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| | lpxC | Unannotated protein; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (282 aa) |
| | A4SQW3_AERS4 | Unannotated protein. (327 aa) |
| | fabH-2 | Unannotated protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (362 aa) |
| | cdsA | Unannotated protein; Belongs to the CDS family. (285 aa) |
| | dxr | Unannotated protein; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (397 aa) |
| | lpxD | Unannotated protein; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (339 aa) |
| | fabZ | Unannotated protein; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (153 aa) |
| | lpxA | Unannotated protein; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (263 aa) |
| | lpxB | Unannotated protein; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (379 aa) |
| | accA | Unannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (316 aa) |
| | gpsA | Unannotated protein; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (334 aa) |
| | pss | Unannotated protein. (449 aa) |
| | A4SI33_AERS4 | Unannotated protein. (778 aa) |
| | A4SHX3_AERS4 | Unannotated protein; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. (184 aa) |
| | lpxH | Unannotated protein; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (254 aa) |
| | lapA | Unannotated protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. (94 aa) |
| | lapB | Unannotated protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family. (388 aa) |
| | htrB | Unannotated protein; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). (316 aa) |
| | kdsA | Unannotated protein; Belongs to the KdsA family. (284 aa) |
| | A4SKY1_AERS4 | Unannotated protein. (353 aa) |
| | A4SKY2_AERS4 | Unannotated protein. (306 aa) |
| | rfbD | Unannotated protein; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (295 aa) |
| | fadB | Unannotated protein; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (715 aa) |
| | fadA | Unannotated protein; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (387 aa) |
| | mccB | Unannotated protein. (539 aa) |
| | mccA | Unannotated protein. (661 aa) |
| | A4STC8_AERS4 | Unannotated protein. (347 aa) |
| | rfaQ | Unannotated protein. (281 aa) |
| | rfaF | Unannotated protein. (371 aa) |
| | kdtA-2 | Unannotated protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (421 aa) |
| | plsB | Unannotated protein; Belongs to the GPAT/DAPAT family. (807 aa) |
| | elbB | Unannotated protein; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate; Belongs to the peptidase C56 family. (216 aa) |
| | plsY | Unannotated protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (236 aa) |
| | A4SI89_AERS4 | Unannotated protein. (464 aa) |
| | murG | Unannotated protein; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (361 aa) |
| | A4SRZ5_AERS4 | Unannotated protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (268 aa) |
| | A4SS05_AERS4 | Unannotated protein. (131 aa) |
| | cysQ-2 | Unannotated protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (270 aa) |
| | A4SHC1_AERS4 | Unannotated protein. (373 aa) |
| | waaL | Unannotated protein. (403 aa) |
| | lbgA | Unannotated protein. (227 aa) |
| | lbgB | Unannotated protein. (350 aa) |
| | A4SHC6_AERS4 | Unannotated protein. (354 aa) |
| | A4SHG6_AERS4 | Unannotated protein. (70 aa) |
| | A4SHH3_AERS4 | Unannotated protein. (404 aa) |
| | A4SPI9_AERS4 | Unannotated protein. (132 aa) |
| | A4SPC1_AERS4 | Unannotated protein. (156 aa) |
| | A4SP76_AERS4 | Unannotated protein. (206 aa) |
| | GCA_000820065_00223 | Unannotated protein. (550 aa) |
| | ispG | Unannotated protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (355 aa) |
| | A4SNY4_AERS4 | Unannotated protein. (757 aa) |
| | A4SNY3_AERS4 | Unannotated protein. (362 aa) |
| | A4SNW8_AERS4 | Unannotated protein. (355 aa) |
| | A4SNW4_AERS4 | Unannotated protein. (548 aa) |
| | dgkA | Unannotated protein; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (126 aa) |
| | fadJ | Unannotated protein; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (717 aa) |
| | fadI | Unannotated protein; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (436 aa) |
| | atoB | Unannotated protein; Belongs to the thiolase-like superfamily. Thiolase family. (334 aa) |
| | msbB2 | Unannotated protein; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A. (328 aa) |
| | msbB1 | Unannotated protein; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A. (340 aa) |
| | fabV | Unannotated protein; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (395 aa) |
| | kdtA | Unannotated protein; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family. (237 aa) |
| | A4SH75_AERS4 | Unannotated protein. (351 aa) |
| | glmU | Unannotated protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (453 aa) |
| | prpD | Unannotated protein. (860 aa) |
| | fabF | Unannotated protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (413 aa) |
| | acpP | Unannotated protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (78 aa) |
| | fabD | Unannotated protein. (308 aa) |
| | fabH | Unannotated protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (319 aa) |
| | plsX | Unannotated protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (339 aa) |
| | A4SML9_AERS4 | Unannotated protein. (395 aa) |
