STRINGSTRING
CNBG_1048 CNBG_1048 CNBG_0057 CNBG_0057 CNBG_0062 CNBG_0062 CNBG_1208 CNBG_1208 CNBG_0712 CNBG_0712 CNBG_2270 CNBG_2270 CNBG_3575 CNBG_3575 CNBG_4189 CNBG_4189 CNBG_5535 CNBG_5535 CNBG_5287 CNBG_5287 CNBG_5712 CNBG_5712 CNBG_6182 CNBG_6182 CNBG_0884 CNBG_0884 CNBG_3034 CNBG_3034 CNBG_4178 CNBG_4178 CNBG_5074 CNBG_5074 CNBG_1521 CNBG_1521 CNBG_2331 CNBG_2331 CNBG_3051 CNBG_3051 CNBG_5421 CNBG_5421 CNBG_6106 CNBG_6106 CNBG_9587 CNBG_9587 CNBG_9075 CNBG_9075 CNBG_9174 CNBG_9174
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CNBG_1048DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (922 aa)
CNBG_0057ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (914 aa)
CNBG_0062DNA replication regulator DPB11. (863 aa)
CNBG_1208DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (362 aa)
CNBG_0712Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (613 aa)
CNBG_2270RecQ-mediated genome instability protein 1. (455 aa)
CNBG_3575Uncharacterized protein. (253 aa)
CNBG_4189Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (727 aa)
CNBG_5535Uncharacterized protein. (217 aa)
CNBG_5287DNA replication ATP-dependent helicase Dna2. (1416 aa)
CNBG_5712Checkpoint protein; Belongs to the HUS1 family. (268 aa)
CNBG_6182Exonuclease 1. (802 aa)
CNBG_0884Replication factor A2. (266 aa)
CNBG_3034Signal transducer. (929 aa)
CNBG_4178Cell cycle checkpoint control protein RAD9A. (631 aa)
CNBG_5074DNA repair protein RAD50. (1231 aa)
CNBG_1521RAD51-like protein 2. (283 aa)
CNBG_2331Breast cancer 2 susceptibility protein. (497 aa)
CNBG_3051RAD57 protein. (590 aa)
CNBG_5421Cell cycle checkpoint protein. (305 aa)
CNBG_6106DNA repair and recombination protein RAD52. (519 aa)
CNBG_9587Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family. (2243 aa)
CNBG_9075BRCT domain-containing protein. (1362 aa)
CNBG_9174Serine/threonine-protein kinase TEL1; Belongs to the PI3/PI4-kinase family. (2502 aa)
Your Current Organism:
Cryptococcus gattii
NCBI taxonomy Id: 294750
Other names: C. gattii VGII R265, Cryptococcus bacillisporus R265, Cryptococcus bacillisporus VGII R265, Cryptococcus deuterogattii R265, Cryptococcus gattii R265, Cryptococcus gattii VGII R265, Cryptococcus neoformans R265
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.