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| | tmk | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (213 aa) |
| | cobU | Bifunctional adenosylcobalamin biosynthesis protein CobU; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (181 aa) |
| | CH64_1021 | Fructosamine kinase family protein. (297 aa) |
| | ycaR | Trm112p-like family protein; Belongs to the UPF0434 family. (60 aa) |
| | lpxK | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (328 aa) |
| | cmk | Cmk: cytidylate kinase. (230 aa) |
| | ttrS | His Kinase A domain protein. (579 aa) |
| | pfkB | pfkB: 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. (312 aa) |
| | bglF | EIIB_glc: PTS system, glucose-like IIB component domain protein. (509 aa) |
| | rcsD | Hpt domain protein; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. (897 aa) |
| | gntK_2 | Therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family protein. (176 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa) |
| | gmuB | PTS system, Lactose/Cellobiose specific IIB subunit. (104 aa) |
| | pleD | GGDEF: diguanylate cyclase domain protein. (335 aa) |
| | CH64_1286 | 2-keto-3-deoxy-galactonokinase family protein. (298 aa) |
| | ascF | EIIB_glc: PTS system, glucose-like IIB component domain protein. (483 aa) |
| | ypdA | 5TMR of 5TMR-LYT family protein. (549 aa) |
| | glk | Glk: glucokinase; Belongs to the bacterial glucokinase family. (323 aa) |
| | pduX | GHMP kinase N terminal domain protein. (286 aa) |
| | ptsI | Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (575 aa) |
| | cpxA_1 | HAMP domain protein. (452 aa) |
| | nanK | N-acetylmannosamine kinase; Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P; Belongs to the ROK (NagC/XylR) family. NanK subfamily. (290 aa) |
| | ppk1 | Polyphosphate kinase 1; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (687 aa) |
| | baeS_2 | HAMP domain protein. (458 aa) |
| | yegS | Lipid kinase YegS; Probably phosphorylates lipids; the in vivo substrate is unknown; Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily. (299 aa) |
| | thiD | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. (266 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (142 aa) |
| | bvgS | Hpt domain protein. (1284 aa) |
| | glrK | HAMP domain protein. (478 aa) |
| | ppnK | ATP-NAD kinase family protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (255 aa) |
| | CH64_154 | Putative thymidylate kinase. (174 aa) |
| | chbB | N,N'-diacetylchitobiose-specific phosphotransferase enzyme IIB component. (105 aa) |
| | nreB | Histidine kinase family protein. (518 aa) |
| | dpiB | Sensor histidine kinase DpiB. (534 aa) |
| | pyrH | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (248 aa) |
| | citG | citrate_citG: triphosphoribosyl-dephospho-CoA synthase CitG. (297 aa) |
| | ptsP | PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase; Belongs to the PEP-utilizing enzyme family. (746 aa) |
| | fbaA | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (359 aa) |
| | pgk | Phosphoglycerate kinase family protein; Belongs to the phosphoglycerate kinase family. (387 aa) |
| | baeS_1 | HAMP domain protein. (476 aa) |
| | cheA | Signal transducing histidine kinase, homodimeric domain protein. (679 aa) |
| | rfaE1 | Bifunctional protein RfaE, domain I; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (476 aa) |
| | murP | Phosphotransferase system, EIIB family protein. (483 aa) |
| | arcB | Sensory box protein. (778 aa) |
| | treP | PTS-IIBC-Tre: PTS system, trehalose-specific IIBC component. (471 aa) |
| | rnk | Hypothetical protein; May act as an anti-Gre factor; Belongs to the Rnk family. (136 aa) |
| | dgkA | Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (123 aa) |
| | pgi | Glucose-6-phosphate isomerase; Belongs to the GPI family. (548 aa) |
| | lysC | Asp_kin_monofn: aspartate kinase, monofunctional class; Belongs to the aspartokinase family. (436 aa) |
| | aceK | Isocitrate dehydrogenase kinase/phosphatase family protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. (575 aa) |
| | prk | Phosphoribulokinase / Uridine kinase family protein. (289 aa) |
| | aroK | Shikimate kinase 1; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (173 aa) |
| | envZ | HAMP domain protein. (453 aa) |
| | yehU | Histidine kinase family protein. (565 aa) |
| | gntK_1 | Therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family protein. (169 aa) |
| | iolC | myo_inos_iolC_N: 5-dehydro-2-deoxygluconokinase. (639 aa) |
| | kdgK | pfkB carbohydrate kinase family protein. (314 aa) |
| | uhpB | Histidine kinase family protein. (509 aa) |
| | xylB | xylB: xylulokinase. (484 aa) |
| | fixL | His Kinase A domain protein. (449 aa) |
| | rbsK | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (308 aa) |
| | rdoA | Phosphotransferase enzyme family protein; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response. (328 aa) |
| | glnL | Nitrogen regulation protein NR. (349 aa) |
| | spoT | Bifunctional (p)ppGpp synthase/hydrolase SpoT; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (700 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (207 aa) |
| | gpmI | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (515 aa) |
| | cpxA | Sensor protein CpxA. (458 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (327 aa) |
| | tpiA | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (255 aa) |
| | glpK | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (507 aa) |