| | pgpB | Unannotated protein. (240 aa) |
| | accD | Unannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (287 aa) |
| | A4SNS8_AERS4 | Unannotated protein. (210 aa) |
| | A4SQ83_AERS4 | Unannotated protein. (373 aa) |
| | A4SK94_AERS4 | Unannotated protein. (391 aa) |
| | A4SK96_AERS4 | Unannotated protein. (344 aa) |
| | A4SKD7_AERS4 | Unannotated protein. (160 aa) |
| | ispD | Unannotated protein; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (229 aa) |
| | ispF | Unannotated protein; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (158 aa) |
| | A4SUQ3_AERS4 | Unannotated protein. (540 aa) |
| | A4SUQ2_AERS4 | Unannotated protein. (541 aa) |
| | A4SJL0_AERS4 | Unannotated protein. (295 aa) |
| | pgsA | Unannotated protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (201 aa) |
| | A4SKI3_AERS4 | Unannotated protein. (235 aa) |
| | A4SKH8_AERS4 | Unannotated protein. (80 aa) |
| | cls | Unannotated protein; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (493 aa) |
| | ispA | Unannotated protein; Belongs to the FPP/GGPP synthase family. (296 aa) |
| | dxs | Unannotated protein; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (621 aa) |
| | pgpA | Unannotated protein; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). (164 aa) |
| | accB | Unannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (144 aa) |
| | accC | Unannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (446 aa) |
| | GCA_000820065_01234 | Unannotated protein. (180 aa) |
| | GCA_000820065_01235 | Unannotated protein. (203 aa) |
| | A4SHI7_AERS4 | Unannotated protein. (334 aa) |
| | A4SHQ0_AERS4 | Unannotated protein; Belongs to the phosphatidylserine decarboxylase family. (456 aa) |
| | ackA | Unannotated protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (399 aa) |
| | A4SNI3_AERS4 | Unannotated protein. (554 aa) |
| | A4SNE7_AERS4 | Unannotated protein. (547 aa) |
| | fabB | Unannotated protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (403 aa) |
| | A4SNB3_AERS4 | Unannotated protein. (388 aa) |
| | phaJ | Unannotated protein. (136 aa) |
| | A4SJ76_AERS4 | Unannotated protein. (236 aa) |
| | A4SJ18_AERS4 | Unannotated protein. (630 aa) |
| | faa1 | Unannotated protein. (596 aa) |
| | A4SJ04_AERS4 | Unannotated protein. (328 aa) |
| | ispH | Unannotated protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (311 aa) |
| | A4SIT4_AERS4 | Unannotated protein. (187 aa) |
| | plsC | Unannotated protein; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (242 aa) |
| | wbgZ | Unannotated protein. (661 aa) |
| | A4SSV9_AERS4 | Unannotated protein. (219 aa) |
| | FABV_AERS4 | Unannotated protein; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the NADH-dependent reduction of the carbon-carbon double bond in the enoyl moiety that is covalently linked to an acyl carrier protein (ACP). (397 aa) |
| | A4SPN3_AERS4 | Unannotated protein. (541 aa) |
| | psd | Unannotated protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (290 aa) |
| | A4SJH0_AERS4 | Unannotated protein. (239 aa) |
| | plsC-2 | Unannotated protein. (252 aa) |
| | acpP2 | Unannotated protein. (88 aa) |
| | acpP-2 | Unannotated protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (82 aa) |
| | A4SJH6_AERS4 | Unannotated protein. (123 aa) |
| | A4SJH7_AERS4 | Unannotated protein. (567 aa) |
| | fabF-2 | Unannotated protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (393 aa) |
| | A4SJI7_AERS4 | Unannotated protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (408 aa) |
| | A4SJZ5_AERS4 | Unannotated protein. (498 aa) |
| | lipA | Unannotated protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (326 aa) |
| | pld | Unannotated protein. (417 aa) |
| | A4SSP5_AERS4 | Unannotated protein. (206 aa) |
| | neuA | Unannotated protein. (231 aa) |
| | A4SHH8_AERS4 | Unannotated protein. (77 aa) |
| | A4SHI4_AERS4 | Unannotated protein. (321 aa) |
| | lpxK | Unannotated protein; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (331 aa) |
| | kdsB | Unannotated protein; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (259 aa) |
| | pgsA-2 | Unannotated protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (184 aa) |
| | fabA | Unannotated protein; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (186 aa) |
| | GCA_000820065_03857 | Unannotated protein. (604 aa) |
| | A4SPM9_AERS4 | Unannotated protein. (378 aa) |
| | cysQ | Unannotated protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (256 aa) |
| | ackA-2 | Unannotated protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa) |
| | ispB | Unannotated protein; Belongs to the FPP/GGPP synthase family. (323 aa) |
| | arnF | Unannotated protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnF family. (148 aa) |
| | arnE | Unannotated protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnE family. (114 aa) |
| | arnT | Unannotated protein; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family. (547 aa) |
| | arnD | Unannotated protein; Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily. (299 aa) |
| | arnA | Unannotated protein; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. (499 aa) |
| | arnC | Unannotated protein; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. (325 aa) |
| | arnB | Unannotated protein; Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily. (378 aa) |
