(31 nodes) Neuronal System network (Cryptococcus gattii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Your Input:
	CNBG_0408	Peptidase. (872 aa)
	CNBG_1346	cAMP-dependent protein kinase regulatory subunit. (482 aa)
	CNBG_0191	CAMKK protein kinase. (1060 aa)
	CNBG_0011	Ion_trans domain-containing protein. (554 aa)
	CNBG_6204	Uncharacterized protein. (1180 aa)
	CNBG_5459	Potassium channel protein; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (810 aa)
	CNBG_4379	CAMKK/CAMKK-META protein kinase. (480 aa)
	CNBG_1454	Glutamine synthetase. (358 aa)
	CNBG_0649	Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. (495 aa)
	CNBG_6185	Uncharacterized protein. (302 aa)
	CNBG_5781	Uncharacterized protein. (276 aa)
	CNBG_5595	Solute carrier family 32 (Vesicular inhibitory amino acid transporter). (524 aa)
	CNBG_4577	Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. (520 aa)
	CNBG_4012	MFS domain-containing protein. (502 aa)
	CNBG_2577	Uncharacterized protein. (147 aa)
	CNBG_2835	Voltage-gated potassium channel beta-2 subunit. (349 aa)
	CNBG_1937	Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. (330 aa)
	CNBG_0647	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (491 aa)
	CNBG_0607	Succinate-semialdehyde dehydrogenase (NADP+); Belongs to the aldehyde dehydrogenase family. (501 aa)
	CNBG_1380	Carnitine O-acetyltransferase. (630 aa)
	CNBG_1508	AGC/PKA protein kinase. (516 aa)
	CNBG_1220	Glutamine synthetase; Belongs to the glutamine synthetase family. (454 aa)
	CNBG_2086	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (1035 aa)
	CNBG_3404	Chaperone DNAJ. (268 aa)
	CNBG_2849	O-methyltransferase. (261 aa)
	CNBG_1834	Uncharacterized protein. (697 aa)
	URM1	Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target pr [...] (144 aa)
	CNBG_4401	2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (332 aa)
	CNBG_4075	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (501 aa)
	CNBG_3985	Homoserine O-acetyltransferase. (456 aa)
	CNBG_2596	Succinate-semialdehyde dehydrogenase (NADP+); Belongs to the aldehyde dehydrogenase family. (501 aa)

Your Current Organism:

Cryptococcus gattii

NCBI taxonomy Id: 294750
Other names: C. gattii VGII R265, Cryptococcus bacillisporus R265, Cryptococcus bacillisporus VGII R265, Cryptococcus deuterogattii R265, Cryptococcus gattii R265, Cryptococcus gattii VGII R265, Cryptococcus neoformans R265

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CNBG_0011	CNBG_1508	A0A095E9C1	A0A095C4C2	Ion_trans domain-containing protein.	AGC/PKA protein kinase.	0.650
CNBG_0011	CNBG_1834	A0A095E9C1	A0A095D3W5	Ion_trans domain-containing protein.	Uncharacterized protein.	0.448
CNBG_0011	CNBG_2835	A0A095E9C1	A0A095C915	Ion_trans domain-containing protein.	Voltage-gated potassium channel beta-2 subunit.	0.830
CNBG_0011	CNBG_4401	A0A095E9C1	A0A095ENH2	Ion_trans domain-containing protein.	2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.	0.650
CNBG_0011	CNBG_5459	A0A095E9C1	A0A095DG06	Ion_trans domain-containing protein.	Potassium channel protein; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.	0.501
CNBG_0011	CNBG_6204	A0A095E9C1	A0A095DIB1	Ion_trans domain-containing protein.	Uncharacterized protein.	0.496
CNBG_0408	CNBG_2086	A0A095C0U5	A0A095EFT7	Peptidase.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.481
CNBG_0408	CNBG_4012	A0A095C0U5	A0A095CBM0	Peptidase.	MFS domain-containing protein.	0.437
CNBG_0607	CNBG_0647	A0A095C4P0	A0A095C4T1	Succinate-semialdehyde dehydrogenase (NADP+); Belongs to the aldehyde dehydrogenase family.	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.930
CNBG_0607	CNBG_1220	A0A095C4P0	A0A095C462	Succinate-semialdehyde dehydrogenase (NADP+); Belongs to the aldehyde dehydrogenase family.	Glutamine synthetase; Belongs to the glutamine synthetase family.	0.543
CNBG_0607	CNBG_1454	A0A095C4P0	A0A095D2M1	Succinate-semialdehyde dehydrogenase (NADP+); Belongs to the aldehyde dehydrogenase family.	Glutamine synthetase.	0.543
CNBG_0607	CNBG_2596	A0A095C4P0	A0A095EHF2	Succinate-semialdehyde dehydrogenase (NADP+); Belongs to the aldehyde dehydrogenase family.	Succinate-semialdehyde dehydrogenase (NADP+); Belongs to the aldehyde dehydrogenase family.	0.874
CNBG_0607	CNBG_4075	A0A095C4P0	A0A095ELI9	Succinate-semialdehyde dehydrogenase (NADP+); Belongs to the aldehyde dehydrogenase family.	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.930
CNBG_0647	CNBG_0607	A0A095C4T1	A0A095C4P0	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Succinate-semialdehyde dehydrogenase (NADP+); Belongs to the aldehyde dehydrogenase family.	0.930
CNBG_0647	CNBG_0649	A0A095C4T1	A0A095CZW6	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family.	0.915
CNBG_0647	CNBG_1220	A0A095C4T1	A0A095C462	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Glutamine synthetase; Belongs to the glutamine synthetase family.	0.596
CNBG_0647	CNBG_1346	A0A095C4T1	A0A095EDI7	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	cAMP-dependent protein kinase regulatory subunit.	0.604
CNBG_0647	CNBG_1454	A0A095C4T1	A0A095D2M1	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Glutamine synthetase.	0.596
CNBG_0647	CNBG_1937	A0A095C4T1	A0A095C8Z2	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family.	0.915
CNBG_0647	CNBG_2596	A0A095C4T1	A0A095EHF2	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Succinate-semialdehyde dehydrogenase (NADP+); Belongs to the aldehyde dehydrogenase family.	0.930

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