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nanT nanT dctA_2 dctA_2 AKA38766.1 AKA38766.1 atpC atpC atpD atpD atpG atpG atpA atpA atpH atpH atpF atpF atpE atpE atpB atpB trkD trkD gltC_1 gltC_1 fieF fieF sth sth corA corA zntA zntA trkH trkH panF panF mgtA mgtA sstT sstT foxA foxA entS entS yggA yggA lplT lplT metN metN hcaT hcaT AKA37979.1 AKA37979.1 AKA37978.1 AKA37978.1 mgtE mgtE feoB feoB mntH mntH ccmA ccmA sdcS sdcS nuoB nuoB fruA fruA fliI fliI sfuC sfuC yebN yebN tppB-2 tppB-2 qacE qacE pntA pntA pntB pntB tonB tonB nhaB nhaB emrE2 emrE2 mdtJ mdtJ znuC znuC tppB tppB dtpA dtpA hoxN hoxN chaA chaA dtpT dtpT cvrA cvrA AKA39805.1 AKA39805.1 AKA39785.1 AKA39785.1 fieF_1 fieF_1 AKA39732.1 AKA39732.1 ybhF ybhF AKA39684.1 AKA39684.1 kdpA kdpA kdpB kdpB kdpC kdpC AKA39555.1 AKA39555.1 copA copA rosB rosB amtB_2 amtB_2 cyoA cyoA cyoB cyoB cyoC cyoC cyoD cyoD fhuA fhuA ysaN ysaN setA setA thiQ thiQ nhaA nhaA gltP_2 gltP_2 trkA trkA kefB kefB
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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nanTSialic acid transporter; Catalyzes the proton-dependent transport of sialic acid. Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family. (496 aa)
dctA_2C4-dicarboxylate transporter; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (430 aa)
AKA38766.1Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (552 aa)
atpCATP synthase F0F1 subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane. (140 aa)
atpDATP synthase F0F1 subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (460 aa)
atpGATP F0F1 synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (289 aa)
atpAATP F0F1 synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (513 aa)
atpHATP F0F1 synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (177 aa)
atpFATP F0F1 synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (156 aa)
atpEATP F0F1 synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (79 aa)
atpBATP synthase F0F1 subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (274 aa)
trkDPotassium transport protein Kup; Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system); Belongs to the HAK/KUP transporter (TC 2.A.72) family. (622 aa)
gltC_1Sodium:glutamate symporter; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family. (404 aa)
fieFFerrous iron transporter; Cation-efflux transporter that may have a role in detoxification. (300 aa)
sthPyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (466 aa)
corAMagnesium transporter CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family. (316 aa)
zntAZinc ABC transporter ATPase; P-type ATPase involved in the export of lead, cadmium, zinc and mercury; Derived by automated computational analysis using gene prediction method: Protein Homology. (742 aa)
trkHPotassium transporter; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family. (483 aa)
panFSodium/panthothenate symporter; Mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (484 aa)
mgtAMagnesium ABC transporter ATPase; P-type; involved in magnesium transport into the cytoplasm; Derived by automated computational analysis using gene prediction method: Protein Homology. (906 aa)
sstTSerine/threonine protein kinase; Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system). Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (415 aa)
foxAFerrichrysobactin receptor; Derived by automated computational analysis using gene prediction method: Protein Homology. (735 aa)
entSPOT family transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa)
yggAArginine exporter protein; Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine; Belongs to the LysE/ArgO transporter (TC 2.A.75) family. (202 aa)
lplTLysophospholipid transporter LplT; Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell; Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family. (403 aa)
metNDL-methionine transporter ATP-binding subunit; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (343 aa)
hcaT3-phenylpropionic acid transporter; Transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
AKA37979.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
AKA37978.1Nickel transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NiCoT transporter (TC 2.A.52) family. (339 aa)
mgtEDihydroorotate dehydrogenase; Acts as a magnesium transporter. (489 aa)
feoBFerrous iron transporter B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. (770 aa)
mntHManganese transport protein MntH; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family. (409 aa)
ccmACytochrome C biogenesis protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (208 aa)
sdcSCitrate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (610 aa)
nuoBNADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (225 aa)
fruAPTS system fructose-specific transporter subunits IIBC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. (558 aa)
fliIATP synthase; Involved in type III protein export during flagellum assembly; Derived by automated computational analysis using gene prediction method: Protein Homology. (454 aa)
sfuCAmino acid ABC transporter substrate-binding protein; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system. (349 aa)
yebNHypothetical protein; Probably functions as a manganese efflux pump. Belongs to the MntP (TC 9.B.29) family. (189 aa)
tppB-2Peptide ABC transporter permease; Proton-dependent permease that transports di- and tripeptides; Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily. (504 aa)
qacEMultidrug DMT transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (110 aa)
pntANAD(P) transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. (509 aa)
pntBPyridine nucleotide transhydrogenase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (462 aa)
tonBEnergy transducer TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. (244 aa)
nhaBSodium:proton antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family. (524 aa)
emrE2Multidrug transporter; Catalyzes the excretion of spermidine. (109 aa)
mdtJSpermidine export protein MdtJ; Catalyzes the excretion of spermidine. (144 aa)
znuCZinc ABC transporter ATPase; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. (252 aa)
tppBPeptide ABC transporter permease; Proton-dependent permease that transports di- and tripeptides; Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpB subfamily. (493 aa)
dtpAMFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (504 aa)
hoxNNickel transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NiCoT transporter (TC 2.A.52) family. (341 aa)
chaACalcium/sodium:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (369 aa)
dtpTAmino acid transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (507 aa)
cvrAPotassium/proton antiporter; K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily. (575 aa)
AKA39805.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
AKA39785.1Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (562 aa)
fieF_1Cation transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (463 aa)
AKA39732.1Magnesium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
ybhFMultidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (580 aa)
AKA39684.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (681 aa)
kdpAPotassium-transporting ATPase subunit A; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. (562 aa)
kdpBPotassium-transporting ATPase subunit B; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (688 aa)
kdpCPotassium-transporting ATPase subunit C; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (200 aa)
AKA39555.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa)
copACopper-transporting ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (911 aa)
rosBCation:proton antiport protein; YbaL; member of the CPA-2 family of antiporters; uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (563 aa)
amtB_2Ammonium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (429 aa)
cyoAUbiquinol oxidase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
cyoBCytochrome o ubiquinol oxidase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the heme-copper respiratory oxidase family. (663 aa)
cyoCCytochrome o ubiquinol oxidase subunit III; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
cyoDHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (110 aa)
fhuATonB-dependent receptor; Derived by automated computational analysis using gene prediction method: Protein Homology. (706 aa)
ysaNATP synthase; Invasion protein InvC; necessary for efficient entry of S.typhimurium into cultured epithelial cells; probable catalytic subunit of a protein translocase; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)
setASugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)
thiQThiamine ABC transporter ATP-binding protein; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family. (233 aa)
nhaApH-dependent sodium/proton antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. (394 aa)
gltP_2Glutamate:protein symporter; Catalyzes the proton-dependent transport of glutamate and aspartate; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily. (438 aa)
trkAInvolved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa)
kefBPotassium transporter KefB; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. (601 aa)
Your Current Organism:
Yersinia ruckeri
NCBI taxonomy Id: 29486
Other names: ATCC 29473, CCM 6093, CCUG 14190, CDC 2396-61, CIP 82.80, DSM 18506, JCM 15110, JCM 2429, NCIB 2194, NCIMB 2194, NCTC 12986, Y. ruckeri
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