(10 nodes) Mixed, incl. tRNA-dihydrouridine synthase, and His-Me finger superfamily network (Aeromonas salmonicida)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	dusC	Unannotated protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. (314 aa)
	GCA_000820065_00949	Unannotated protein. (243 aa)
	A4SK85_AERS4	Unannotated protein. (229 aa)
	sprT	Unannotated protein; Belongs to the SprT family. (177 aa)
	prmA	Unannotated protein; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. (292 aa)
	dusB	Unannotated protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. (321 aa)
	fis	Unannotated protein; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. (98 aa)
	A4STA5_AERS4	Unannotated protein. (420 aa)
	czcD-2	Unannotated protein; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (303 aa)
	trmL	Unannotated protein; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. (154 aa)

Your Current Organism:

Aeromonas salmonicida

NCBI taxonomy Id: 29491
Other names: A. salmonicida subsp. salmonicida, Aeromonas salmonicida salmonicida, Aeromonas salmonicida subsp. salmonicida

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A4SK85_AERS4	GCA_000820065_00949	GCA_000820065_00950	GCA_000820065_00949	Unannotated protein.	Unannotated protein.	0.835
A4SK85_AERS4	sprT	GCA_000820065_00950	GCA_000820065_00951	Unannotated protein.	Unannotated protein; Belongs to the SprT family.	0.689
A4STA5_AERS4	czcD-2	GCA_000820065_04454	GCA_000820065_04456	Unannotated protein.	Unannotated protein; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.	0.714
GCA_000820065_00949	A4SK85_AERS4	GCA_000820065_00949	GCA_000820065_00950	Unannotated protein.	Unannotated protein.	0.835
GCA_000820065_00949	prmA	GCA_000820065_00949	GCA_000820065_01227	Unannotated protein.	Unannotated protein; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.	0.926
GCA_000820065_00949	sprT	GCA_000820065_00949	GCA_000820065_00951	Unannotated protein.	Unannotated protein; Belongs to the SprT family.	0.567
GCA_000820065_00949	trmL	GCA_000820065_00949	GCA_000820065_04459	Unannotated protein.	Unannotated protein; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.	0.421
czcD-2	A4STA5_AERS4	GCA_000820065_04456	GCA_000820065_04454	Unannotated protein; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.	Unannotated protein.	0.714
czcD-2	trmL	GCA_000820065_04456	GCA_000820065_04459	Unannotated protein; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.	Unannotated protein; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.	0.473
dusB	dusC	GCA_000820065_03846	GCA_000820065_00700	Unannotated protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.	Unannotated protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.	0.413
dusB	fis	GCA_000820065_03846	GCA_000820065_03847	Unannotated protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.	Unannotated protein; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.	0.997
dusB	prmA	GCA_000820065_03846	GCA_000820065_01227	Unannotated protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.	Unannotated protein; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.	0.762
dusC	dusB	GCA_000820065_00700	GCA_000820065_03846	Unannotated protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.	Unannotated protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.	0.413
dusC	fis	GCA_000820065_00700	GCA_000820065_03847	Unannotated protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.	Unannotated protein; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.	0.858
fis	dusB	GCA_000820065_03847	GCA_000820065_03846	Unannotated protein; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.	Unannotated protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.	0.997
fis	dusC	GCA_000820065_03847	GCA_000820065_00700	Unannotated protein; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.	Unannotated protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.	0.858
fis	prmA	GCA_000820065_03847	GCA_000820065_01227	Unannotated protein; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.	Unannotated protein; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.	0.827
prmA	GCA_000820065_00949	GCA_000820065_01227	GCA_000820065_00949	Unannotated protein; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.	Unannotated protein.	0.926
prmA	dusB	GCA_000820065_01227	GCA_000820065_03846	Unannotated protein; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.	Unannotated protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.	0.762
prmA	fis	GCA_000820065_01227	GCA_000820065_03847	Unannotated protein; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.	Unannotated protein; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.	0.827