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hyb0 hyb0 hybA hybA hybC hybC ywrO ywrO yedZ yedZ cybC cybC CNG32744.1 CNG32744.1 frdA frdA b4153 b4153 fldA fldA sdhC sdhC sdhA sdhA sdhB sdhB cydA_2 cydA_2 ybgT ybgT cyoD cyoD cyoC cyoC cyoB cyoB cyoA cyoA CNG14504.1 CNG14504.1 mioC_1 mioC_1 dorA dorA CNG11435.1 CNG11435.1 isiB isiB norV norV napC napC napA napA fdx_2 fdx_2 yceJ yceJ torA torA dld dld CNF85049.1 CNF85049.1 hydN_1 hydN_1 hyfI hyfI hyfG hyfG hyfF hyfF hyfE hyfE hyfD hyfD hyfC hyfC hyfB hyfB nqr2 nqr2 CNF75073.1 CNF75073.1 cydA_1 cydA_1 etfB etfB etfA etfA dmsC1 dmsC1 dmsA1_1 dmsA1_1 rnfE rnfE rnfG rnfG rnfD rnfD rnfC_1 rnfC_1 rnfB rnfB rnfA rnfA acpD acpD nifJ nifJ CNF38845.1 CNF38845.1 dsbB dsbB hyfA hyfA fdoI fdoI ndhC ndhC nuoB nuoB nuoD nuoD nuoE nuoE nuoF nuoF nuoG nuoG nuoJ nuoJ nuoK nuoK nuoL nuoL nuoM nuoM nuoN nuoN CNG83407.1 CNG83407.1 yodB yodB dmsC2 dmsC2 dmsA2 dmsA2 hydN_2 hydN_2 dsbD dsbD grxA grxA ycbX_2 ycbX_2 nqrE1 nqrE1 nqr6 nqr6
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hyb0Hydrogenase 2 small subunit. (371 aa)
hybAHydrogenase 2 protein HybA. (346 aa)
hybCHydrogenase 2 large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (564 aa)
ywrOGlutathione-regulated potassium-efflux system ancillary protein KefG; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB. (183 aa)
yedZPutative sulfite oxidase subunit YedZ; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subuni [...] (199 aa)
cybCPutative cytochrome. (128 aa)
CNG32744.1Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (104 aa)
frdASuccinate dehydrogenase flavoprotein subunit. (601 aa)
b4153Fumarate reductase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (244 aa)
fldAFlavodoxin FldA; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (175 aa)
sdhCSuccinate dehydrogenase cytochrome b556 large membrane subunit. (94 aa)
sdhASuccinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa)
sdhBSuccinate dehydrogenase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (238 aa)
cydA_2Cytochrome D ubiquinol oxidase subunit I. (522 aa)
ybgTCyd operon protein YbgT. (45 aa)
cyoDCytochrome O ubiquinol oxidase subunit CyoD. (115 aa)
cyoCCytochrome o ubiquinol oxidase subunit III. (204 aa)
cyoBCytochrome O ubiquinol oxidase subunit I; Belongs to the heme-copper respiratory oxidase family. (663 aa)
cyoACytochrome o ubiquinol oxidase subunit II. (318 aa)
CNG14504.1Putative cytochrome. (104 aa)
mioC_1Flavodoxin. (149 aa)
dorAPutative biotin sulfoxide reductas2; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (753 aa)
CNG11435.1Uncharacterised protein. (216 aa)
isiBFlavodoxin FldB; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (172 aa)
norVAnaerobic nitric oxide reductase flavorubredoxin. (480 aa)
napCCytochrome c-type protein NapC. (199 aa)
napANitrate reductase catalytic subunit; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. (831 aa)
fdx_2Ferredoxin. (111 aa)
yceJCytochrome b561 family protein. (184 aa)
torAPutative molybdopterin-containing oxidoreductase. (815 aa)
dldD-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. (569 aa)
CNF85049.1Putative inner membrane protein. (388 aa)
hydN_14Fe-4S ferredoxin. (180 aa)
hyfIHydrogenase-4 subunit I. (268 aa)
hyfGHydrogenase-4 subunit G. (597 aa)
hyfFHydrogenase 4 subunit F. (543 aa)
hyfEHydrogenase 4 membrane subunit. (216 aa)
hyfDHydrogenase 4 subunit D. (495 aa)
hyfCHydrogenase-4 subunit C. (317 aa)
hyfBHydrogenase 4 subunit B. (675 aa)
nqr2Na(+)-translocating NADH-quinone reductase subunit B; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. (413 aa)
CNF75073.1Putative cytochrome. (104 aa)
cydA_1Putative cytochrome oxidase subunit. (479 aa)
etfBElectron transfer flavoprotein small subunit. (254 aa)
etfAElectron transfer flavoprotein large subunit. (317 aa)
dmsC1Anaerobic dimethyl sulfoxide reductase chain C. (286 aa)
dmsA1_1Anaerobic dimethyl sulfoxide reductase chain A; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (816 aa)
rnfEElectron transport complex protein RsxE; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. (233 aa)
rnfGElectron transport complex protein RnfG; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family. (209 aa)
rnfDElectron transport complex protein RnfD; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family. (345 aa)
rnfC_1Electron transport complex protein RnfC; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. (695 aa)
rnfBElectron transport complex protein RnfB; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. (207 aa)
rnfANa(+)-translocating NADH-quinone reductase subunit E; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. (193 aa)
acpDAzoreductase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family. (201 aa)
nifJPutative pyruvate-flavodoxin oxidoreductase. (1177 aa)
CNF38845.1Protein of uncharacterised function (DUF2502). (180 aa)
dsbBPeriplasmic thiol:disulfide oxidoreductase DsbB%2Crequired for DsbA reoxidation; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. (176 aa)
hyfAFormate hydrogenlyase subunit 2. (213 aa)
fdoIFormate dehydrogenase-O subunit gamma. (216 aa)
ndhCNADH dehydrogenase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (152 aa)
nuoBNADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (225 aa)
nuoDBifunctional NADH:ubiquinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. (598 aa)
nuoENADH dehydrogenase subunit E. (187 aa)
nuoFNADH dehydrogenase I subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (455 aa)
nuoGNADH dehydrogenase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (914 aa)
nuoJNADH dehydrogenase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (181 aa)
nuoKNADH dehydrogenase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (100 aa)
nuoLNADH dehydrogenase subunit L. (614 aa)
nuoMNADH dehydrogenase subunit M. (507 aa)
nuoNNADH:ubiquinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (485 aa)
CNG83407.1Protein of uncharacterised function (DUF2502). (150 aa)
yodBPutative B-type cytochrome. (174 aa)
dmsC2Anaerobic dimethyl sulfoxide reductase subunit B. (258 aa)
dmsA2Dimethyl sulfoxide reductase chain A protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (807 aa)
hydN_24Fe-4S ferredoxin. (173 aa)
dsbDThiol:disulfide interchange protein; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. (582 aa)
grxAGlutaredoxin. (87 aa)
ycbX_22Fe-2S ferredoxin YfaE. (110 aa)
nqrE1Na(+)-translocating NADH-quinone reductase subunit E; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family. (198 aa)
nqr6Na(+)-translocating NADH-quinone reductase subunit F; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway. (407 aa)
Your Current Organism:
Yersinia frederiksenii
NCBI taxonomy Id: 29484
Other names: ATCC 33641, CCUG 11293, CIP 80.29, DSM 18490, NCTC 11470, Y. frederiksenii, strain 6175
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