogenase. (493 aa)
PGUG_01193Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (725 aa)
PGUG_01217TRANSKETOLASE_1 domain-containing protein. (683 aa)
PGUG_01239Phosphoenolpyruvate carboxykinase. (610 aa)
PGUG_01282Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (677 aa)
PGUG_01317Glyceraldehyde-3-phosphate dehydrogenase. (335 aa)
PGUG_01341Uncharacterized protein. (487 aa)
PGUG_01379Uncharacterized protein. (437 aa)
PGUG_01405Triosephosphate isomerase. (248 aa)
PGUG_01486Gluconokinase; Belongs to the gluconokinase GntK/GntV family. (186 aa)
PGUG_01489Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
PGUG_01501Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (642 aa)
PGUG_01503Malate dehydrogenase. (349 aa)
PGUG_01716D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (464 aa)
PGUG_01850Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (485 aa)
RKI1Ribose-5-phosphate isomerase. (247 aa)
PGUG_02164Aminotran_1_2 domain-containing protein. (502 aa)
PGUG_02175Pribosyltran_N domain-containing protein. (412 aa)
PGUG_02270Threonine dehydratase. (583 aa)
PGUG_02272Aminotran_5 domain-containing protein. (296 aa)
PGUG_02477Ribose-phosphate pyrophosphokinase 1. (320 aa)
PGUG_02540Malate dehydrogenase. (336 aa)
PGUG_02577Aminotran_1_2 domain-containing protein. (402 aa)
PGUG_02579Malate dehydrogenase. (332 aa)
PGUG_02601Phosphotransferase. (469 aa)
PGUG_02603Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (469 aa)
PGUG_02641S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (290 aa)
PGUG_02787Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (404 aa)
PGUG_02805Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (409 aa)
PGUG_02856Uncharacterized protein. (292 aa)
PGUG_02909S-(Hydroxymethyl)glutathione dehydrogenase. (254 aa)
PGUG_02910Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (365 aa)
PGUG_03003Uncharacterized protein. (302 aa)
PGUG_03026ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (984 aa)
PGUG_03146Iso_dh domain-containing protein. (196 aa)
PGUG_03168PALP domain-containing protein. (427 aa)
PGUG_03274Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (382 aa)
PGUG_03289Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (257 aa)
PGUG_03290Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (379 aa)
PGUG_03327Malate synthase; Belongs to the malate synthase family. (551 aa)
PGUG_03460Transket_pyr domain-containing protein. (997 aa)
PGUG_03476Lipoyl-binding domain-containing protein. (446 aa)
PGUG_03485Aspartate aminotransferase. (421 aa)
PGUG_03513Uncharacterized protein. (351 aa)
PGUG_03524MaoC-like domain-containing protein. (1010 aa)
PGUG_035646-phosphogluconolactonase-like protein; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily. (310 aa)
PGUG_03659Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (437 aa)
PGUG_03724Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (501 aa)
PGUG_03731Pribosyltran_N domain-containing protein. (472 aa)
PGUG_03757Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1180 aa)
PGUG_03763Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (407 aa)
PGUG_03808Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (416 aa)
PGUG_03925Aminotran_1_2 domain-containing protein. (512 aa)
PGUG_03973FBPase domain-containing protein; Belongs to the FBPase class 1 family. (344 aa)
PGUG_04024Aminotran_5 domain-containing protein. (406 aa)
PGUG_040726-phosphogluconolactonase-like protein; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily. (251 aa)
PGUG_04080Succinate-CoA ligase subunit beta. (327 aa)
PGUG_04175PALP domain-containing protein. (221 aa)
PGUG_043163-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (498 aa)
PGUG_04335Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (396 aa)
PGUG_04391Enolase 1. (439 aa)
PGUG_04469Succinate dehydrogenase [ubiquinone] cytochrome b small subunit. (192 aa)
PGUG_04504FMN hydroxy acid dehydrogenase domain-containing protein. (378 aa)
PGUG_04596Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
PGUG_04648Uncharacterized protein. (355 aa)
PGUG_04679ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (952 aa)
PGUG_04804Isocitrate lyase. (551 aa)
PGUG_04807Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (252 aa)
PGUG_04813Acetyl-coenzyme A synthetase. (514 aa)
PGUG_04868Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1023 aa)
PGUG_04906PALP domain-containing protein. (319 aa)
PGUG_04966PALP domain-containing protein. (355 aa)
PGUG_05024Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (287 aa)
PGUG_050846-phosphogluconate dehydrogenase, decarboxylating; Belongs to the 6-phosphogluconate dehydrogenase family. (409 aa)
PGUG_05161Uncharacterized protein. (426 aa)
PGUG_05233Pribosyltran_N domain-containing protein. (323 aa)
PGUG_05240Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (291 aa)
PGUG_05294Aminotran_1_2 domain-containing protein. (426 aa)
PGUG_05360Aldedh domain-containing protein. (351 aa)
PGUG_05465Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (641 aa)
PGUG_05561Acetyl-coenzyme A synthetase. (670 aa)
PGUG_05581Catalase domain-containing protein. (555 aa)
PGUG_05602Lipoyl-binding domain-containing protein. (136 aa)
PGUG_05611Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
PGUG_05751Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (393 aa)
Your Current Organism:
Meyerozyma guilliermondii
NCBI taxonomy Id: 294746
Other names: M. guilliermondii ATCC 6260, Meyerozyma guilliermondii ATCC 6260, Pichia guilliermondii ATCC 6260
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