| | metL | Asp_kinase: aspartate kinase domain protein; In the C-terminal section; belongs to the homoserine dehydrogenase family. (811 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate. (257 aa) |
| | wzzE | Lipopolysaccharide biosynthesis protein wzzE; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family. (353 aa) |
| | ubiB | 2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. (543 aa) |
| | hemG | Flavodoxin domain protein. (177 aa) |
| | coaA | panK_bact: pantothenate kinase. (316 aa) |
| | torS | Hpt domain protein. (927 aa) |
| | glxK | Glycerate kinase family protein; Belongs to the glycerate kinase type-1 family. (382 aa) |
| | basS | HAMP domain protein. (353 aa) |
| | dcuS | PAS fold family protein. (563 aa) |
| | evgS | Sensor protein evgS. (1207 aa) |
| | lsrF | Hypothetical protein; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5- phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA; Belongs to the DeoC/FbaB aldolase family. (291 aa) |
| | lsrK | Autoinducer 2 kinase LsrK; Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position. (530 aa) |
| | dhaK | dhaK1: dihydroxyacetone kinase, DhaK subunit. (356 aa) |
| | dhaL | dha_L_ycgS: dihydroxyacetone kinase, L subunit. (210 aa) |
| | dhaM | PTS-dependent dihydroxyacetone kinase, phosphotransferase subunit dhaM; Belongs to the PEP-utilizing enzyme family. (480 aa) |
| | scrA | PTS-II-BC-sucr: PTS system, sucrose-specific IIBC component. (456 aa) |
| | scrK | pfkB carbohydrate kinase family protein; Belongs to the carbohydrate kinase PfkB family. (310 aa) |
| | nadR | Trifunctional NAD biosynthesis/regulator protein NadR. (422 aa) |
| | gpmB | Histidine phosphatase super family protein; Belongs to the phosphoglycerate mutase family. GpmB subfamily. (215 aa) |
| | thrA | Asp_kinase: aspartate kinase domain protein; In the C-terminal section; belongs to the homoserine dehydrogenase family. (819 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (309 aa) |
| | ribF | ribF: riboflavin biosynthesis protein RibF; Belongs to the ribF family. (312 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (206 aa) |
| | aceE | Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (887 aa) |
| | aceF | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (625 aa) |
| | narX | Nitrate/nitrite sensor protein narX. (593 aa) |
| | folK | folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase. (159 aa) |
| | barA | HAMP domain protein. (920 aa) |
| | relA | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (744 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (431 aa) |
| | cysC | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (221 aa) |
| | glpK_1 | Hypothetical protein; FGGY family of carbohydrate kinase, N-terminal domain protein. (507 aa) |
| | mtnK | S-methyl-5-thioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. (399 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (367 aa) |
| | aroL | Shikimate kinase 2; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate. (174 aa) |
| | mak | Glucokinase family protein. (303 aa) |
| | phoR | phoR_proteo: phosphate regulon sensor kinase PhoR. (438 aa) |
| | thiL | Thiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (329 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (214 aa) |
| | gsk | Inosine-guanosine kinase. (434 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (315 aa) |
| | ispE | 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily. (296 aa) |
| | CH64_3692 | Hypothetical protein. (164 aa) |
| | nagE | PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component. (676 aa) |
| | CH64_375 | Tetratricopeptide repeat family protein. (269 aa) |
| | kdpD | Universal stress family protein. (895 aa) |
| | gpmA | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (250 aa) |
| | galK | Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (383 aa) |
| | pyk | Pyruv_kin: pyruvate kinase; Belongs to the pyruvate kinase family. (480 aa) |
| | udk | Udk: uridine kinase. (213 aa) |
| | CH64_447 | Hypothetical protein; prkA serine kinase C-terminal domain protein. (644 aa) |
| | selD | Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. (348 aa) |
| | tdk | Thymidine kinase family protein. (199 aa) |
| | ydgK | Inner membrane protein ydgK. (147 aa) |
| | araB | L-ribulokinase: ribulokinase. (569 aa) |
| | malX | pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component domain protein. (536 aa) |
| | rbsK-2 | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (309 aa) |
| | rstB | HAMP domain protein. (438 aa) |
| | pdxY | Pyridoxal kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. (302 aa) |
| | pyk-2 | Pyruv_kin: pyruvate kinase; Belongs to the pyruvate kinase family. (470 aa) |
| | ppsA | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (793 aa) |
| | ydiA | Putative phosphotransferase ydiA; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. (273 aa) |
| | yniA | Fructosamine kinase family protein. (289 aa) |
| | argK | Lao: LAO/AO transport system ATPase. (331 aa) |
| | manX | PTS system mannose-specific EIIAB component. (324 aa) |
| | CH64_873 | RIO1 family protein. (282 aa) |
| | phoQ | HAMP domain protein. (468 aa) |
| | nagK | Glucokinase family protein; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P. (304 aa) |
| | thiK | Thiamine kinase; Catalyzes the phosphorylation of thiamine to thiamine phosphate. (293 aa) |
| | ptsG | PTS system glucose-specific EIICB component. (477 aa) |
